Idrocilamide
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Muscle relaxant
Pharmaceutical compound
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| Trade names | Talval, Srilane, Relaxnova, Brolitène |
| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Topical |
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| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.027.414 Edit this at Wikidata |
| Chemical and physical data | |
| Formula | C11H13NO2 |
| Molar mass | 191.230 g·mol−1 |
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Idrocilamide (trade names Talval, Srilane, Relaxnova, Brolitène[1] ) is a medication with skeletal muscle relaxant[2] and anti-inflammatory actions[3] used as a topical cream to treat lumbago and other kinds of muscular pain;[4] it is available on prescription or over-the-counter[citation needed ] in France and various other countries.[1]
Interactions
[edit ]Idrocilamide has been reported to be a potent inhibitor of the metabolism of caffeine.[5] [6]
References
[edit ]- ^ a b Drugs.com: International Drug Names
- ^ Bouron A, Rivet M, Nasri-Sebdani M, Guillemain J, Durbin P, Guerrier D, Raymond G (1990). "The direct depressant effect of LCB29 (idrocilamide) on mechanical tension of rat soleus muscle fibers". Canadian Journal of Physiology and Pharmacology . 68 (12): 1503–1509. doi:10.1139/y90-228. PMID 2085796.
- ^ Bannwarth B, Le Huec JC, Vinçon G, Labat L, Demotes-Mainard F, Rivaille F, Le Rebeller A (1993). "[Tissue and systemic diffusion of idrocilamide after cutaneous administration]". Revue du Rhumatisme (in French). 60 (12): 932–6. PMID 8012322.
- ^ Stehman M, Lehert P (1990). "Clinical double-blind study with idrocilamide ointment in the treatment of acute lumbago". Acta Belgica. Medica Physica . 13 (1): 29–32. PMID 2140002.
- ^ Carrillo JA, Benitez J (2000). "Clinically significant pharmacokinetic interactions between dietary caffeine and medications". Clinical Pharmacokinetics . 39 (2): 127–53. doi:10.2165/00003088-200039020-00004. PMID 10976659.
- ^ Brazier JL, Descotes J, Lery N, Ollagnier M, Evreux JC (1980). "Inhibition by idrocilamide of the disposition of caffeine". European Journal of Clinical Pharmacology . 17 (1): 37–43. doi:10.1007/bf00561675. PMID 7371698.
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