Jump to content
Wikipedia The Free Encyclopedia

Nucleoporin 188

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
NUP188
Available structures
PDB Ortholog search: PDBe RCSB
List of PDB id codes

5IJO

Identifiers
Aliases NUP188 , KIAA0169, hNup188, nucleoporin 188kDa, nucleoporin 188, SANDSTEF
External IDsOMIM: 615587; MGI: 2446190; HomoloGene: 45683; GeneCards: NUP188; OMA:NUP188 - orthologs
Gene location (Human)
Chromosome 9 (human)
Chr. Chromosome 9 (human) [1]
Band 9q34.11Start128,947,699 bp [1]
End129,007,096 bp [1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr. Chromosome 2 (mouse)[2]
Band 2|2 BStart30,176,409 bp [2]
End30,234,278 bp [2]
RNA expression pattern
Bgee
Human Mouse (ortholog)
  • right testis

  • left testis

  • cerebellar hemisphere

  • right hemisphere of cerebellum

  • anterior pituitary

  • testicle

  • stromal cell of endometrium

  • skin of leg

  • gastric mucosa

  • ectocervix
  • spermatocyte

  • spermatid

  • seminiferous tubule

  • epiblast

  • tail of embryo

  • ventricular zone

  • Gonadal ridge

  • zygote

  • maxillary prominence

  • mandibular prominence
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

23511

227699

Ensembl

ENSG00000095319

ENSMUSG00000052533

UniProt

Q5SRE5

Q6ZQH8

RefSeq (mRNA)

NM_015354

NM_198304

RefSeq (protein)

NP_056169

NP_938046

Location (UCSC)Chr 9: 128.95 – 129.01 Mb Chr 2: 30.18 – 30.23 Mb
PubMed search[3] [4]
Wikidata

Nucleoporin 188 (Nup188) is a protein that in humans is encoded by the NUP188 gene.[5] [6]

Function

[edit ]

Transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP188 is part of one such subcomplex.[5]

References

[edit ]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000095319Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000052533Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: NUP188 nucleoporin 188kDa".
  6. ^ Miller BR, Powers M, Park M, Fischer W, Forbes DJ (October 2000). "Identification of a New Vertebrate Nucleoporin, Nup188, with the Use of a Novel Organelle Trap Assay". Mol. Biol. Cell. 11 (10): 3381–96. doi:10.1091/mbc.11.10.3381. PMC 15000 . PMID 11029043.
[edit ]
  • Overview of all the structural information available in the PDB for UniProt: Q5SRE5 (Human Nucleoporin NUP188 homolog (NUP188)) at the PDBe-KB.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


Stub icon

This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by expanding it.

AltStyle によって変換されたページ (->オリジナル) /