Jump to content
Wikipedia The Free Encyclopedia

GTF2F2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
GTF2F2
Identifiers
Aliases GTF2F2 , BTF4, RAP30, TF2F2, TFIIF, general transcription factor IIF subunit 2
External IDsOMIM: 189969; MGI: 1915955; HomoloGene: 37884; GeneCards: GTF2F2; OMA:GTF2F2 - orthologs
Available structures
PDB Ortholog search: PDBe RCSB
List of PDB id codes

1BBY, 1F3U, 2BBY, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6

Gene location (Human)
Chromosome 13 (human)
Chr. Chromosome 13 (human) [1]
Band 13q14.12-q14.13Start45,120,510 bp [1]
End45,284,893 bp [1]
Gene location (Mouse)
Chromosome 14 (mouse)
Chr. Chromosome 14 (mouse)[2]
Band 14|14 D3Start76,134,377 bp [2]
End76,248,305 bp [2]
RNA expression pattern
Bgee
Human Mouse (ortholog)
  • gonad

  • ventricular zone

  • ganglionic eminence

  • Achilles tendon

  • muscle of thigh

  • skin of abdomen

  • testicle

  • skin of leg

  • Skeletal muscle tissue of biceps brachii

  • gastrocnemius muscle
  • embryo

  • morula

  • morula

  • epiblast

  • embryo

  • uterus

  • lens

  • zygote

  • spermatid

  • cervix
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

2963

68705

Ensembl

ENSG00000188342

ENSMUSG00000067995

UniProt

P13984

Q8R0A0

RefSeq (mRNA)

NM_004128

NM_026816

RefSeq (protein)

NP_004119

NP_081092

Location (UCSC)Chr 13: 45.12 – 45.28 Mb Chr 14: 76.13 – 76.25 Mb
PubMed search[3] [4]
Wikidata

General transcription factor IIF subunit 2 is a protein that in humans is encoded by the GTF2F2 gene.[5] [6]

Interactions

[edit ]

GTF2F2 has been shown to interact with POLR2E [7] and HTATSF1.[8]

See also

[edit ]

References

[edit ]
  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000188342 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000067995 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Heng HH, Xiao H, Shi XM, Greenblatt J, Tsui LC (May 1994). "Genes encoding general initiation factors for RNA polymerase II transcription are dispersed in the human genome". Hum. Mol. Genet. 3 (1): 61–4. doi:10.1093/hmg/3.1.61. PMID 8162052.
  6. "Entrez Gene: GTF2F2 general transcription factor IIF, polypeptide 2, 38kDa".
  7. Wei W, Dorjsuren D, Lin Y, Qin W, Nomura T, Hayashi N, Murakami S (Apr 2001). "Direct interaction between the subunit RAP30 of transcription factor IIF (TFIIF) and RNA polymerase subunit 5, which contributes to the association between TFIIF and RNA polymerase II". J. Biol. Chem. 276 (15): 12266–73. doi:10.1074/jbc.M009634200 . PMID 11278533.
  8. Kim JB, Yamaguchi Y, Wada T, Handa H, Sharp PA (Sep 1999). "Tat-SF1 protein associates with RAP30 and human SPT5 proteins". Mol. Cell. Biol. 19 (9): 5960–8. doi:10.1128/mcb.19.9.5960. PMC 84462 . PMID 10454543.

Further reading

[edit ]
[edit ]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


Stub icon

This article on a gene on human chromosome 13 is a stub. You can help Wikipedia by adding missing information.

AltStyle によって変換されたページ (->オリジナル) /