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Soterenol

From Wikipedia, the free encyclopedia
Adrenergic bronchodilator
Pharmaceutical compound
Soterenol
Clinical data
Other namesMJ-1992
Drug class Adrenergic; Bronchodilator; Antiasthmatic; β-Adrenergic receptor agonist
Identifiers
  • N-[2-hydroxy-5-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl]methanesulfonamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
Formula C12H20N2O4S
Molar mass 288.36 g·mol−1
3D model (JSmol)
  • CC(C)NCC(C1=CC(=C(C=C1)O)NS(=O)(=O)C)O
  • InChI=1S/C12H20N2O4S/c1-8(2)13-7-12(16)9-4-5-11(15)10(6-9)14-19(3,17)18/h4-6,8,12-16H,7H2,1-3H3
  • Key:HHRNQOGXBRYCHF-UHFFFAOYSA-N

Soterenol (INN Tooltip International Nonproprietary Name), also known as soterenol hydrochloride (USAN Tooltip United States Adopted Name; developmental code name MJ-1992) in the case of the hydrochloride salt, is a drug of the phenethylamine family described as an adrenergic, bronchodilator, and antiasthmatic which was never marketed.[1] [2] [3] It is an analogue of salbutamol and acts as a β-adrenergic receptor agonist.[3] [2] The drug was first developed in 1964[3] and was first described in the literature by 1967.[1]

References

[edit ]
  1. ^ a b Elks J (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 1107. ISBN 978-1-4757-2085-3 . Retrieved 17 October 2024.
  2. ^ a b Morton I, Morton I, Hall J (1999). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Netherlands. p. 260. ISBN 978-0-7514-0499-9 . Retrieved 17 October 2024.
  3. ^ a b c Sneader W (2005). Drug Discovery: A History. Wiley. p. 191. ISBN 978-0-471-89979-2 . Retrieved 17 October 2024.
α1
Agonists
Antagonists
α2
Agonists
Antagonists
β
Agonists
Antagonists

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