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Thenalidine

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Thenalidine
Clinical data
ATC code
Identifiers
  • 1-Methyl-N-phenyl-N-(2-thienylmethyl)piperidin-4-amine
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard 100.001.501 Edit this at Wikidata
Chemical and physical data
Formula C17H22N2S
Molar mass 286.44g·mol−1
3D model (JSmol)
  • s1c(ccc1)CN(c2ccccc2)C3CCN(C)CC3
  • InChI=1S/C17H22N2S/c1-18-11-9-16(10-12-18)19(14-17-8-5-13-20-17)15-6-3-2-4-7-15/h2-8,13,16H,9-12,14H2,1H3[画像:X mark]N
  • Key:KLOHYVOVXOUKQI-UHFFFAOYSA-N[画像:X mark]N
[画像:X mark]N[画像:check]Y(what is this?) (verify)

Thenalidine is an antihistamine with anticholinergic properties used as an antipruritic drug.[1] It was withdrawn from the US, Canadian, and UK markets in 1963 due to a risk of neutropenia.[2]

References

[edit ]
  1. ↑ Getzler NA, Ereaux LP (March 1959). "Evaluation of thenalidine tratrate (sandostene) in dermatological disorders". Canadian Medical Association Journal. 80 (6): 445–8. PMC 1830689 . PMID 13629433.
  2. ↑ "Thenalidine". DrugBank.
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