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GNG13

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
GNG13
Identifiers
Aliases GNG13 , G(gamma)13, h2-35, G protein subunit gamma 13, HG3J
External IDsOMIM: 607298; MGI: 1925616; HomoloGene: 81890; GeneCards: GNG13; OMA:GNG13 - orthologs
Gene location (Human)
Chromosome 16 (human)
Chr. Chromosome 16 (human) [1]
Band 16p13.3Start798,041 bp [1]
End800,734 bp [1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr. Chromosome 17 (mouse)[2]
Band 17|17 A3.3Start25,936,145 bp [2]
End25,938,380 bp [2]
RNA expression pattern
Bgee
Human Mouse (ortholog)
  • right hemisphere of cerebellum

  • lateral nuclear group of thalamus

  • right frontal lobe

  • gonad

  • anterior cingulate cortex

  • Brodmann area 9

  • mucosa of transverse colon

  • prefrontal cortex

  • primary visual cortex

  • Amygdala
  • olfactory epithelium

  • lobe of cerebellum

  • neural layer of retina

  • cerebellar vermis

  • deep cerebellar nuclei

  • visual cortex

  • primary visual cortex

  • superior frontal gyrus

  • dentate gyrus of hippocampal formation granule cell

  • Temporal Lobe
More reference expression data
BioGPS
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

51764

64337

Ensembl

ENSG00000127588

ENSMUSG00000025739

UniProt

Q9P2W3

Q9JMF3

RefSeq (mRNA)

NM_016541

NM_022422
NM_001357782

RefSeq (protein)

NP_057625

NP_071867
NP_001344711

Location (UCSC)Chr 16: 0.8 – 0.8 Mb Chr 17: 25.94 – 25.94 Mb
PubMed search[3] [4]
Wikidata

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 is a protein that in humans is encoded by the GNG13 gene.[5] [6]

Interactions

[edit ]

GNG13 has been shown to interact with GNB5.[7]

References

[edit ]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000127588Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025739Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Huang L, Shanker YG, Dubauskaite J, Zheng JZ, Yan W, Rosenzweig S, Spielman AI, Max M, Margolskee RF (Jan 2000). "Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium". Nat Neurosci. 2 (12): 1055–62. doi:10.1038/15981. PMID 10570481. S2CID 24494794.
  6. ^ "Entrez Gene: GNG13 guanine nucleotide binding protein (G protein), gamma 13".
  7. ^ Blake BL, Wing MR, Zhou JY, Lei Q, Hillmann JR, Behe CI, Morris RA, Harden TK, Bayliss DA, Miller RJ, Siderovski DP (Dec 2001). "G beta association and effector interaction selectivities of the divergent G gamma subunit G gamma(13)". J. Biol. Chem. 276 (52): 49267–74. doi:10.1074/jbc.M106565200 . PMID 11675383.

Further reading

[edit ]
MAP
Calcium
G protein
Heterotrimeric
cAMP:
cGMP:
Monomeric
Cyclin
Lipid
Other protein kinase
Serine/threonine:
Tyrosine:
Serine/threonine/tyrosine
Arginine
Other protein phosphatase
Serine/threonine:
Tyrosine:
both:
Apoptosis
GTP-binding protein regulators
Other


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