Benzilone

Chemical compound

Not to be confused with Benzylone.

Pharmaceutical compound

Benzilone
Clinical data

ATC code	A03AB01 (WHO )
Identifiers
IUPAC name 1,1-diethyl-3-(2-hydroxy-2,2-diphenylacetoxy)pyrrolidinium
CAS Number	16175-92-1 ^checkY 1050-48-2 (bromide)
PubChem CID	66248
ChemSpider	59632 ^☒N
UNII	GY56LQX77B
ChEMBL	ChEMBL2106061 ^☒N
CompTox Dashboard (EPA)	DTXSID40859574 Edit this at Wikidata
Chemical and physical data
Formula	C₂₂H₂₈NO₃
Molar mass	354.470 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(OC1CC[N+](CC)(CC)C1)C(O)(c2ccccc2)c3ccccc3
InChI InChI=1S/C22H28NO3/c1-3-23(4-2)16-15-20(17-23)26-21(24)22(25,18-11-7-5-8-12-18)19-13-9-6-10-14-19/h5-14,20,25H,3-4,15-17H2,1-2H3/q+1^☒N Key:ZKCWITXZGWUJAV-UHFFFAOYSA-N^☒N
^☒NcheckY (what is this?) (verify)

Benzilone is an antimuscarinic drug.^[1]^[2]

References

^ "Benzilone". KEGG database. Retrieved 9 May 2015.
^ Schwartz TW, Stenquist B, Olbe L, Stadil F (January 1979). "Synchronous oscillations in the basal secretion of pancreatic-polypeptide and gastric acid. Depression by cholinergic blockade of pancreatic-polypeptide concentrations in plasma". Gastroenterology. 76 (1): 14–9. doi:10.1016/s0016-5085(79)80121-3 . PMID 758136. Benzilonium bromide (Parke, Davis & Co., Detroit Mich.) is a quarternary antimuscarinic agent with minimal passage of the blood-brain barrier.

Tertiary amino group	Camylofin Dicycloverine Difemerine Dihexyverine Mebeverine Oxyphencyclimine Piperidolate Rociverine Trimebutine
Quaternary ammonium compounds	Benzilone Bevonium Diphemanil Fenpiverinium Glycopyrronium Hexocyclium Isopropamide Mepenzolate Methantheline Otilonium Oxyphenonium Penthienate Pipenzolate Poldine Prifinium Propantheline Tiemonium Timepidium Tridihexethyl