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SCH-79687

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SCH-79687
Names
Preferred IUPAC name
N-(3,5-Dichlorophenyl)-N′-({4-[(1H-imidazol-4-yl)methyl]phenyl}methyl)urea
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25)[画像:check]Y
    Key:CXNCQFJNXQAFND-UHFFFAOYSA-N[画像:check]Y
  • InChI=1/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25)
    Key:CXNCQFJNXQAFND-UHFFFAOYAC
  • Clc1cc(cc(Cl)c1)NC(=O)NCc2ccc(cc2)Cc3c[nH]cn3
Properties
C18H16Cl2N4O
Molar mass 375.251 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25°C [77°F], 100kPa).
Chemical compound

SCH-79687 is a histamine antagonist selective for the H3 subtype.[1]

References

[edit ]
  1. ↑ McLeod, RL; Rizzo, CA; West, RE Jr; Aslanian, R; McCormick, K; Bryant, M; Hsieh, Y; Korfmacher, W; Mingo, GG; Varty, L; Williams, SM; Shih, NY; Egan, RW; Hey, JA (Jun 2003). "Pharmacological characterization of the novel histamine H3-receptor antagonist N-(3,5-dichlorophenyl)-N'-[[4-(1H-imidazol-4-ylmethyl)phenyl]-methyl]-urea (SCH 79687)". Journal of Pharmacology and Experimental Therapeutics. 305 (3): 1037–44. doi:10.1124/jpet.103.049254. PMID 12649305.
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