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RALGAPB

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
RALGAPB
Identifiers
Aliases RALGAPB , KIAA1219, RalGAPbeta, Ral GTPase activating protein non-catalytic beta subunit, Ral GTPase activating protein non-catalytic subunit beta
External IDsMGI: 2444531; GeneCards: RALGAPB
Gene location (Human)
Chromosome 20 (human)
Chr. Chromosome 20 (human) [1]
Band 20q11.23Start38,472,816 bp [1]
End38,578,859 bp [1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr. Chromosome 2 (mouse)[2]
Band 2|2 H1Start158,251,768 bp [2]
End158,341,173 bp [2]
RNA expression pattern
Bgee
Human Mouse (ortholog)
  • buccal mucosa cell

  • sperm

  • endothelial cell

  • secondary oocyte

  • middle temporal gyrus

  • seminal vesicula

  • skin of thigh

  • Brodmann area 23

  • visceral pleura

  • corpus epididymis
  • substantia nigra

  • otolith organ

  • secondary oocyte

  • utricle

  • fossa

  • condyle

  • hand

  • epithelium of lens

  • facial motor nucleus

  • primary oocyte
More reference expression data
BioGPS


Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

57148

228850

Ensembl

ENSG00000170471

ENSMUSG00000027652

UniProt

Q86X10

Q8BQZ4

RefSeq (mRNA)

NM_001282917
NM_001282918
NM_020336

NM_001291137
NM_001291138
NM_177227
NM_177658
NM_001363006

NM_001369183

RefSeq (protein)

NP_001269846
NP_001269847
NP_065069

n/a

Location (UCSC)Chr 20: 38.47 – 38.58 Mb Chr 2: 158.25 – 158.34 Mb
PubMed search[3] [4]
Wikidata

Ral GTPase-activating protein subunit beta is a protein that in humans is encoded by the RALGAPB gene (previously KIAA1219).[5] [6] It is predicted to be a (non-enzymatic) subunit of the RalGAP1 and RalGAP2 protein complexes which are involved in activating the small GTPases RALA and RALB.[7]

References

[edit ]
  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000170471 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027652 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Shirakawa R, Fukai S, Kawato M, Higashi T, Kondo H, Ikeda T, Nakayama E, Okawa K, Nureki O, Kimura T, Kita T, Horiuchi H (Aug 2009). "Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases". J Biol Chem. 284 (32): 21580–8. doi:10.1074/jbc.M109.012112 . PMC 2755882 . PMID 19520869.
  6. "Entrez Gene: KIAA1219 KIAA1219".
  7. "Ral GTPase-activating protein subunit beta". uniprot.org. UniProt consortium. Retrieved 2026年08月03日.

Further reading

[edit ]
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