Bromonordiazepam
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Pharmaceutical compound
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Bromonordiazepam, also known as Desalkylgidazepam, is a benzodiazepine derivative[1] which has been sold as a designer drug.[2] [3] It is structurally similar to diazepam, and its analogue nordazepam, but exchanges a chloro group at position 7 for a bromine substitution. It is the active metabolite of gidazepam,[4] but has appeared in the illicit drug market alone.[2] [5] [3] Its in-vitro potency is similar that of alprazolam,[6] while subjective effects are not yet reported.
See also
[edit ]References
[edit ]- ↑ "Desalkylgidazepam (CAS 2894-61-3)". Cayman. Retrieved 2026年06月08日.
- 1 2 "Bromonordiazepam found in 'Xanax' sample - The Know". The Know - Australian drug alerts, all in one place. 2023年09月12日. Retrieved 2026年06月08日.
- 1 2 Maskell PD, Wilson G, Manchester KR (April 2023). "Designer Benzodiazepines Gidazepam and Desalkygidazepam (Bromonordiazepam): What Do We Know?". Journal of Analytical Toxicology. 47 (4): 324–331. doi:10.1093/jat/bkad004. PMID 36695345.
- ↑ Andronati SA, Zin'kovskiĭ VG, Totrova MI, Golovenko NI, Stankevich EA, Zhuk OV (January 1992). "[Biokinetics of a new prodrug gidazepam and its metabolite]". Biulleten' Eksperimental'noi Biologii I Meditsiny. 113 (1): 45–47. PMID 1356504.
- ↑ Canada H (2023年12月15日). "Emergence of Desalkylgidazepam, a novel benzodiazepine in Canada". www.canada.ca. Retrieved 2026年06月08日.
- ↑ Norman C, Liin SI, Jauregi-Miguel A, Ottosson NE, Gréen H (April 2026). "In vitro γ-aminobutyric acid A (GABAA) receptor activity and binding interactions at the α+/γ2- interface of 53 prescription and designer benzodiazepines". Communications Chemistry. 9 (1) 155. Bibcode:2026CmChe...9..155N. doi:10.1038/s42004-026-02001-x. PMC 13068902 . PMID 41946818.
- ↑ Jeffers MR, Greer WR (6 June 2026). "Technical note: Identification of the novel benzodiazepine 3-hydroxy desalkylgidazepam within PSNI tablet seizures in northern Ireland". Journal of Forensic and Legal Medicine. 121 103187. doi:10.1016/j.jflm.2026.103187. PMID 42269423.