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Talk:Thyroid hormone receptor

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Latest comment: 2 months ago by Pabnau in topic Nongenomic effects
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Wiki Education Foundation-supported course assignment

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Latest comment: 4 years ago 1 comment1 person in discussion

This article was the subject of a Wiki Education Foundation-supported course assignment, between 15 January 2019 and 29 April 2019. Further details are available on the course page. Student editor(s): Arizzo0226.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 11:21, 17 January 2022 (UTC) Reply

Assessment comment

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Latest comment: 5 years ago 3 comments3 people in discussion

The comment(s) below were originally left at Talk:Thyroid hormone receptor/Comments Talk:Thyroid hormone receptor/Comments , and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

A reference to the fact that thyroid hormone receptors are always located in the nucleus vs. all other steroid type hormone receptors which are located both in nucleus and cytoplasm ought to be included as this is a fundamental difference in these receptors. Also that thyroid hormone receptors are constitutively bound to DNA without being bound to ligands (thyroid hormone). Nairwin (talk) 16:20, 12 June 2009 (UTC) Reply

Last edited at 16:20, 12 June 2009 (UTC). Substituted at 08:43, 30 April 2016 (UTC)

What is the article's overall status? It seems like it's complete and understandable.

What are the article's strengths? It addresses information about what the hormone is, how it functions and how it impacts people when it's mutated or not functioning which provides a general audience with a full spectrum of information all in one place. How can the article be improved? I think updating the sources would be a start. How would you assess the article's completeness - i.e. Is the article well-developed? Is it underdeveloped or poorly developed? Well- developed. KNavarra (talk) 19:13, 30 January 2020 (UTC)knavarraReply

How can the article be improved? More recent sources could be added, as well as a structural diagram (perhaps for alpha and beta types) and more information on disease treatment. Pdietry (talk) 03:59, 5 October 2020 (UTC) Reply

Nongenomic effects

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Latest comment: 2 months ago 1 comment1 person in discussion

I think the information about nongenomic effects needs some cleaning and updating. There seems to be a lot of speculative claims based on early research. This article doesn’t seem to be clearly distinguishing between what we know, and various speculative explanations researchers were proposing to try to explain it, which are often described in the literature as "potential" or "purported."

So many of the core sources are also behind paywalls, which makes verification hard, but I suspect some of these citations may be erroneous. For example, as far as I was able to find Pediatric Endocrinology (2014) doesn’t say anything about nongenomic effects of thyroid hormones, though it talks a bit about possible transmembrane receptors for other nuclear receptors.

If I find some time, I’ll try to find some more recent and easily available review articles, but I thought I’d leave a comment here about some of the red flags I’ve run into Pabnau (talk) 21:27, 4 June 2026 (UTC) Reply

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