RAI1

Mammalian protein found in Homo sapiens

This article is about the protein. For the Italian television channel, see Rai 1.

RAI1

Identifiers

RAI1 , SMCR, SMS, retinoic acid induced 1

External IDs

Gene location (Human)
Chromosome 17 (human)
Chr.	Chromosome 17 (human) ^[1]
Chromosome 17 (human) Genomic location for RAI1 Genomic location for RAI1
Band	17p11.2	Start	17,681,458 bp ^[1]
Band	17p11.2	End	17,811,453 bp ^[1]

Gene location (Mouse)
Chromosome 11 (mouse)
Chr.	Chromosome 11 (mouse)^[2]
Chromosome 11 (mouse) Genomic location for RAI1 Genomic location for RAI1
Band	11\|11 B1.3-B2	Start	60,105,013 bp ^[2]
Band	11\|11 B1.3-B2	End	60,199,197 bp ^[2]

Human	Mouse (ortholog)
Top expressed in retinal pigment epithelium nipple palpebral conjunctiva urethra pylorus tibia Brodmann area 23 cardia human penis Parietal Lobe	Top expressed in lateral septal nucleus habenula anterior amygdaloid area olfactory tubercle ventromedial nucleus subiculum dorsomedial hypothalamic nucleus Rostral migratory stream lateral hypothalamus mammillary body
More reference expression data

n/a

Gene ontology
Molecular function	protein binding metal ion binding DNA-binding transcription factor activity
Cellular component	cytoplasm mitochondrion nucleoplasm nucleus
Biological process	positive regulation of transcription, DNA-templated skeletal system development negative regulation of multicellular organism growth regulation of transcription by RNA polymerase II circadian regulation of gene expression rhythmic process positive regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO

Species

Human

Mouse

Entrez


10743


19377


ENSG00000108557


ENSMUSG00000062115


Q7Z5J4


Q61818

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

^[3]

^[4]

RAI1 is a transcription factor associated with Smith–Magenis syndrome when individuals have deletions of the gene and Potocki–Lupski syndrome when individuals have a duplication. It is known as retinoic acid induced 1.