Lagochilin
From Wikipedia, the free encyclopedia
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| IUPAC name
(13S)-9α,13-Epoxy-8α-labdane-3β,15,16,18-tetrol
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| Systematic IUPAC name
(1R,2R,4aS,5R,5′S,6S)-5′-(2-Hydroxyethyl)-5,5′-bis(hydroxymethyl)-2,5,8a-trimethyloctahydro-2H-spiro[naphthalene-1,2′-oxolan]-6-ol | |
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3D model (JSmol)
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PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C20H36O5 | |
| Molar mass | 356.495 g/mol |
| Appearance | Light grey crystalline solid |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Lagochilin is a bitter diterpene that forms a grey crystalline solid. It is found in various plants from the genus Lagochilus , most notably Lagochilus inebrians , and is thought to be responsible for the sedative, hypotensive and hemostatic effects of these plant species.[1] [2] [3] [4]
References
[edit ]- ^ Pulatova TP, Khazanovich RL (1962). "[On the alkaloid content of some Lagochilus species and on the nature of lagochiline]". Aptechnoe Delo. 6: 29–32. PMID 13972488.
- ^ Mavlyankulova ZI, Zainutdinov UN, Mukhamedkhanov SI, Leont'ev VD, Aslanov KA (1980). "Investigation of the Lagochiline Acetylation Reaction". Khimiya Prirodnykh Soedinenii. 1: 46–9.
- ^ Chizhov OS, Kessenikh AV, Yakovlev IP, Zolotarev BM, Petukhov VA, Zelinsky ND (January 1969). "Structure of lagochilin". Tetrahedron Letters. 10 (17): 1361–1364. doi:10.1016/S0040-4039(01)87886-2.
- ^ Chizhov OS, Kessenikh AV, Yakovlev IP, Zolotarev BM, Petukhov VA (1970). "The structure of lagochilin". Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 19 (9): 1866–1972. doi:10.1007/BF00849762.
