Jump to content

Wikipedia The Free Encyclopedia

TRAPPC8

From Wikipedia, the free encyclopedia

Protein-coding gene in the species Homo sapiens

TRAPPC8

Identifiers

TRAPPC8 , GSG1, HsT2706, KIAA1012, TRS85, trafficking protein particle complex 8, trafficking protein particle complex subunit 8

External IDs

OMIM: 614136; MGI: 2443008; GeneCards: TRAPPC8

Gene location (Human)
Chromosome 18 (human)
Chr.	Chromosome 18 (human) ^[1]
Chromosome 18 (human) Genomic location for TRAPPC8 Genomic location for TRAPPC8
Band	18q12.1	Start	31,829,197 bp ^[1]
Band	18q12.1	End	31,953,136 bp ^[1]

Gene location (Mouse)
Chromosome 18 (mouse)
Chr.	Chromosome 18 (mouse)^[2]
Chromosome 18 (mouse) Genomic location for TRAPPC8 Genomic location for TRAPPC8
Band	18\|18 A2	Start	20,950,280 bp ^[2]
Band	18\|18 A2	End	21,029,150 bp ^[2]

RNA expression pattern

Human	Mouse (ortholog)
Top expressed in hair follicle gonad jejunal mucosa caput epididymis sperm superior surface of tongue renal medulla cardia bronchial epithelial cell corpus epididymis	Top expressed in superior cervical ganglion otolith organ utricle hand retinal pigment epithelium skin of abdomen primary oocyte ciliary body cumulus cell transitional epithelium of urinary bladder
More reference expression data

More reference expression data

Gene ontology
Molecular function	protein binding
Cellular component	phagophore assembly site cytoplasmic vesicle TRAPPIII protein complex Golgi apparatus cytosol TRAPP complex
Biological process	protein localization to phagophore assembly site autophagy of peroxisome cytoplasm to vacuole transport by the Cvt pathway autophagy of nucleus endoplasmic reticulum to Golgi vesicle-mediated transport vesicle-mediated transport Golgi organization autophagosome assembly
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


22878


75964


ENSG00000153339


ENSMUSG00000033382


Q9Y2L5


n/a

RefSeq (mRNA)

NM_029491
NM_177038
NM_001361188
NM_001379370

RefSeq (protein)

n/a

Location (UCSC)

Chr 18: 31.83 – 31.95 Mb

Chr 18: 20.95 – 21.03 Mb

PubMed search

^[3]

^[4]

View/Edit Human View/Edit Mouse

Trafficking protein particle complex subunit 8 is a protein that in humans is encoded by the TRAPPC8 gene (previously KIAA1012).^[5]^[6]^[7] The TRAPPC8 protein is part of the TRAPP complex.^[7] It is involved in the organization of the golgi apparatus and in the production of collagen.^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000153339 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033382 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jul 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63 . PMID 10231032.
↑ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
1 2 3 "Entrez Gene: KIAA1012 KIAA1012".

Further reading

Kimura K, Wakamatsu A, Suzuki Y, etal. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.
Ballif BA, Villén J, Beausoleil SA, etal. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200 . PMID 15345747.
Ota T, Suzuki Y, Nishikawa T, etal. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285 . PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, etal. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Gavin AC, Bösche M, Krause R, etal. (2002). "Functional organization of the yeast proteome by systematic analysis of protein complexes". Nature. 415 (6868): 141–7. Bibcode:2002Natur.415..141G. doi:10.1038/415141a. PMID 11805826. S2CID 4425555.
Sacher M, Barrowman J, Schieltz D, etal. (2000). "Identification and characterization of five new subunits of TRAPP". Eur. J. Cell Biol. 79 (2): 71–80. doi:10.1078/S0171-9335(04)70009-6 . PMID 10727015.

This article on a gene on human chromosome 18 is a stub. You can help Wikipedia by adding missing information.

v
t
e

Retrieved from "https://en.wikipedia.org/w/index.php?title=TRAPPC8&oldid=1368691334"

Hidden categories: