Cyclandelate

Chemical compound

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Pharmaceutical compound

Cyclandelate
Clinical data

AHFS/Drugs.com	Micromedex Detailed Consumer Information
ATC code	C04AX01 (WHO )
Identifiers
IUPAC name 3,3,5-trimethylcyclohexyl hydroxy(phenyl)acetate
CAS Number	456-59-7
PubChem CID	2893
DrugBank	DB04838 ^checkY
ChemSpider	2790 ^checkY
UNII	4139O1OAY2
KEGG	D00286 ^checkY
ChEBI	CHEBI:3988 ^checkY
ChEMBL	ChEMBL1480987
CompTox Dashboard (EPA)	DTXSID4022862 Edit this at Wikidata
ECHA InfoCard	100.006.611 Edit this at Wikidata
Chemical and physical data
Formula	C₁₇H₂₄O₃
Molar mass	276.376 g·mol⁻¹
3D model (JSmol)	Interactive image
Melting point	55 to 56.5 °C (131.0 to 133.7 °F)
Boiling point	192 to 194 °C (378 to 381 °F) (14 mmHg)
SMILES O=C(OC1CC(CC(C1)(C)C)C)C(O)c2ccccc2
InChI InChI=1S/C17H24O3/c1-12-9-14(11-17(2,3)10-12)20-16(19)15(18)13-7-5-4-6-8-13/h4-8,12,14-15,18H,9-11H2,1-3H3^checkY Key:WZHCOOQXZCIUNC-UHFFFAOYSA-N^checkY
(verify)

Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis and Raynaud's disease.^[1] It is also used to treat nighttime leg cramps, and has been investigated for its effect against migraine. It is orally administered.

References

^ Smith AL (January 1965). "Cyclandelate (Cyclospasmol) in the Treatment of Peripheral Circulatory Diseases". Angiology. 16: 1–7. doi:10.1177/000331976501600101. PMID 14258038.

v t e Peripheral vasodilators (C04)
Phenylethanolamine derivatives	Isoxsuprine Buphenine Bamethan
Alpha blockers	Non-selective Buflomedil Phentolamine Phenoxybenzamine Tolazoline Selective α₁-blockers Alfuzosin Doxazosin Prazosin Silodosin Tamsulosin Terazosin
Nicotinic acid and derivatives	Nicotinic acid Nicotinyl alcohol Inositol nicotinate Ciclonicate
Purine derivatives	Pentifylline Xantinol nicotinate Pentoxifylline Etofylline nicotinate
Ergot alkaloids	Ergoloid Nicergoline Dihydroergocristine
Other peripheral vasodilators	Cyclandelate Vincamine Moxisylyte Bencyclane Vinburnine Sulcotidil Naftidrofuryl Butalamine Visnadine Cetiedil Cinepazide Ifenprodil Azapetine Fasudil

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