GBP5

Protein-coding gene in humans

GBP5

Identifiers

GBP5 , GBP-5, guanylate binding protein 5

External IDs

OMIM: 611467; MGI: 2429943; HomoloGene: 14183; GeneCards: GBP5; OMA:GBP5 - orthologs

Gene location (Human)
Chromosome 1 (human)
Chr.	Chromosome 1 (human) ^[1]
Chromosome 1 (human) Genomic location for GBP5 Genomic location for GBP5
Band	1p22.2	Start	89,256,189 bp ^[1]
Band	1p22.2	End	89,272,860 bp ^[1]

Gene location (Mouse)
Chromosome 3 (mouse)
Chr.	Chromosome 3 (mouse)^[2]
Chromosome 3 (mouse) Genomic location for GBP5 Genomic location for GBP5
Band	3\|3 H1	Start	142,199,739 bp ^[2]
Band	3\|3 H1	End	142,228,105 bp ^[2]

RNA expression pattern

Bgee

Human	Mouse (ortholog)
Top expressed in granulocyte appendix monocyte blood lymph node spleen bone marrow cells gallbladder right uterine tube testicle	Top expressed in spleen urinary bladder thymus white adipose tissue jejunum ileum quadriceps femoris muscle bone marrow islet of Langerhans muscle tissue
More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	nucleotide binding GTP binding protein binding hydrolase activity GTPase activity identical protein binding protein homodimerization activity
Cellular component	cytoplasm Golgi membrane Golgi apparatus membrane cytoplasmic vesicle perinuclear region of cytoplasm
Biological process	immune system process positive regulation of cytokine production involved in inflammatory response inflammatory response positive regulation of NLRP3 inflammasome complex assembly protein homotetramerization positive regulation of innate immune response cellular response to interferon-gamma response to bacterium protein localization to Golgi apparatus
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


115362


229898

Ensembl


ENSG00000154451


ENSMUSG00000105504

UniProt


Q96PP8


Q8CFB4

RefSeq (mRNA)

NM_052942
NM_001134486
NM_001391920

NM_153564
NM_212440

RefSeq (protein)

NP_001127958
NP_443174

NP_705792

Location (UCSC)

Chr 1: 89.26 – 89.27 Mb

Chr 3: 142.2 – 142.23 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human View/Edit Mouse

Guanylate binding protein 5 is a protein in humans that is encoded by the GBP5 gene. ^[5]

References

[edit ]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000154451 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000105504 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Guanylate binding protein 5" . Retrieved 2013年01月23日.

GBP5

See also

References

Further reading