Rubidium-82 chloride

Rubidium-82 chloride
Names
IUPAC name Rubidium-82 chloride
Systematic IUPAC name (⁸²Rb)Rubidium chloride
Identifiers
CAS Number	132486-03-4 ^checkY
3D model (JSmol)	Interactive image
ChemSpider	64457 ^checkY
KEGG	D05773 ^checkY
PubChem CID	71357
UNII	F0Z746KRKQ ^checkY
CompTox Dashboard (EPA)	DTXSID60894902 Edit this at Wikidata
InChI InChI=1S/ClH.Rb/h1H;/q;+1/p-1/i;1-3^checkY Key: FGDZQCVHDSGLHJ-RYDPDVNUSA-M^checkY
SMILES [Cl-].[82Rb+]
Properties
Chemical formula	ClRb
Molar mass	117.371 g mol⁻¹
Pharmacology
ATC code	V09GX04 (WHO )
Related compounds
Other cations	Caesium chloride Lithium chloride Potassium chloride Rubidium chloride Sodium chloride
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Chemical compound

Rubidium-82 chloride is a form of rubidium chloride containing a radioactive isotope of rubidium. It is marketed under the brand name Cardiogen-82 by Bracco Diagnostics for use in Myocardial perfusion imaging.^[1] It is rapidly taken up by heart muscle cells, and therefore can be used to identify regions of heart muscle that are receiving poor blood flow in a technique called PET perfusion imaging.^[2] The half-life of rubidium-82 is only 1.27 minutes; it is normally produced at the place of use by rubidium generators.^[3]

References

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^ Wackers, Frans J. Th.; Bruni, Wendy; Zaret, Barry L. (2007年11月19日). "Rubidium-82 Generator". Nuclear cardiology: the basics: how to set up and maintain a laboratory. Springer. ISBN 978-1-58829-924-6.
^ Ballinger, James R. (2009). "PET Radiopharmaceuticals in Nuclear Cardiology: Current Status and Limitations". Integrating Cardiology for Nuclear Medicine Physicians. pp. 379–385. doi:10.1007/978-3-540-78674-0_32. ISBN 978-3-540-78673-3.
^ Gould, K. Lance; Goldstein, Richard A.; Mullani, Nizar A.; Kirkeeide, Richard L.; Wong, Wai-Hoi; Tewson, Timothy J.; Berridge, Marc S.; Bolomey, Leonard A.; Hartz, Ross K.; Smalling, Richard W.; Fuentes, Francisco; Nishikawa, Akira (1986). "Noninvasive assessment of coronary stenoses by myocardial perfusion imaging during pharmacologic coronary vasodilation. VIII. Clinical feasibility of positron cardiac imaging without a cyclotron using generator-produced Rubidium-82". Journal of the American College of Cardiology. 7 (4): 775–789. doi:10.1016/S0735-1097(86)80336-9 . PMID 3485669.

Clarke, Michael J; Sadler, P. J (1999年06月15日). Metallopharmaceuticals: Diagnosis and therapy. Springer. ISBN 978-3-540-65308-0. (Note: only about 1/2 page on Rb-generator)
Alvarez-Diez, T; Dekemp, R; Beanlands, R; Vincent, J (1999). "Manufacture of strontium-82/rubidium-82 generators and quality control of rubidium-82 chloride for myocardial perfusion imaging in patients using positron emission tomography". Applied Radiation and Isotopes. 50 (6): 1015–23. doi:10.1016/S0969-8043(98)00170-5. PMID 10355104.
Waters, S. L.; Coursey, B. M., eds. (1987). "The Strontium-82/rubidium-82 generator". International Journal of Radiation Applications and Instrumentation A. 38 (3): 171–239.