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DNAJB2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
DNAJB2
Available structures
PDB Ortholog search: PDBe RCSB
List of PDB id codes

2LGW

Identifiers
Aliases DNAJB2 , DSMA5, HSJ-1, HSJ1, HSPF3, CMT2T, DnaJ heat shock protein family (Hsp40) member B2
External IDsOMIM: 604139; MGI: 1928739; HomoloGene: 4902; GeneCards: DNAJB2; OMA:DNAJB2 - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr. Chromosome 2 (human) [1]
Band 2q35Start219,279,342 bp [1]
End219,286,898 bp [1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr. Chromosome 1 (mouse)[2]
Band 1|1 C4Start75,236,406 bp [2]
End75,245,692 bp [2]
RNA expression pattern
Bgee
Human Mouse (ortholog)
  • C1 segment

  • right hemisphere of cerebellum

  • right frontal lobe

  • anterior pituitary

  • Amygdala

  • cingulate gyrus

  • anterior cingulate cortex

  • prefrontal cortex

  • Brodmann area 9

  • tibial nerve
  • motor neuron

  • lens

  • spermatid

  • neural layer of retina

  • supraoptic nucleus

  • retinal pigment epithelium

  • spermatocyte

  • muscle of thigh

  • aortic valve

  • blood
More reference expression data
BioGPS
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

3300

56812

Ensembl

ENSG00000135924

ENSMUSG00000026203

UniProt

P25686

Q9QYI5

RefSeq (mRNA)

NM_006736
NM_001039550

NM_001159883
NM_001159884
NM_001159885
NM_020266
NM_178055

RefSeq (protein)

NP_001034639
NP_006727

NP_001153355
NP_001153356
NP_001153357
NP_064662
NP_835156

Location (UCSC)Chr 2: 219.28 – 219.29 Mb Chr 1: 75.24 – 75.25 Mb
PubMed search[3] [4]
Wikidata

DnaJ homolog subfamily B member 2 is a protein that in humans is encoded by the DNAJB2 gene.[5] [6] [7]

References

[edit ]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000135924Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026203Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Cheetham ME, Brion JP, Anderton BH (Jul 1992). "Human homologues of the bacterial heat-shock protein DnaJ are preferentially expressed in neurons". Biochem J. 284 ( Pt 2) (Pt 2): 469–76. doi:10.1042/bj2840469. PMC 1132662 . PMID 1599432.
  6. ^ Chapple JP, Hardcastle AJ, Kurzik-Dumke U, Collier DA, Cheetham ME (Oct 1999). "Assignment of the neuronal cochaperone, HSJ1, to human chromosome bands 2q32→q34 between D2S295 and D2S339 by in situ hybridization and somatic cell and radiation hybrids". Cytogenet Cell Genet. 86 (1): 62–3. doi:10.1159/000015411. PMID 10516435. S2CID 46545726.
  7. ^ "Entrez Gene: DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2".

Further reading

[edit ]
Chaperones/
protein folding
Heat shock proteins/
Chaperonins
Other
Protein targeting
Ubiquitin
(ubiquitylation)
Ubiquitin-like proteins
(UBL)
SUMO protein
(SUMOylation)
  • E2 SUMO-conjugating enzyme
Other


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