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Tectonin beta-propeller repeat containing 1

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
TECPR1
Available structures
PDB Ortholog search: PDBe RCSB
List of PDB id codes

4TQ1

Identifiers
Aliases TECPR1 , tectonin beta-propeller repeat containing 1
External IDsOMIM: 614781; MGI: 1917631; HomoloGene: 9120; GeneCards: TECPR1; OMA:TECPR1 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr. Chromosome 7 (human) [1]
Band 7q21.3Start98,214,624 bp [1]
End98,252,232 bp [1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr. Chromosome 5 (mouse)[2]
Band 5|5 G2Start144,131,260 bp [2]
End144,160,433 bp [2]
RNA expression pattern
Bgee
Human Mouse (ortholog)
  • parotid gland

  • pancreatic ductal cell

  • mucosa of ileum

  • endothelial cell

  • sural nerve

  • trachea

  • granulocyte

  • middle temporal gyrus

  • prefrontal cortex

  • tibialis anterior muscle
  • lacrimal gland

  • Rostral migratory stream

  • cerebellar cortex

  • internal carotid artery

  • iris

  • motor neuron

  • thymus

  • substantia nigra

  • neural layer of retina

  • external carotid artery
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

25851

70381

Ensembl

ENSG00000205356

ENSMUSG00000066621

UniProt

Q7Z6L1

Q80VP0

RefSeq (mRNA)

NM_015395

NM_027410
NM_001356992
NM_001356993

RefSeq (protein)

NP_056210

NP_081686
NP_001343921
NP_001343922

Location (UCSC)Chr 7: 98.21 – 98.25 Mb Chr 5: 144.13 – 144.16 Mb
PubMed search[3] [4]
Wikidata

Tectonin beta-propeller repeat containing 1 is a protein that in humans is encoded by the TECPR1 gene. [5]

Function

[edit ]

This gene encodes a tethering factor involved in autophagy. The encoded protein is found at autolysosomes, and is involved in targeting protein aggregates, damaged mitochondria, and bacterial pathogens for autophagy

References

[edit ]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000205356Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000066621Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Tectonin beta-propeller repeat containing 1" . Retrieved 2017年01月03日.

Further reading

[edit ]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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