Benzquinamide

Chemical compound

"Quantril" redirects here. For the surname, see Quantrill.

Pharmaceutical compound

Benzquinamide
Clinical data

Trade names	Promecon, Quantril, Emete-Con
License data	US FDA: Quantril
Routes of administration	Suppository, injection
ATC code	none
Legal status
Legal status	BR: Class C1 (Other controlled substances)^[1]
Identifiers
IUPAC name 3-(Diethylcarbamoyl)-9,10-dimethoxy-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-yl acetate
CAS Number	63-12-7 ^checkY
IUPHAR/BPS	7124
DrugBank	DB00767 ^☒N
ChemSpider	2252 ^☒N
UNII	0475EA27Q3
KEGG	D00243 ^☒N
ChEMBL	ChEMBL1201250 ^☒N
CompTox Dashboard (EPA)	DTXSID9022657 Edit this at Wikidata
Chemical and physical data
Formula	C₂₂H₃₂N₂O₅
Molar mass	404.507 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCN(CC)C(=O)C1CN2CCc3cc(OC)c(OC)cc3C2CC1OC(=O)C
InChI InChI=InChI=1S/C22H32N2O5/c1-6-23(7-2)22(26)17-13-24-9-8-15-10-20(27-4)21(28-5)11-16(15)18(24)12-19(17)29-14(3)25/h10-11,17-19H,6-9,12-13H2,1-5H3^☒N Key:JSZILQVIPPROJI-UHFFFAOYSA-N^☒N
^☒NcheckY (what is this?) (verify)

Benzquinamide is a discontinued antiemetic drug used in post-operative care. It was first synthesised by Pfizer in the 1960s.^[2] ^[3]

References

^ Anvisa (2023年03月31日). "RDC No 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023年04月04日). Archived from the original on 2023年08月03日. Retrieved 2023年08月16日.
^ Scriabine A, Weissman A, Finger KF (1963). "Benzquinamide". JAMA. 184 (4): 276–279. doi:10.1001/jama.1963.73700170001010. ISSN 0098-7484. PMID 13992595.
^ E.I. Goldenthal (1971). "A compilation of LD50 values in newborn and adult animals". Toxicol. Appl. Pharmacol. 18 (1): 185–207. doi:10.1016/0041-008X(71)90328-0. PMID 5542824.

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