Aminomethylsulfonic acid
| Names | |
|---|---|
| IUPAC name
Aminomethanesulfonic acid | |
| Other names
Aminomethylenesulfonic acid | |
| Identifiers | |
3D model (JSmol) |
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| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.034.212 Edit this at Wikidata |
| EC Number |
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PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| CH5NO3S | |
| Molar mass | 111.12g·mol−1 |
| Appearance | White crystalline solid |
| Melting point | 190–194°C (374–381°F; 463–467K)[1] |
| Hazards | |
| GHS labelling: | |
| GHS05: Corrosive | |
| Danger | |
| H314 | |
| P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, P501 | |
| Related compounds | |
Related compounds |
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Except where otherwise noted, data are given for materials in their standard state (at 25°C [77°F], 100kPa).
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Aminomethylsulfonic acid (also called aminomethylenesulfonic acid and aminomethanesulfonic acid) is an organic chemical compound, with amino (−NH2) and sulfonic acid (−SO2−OH) groups on the carbon atom. Its chemical formula is N H 2CH2S O 2OH, and it has a molar mass of 111.12 g/mol.
Synthesis
[edit ]Aminomethane sulfonic acid can be made by the reaction between hexamethylenetetramine (hexamine) with sulfur dioxide (SO2) in an aqueous environment.[2]
Properties
[edit ]Aminomethanesulfonic acid is a corrosive solid. It could be thought of as the sulfonic acid analogue of glycine, just like aminomethylphosphonic acid is the phosphonic analogue of glycine.[3] Its density is ~1.7 g/cm3.[4]
Aminomethanesulfonic acid appears as a white crystalline solid that dissolves readily in water. It exhibits amphoteric behavior, meaning it can act as either an acid or a base depending on the conditions. Heating the compound above 280 °C leads to decomposition, releasing sulfur dioxide and other gaseous products.[5]
Uses
[edit ]Although aminomethanesulfonic acid has limited commercial use, it has been employed in research as a reagent and as a buffering agent. It has also been studied as a structural analog of taurine in biochemical research, helping to investigate metabolic pathways and sulfonic acid derivatives.[6]
Dangers
[edit ]Aminomethanesulfonic acid can cause skin and eye burns, it is an dermatotoxin.
References
[edit ]- ↑ "Aminomethanesulfonic acid (CAS RN: 13881-91-9)". CAS Common Chemistry. Chemical Abstracts Service . Retrieved 2026年01月15日.
- ↑ Khoma, R. E.; et al. (2019). "Synthesis, crystal structure, and spectral characteristics of N-(n-propyl) aminomethanesulfonic acid. Acute toxicity of aminomethanesulfonic acid and its N-alkylated derivatives". Voprosy Khimii i Khimicheskoi Tekhnologii. 6 (6): 255–262. doi:10.32434/0321-4095-2019-127-6-255-262 .
- ↑ CID 83791 from PubChem
- ↑ CSID:75612, https://www.chemspider.com/Chemical-Structure.75612.html, (accessed 16:39, Jan 15, 2026)
- ↑ Becker, K. (1974). "Thermal decomposition of aminomethanesulfonic acid and related sulfonic acids". Journal of Thermal Analysis. 7 (3): 311–318. doi:10.1007/BF01911590.
- ↑ Huxtable, R. (1982). "Taurine analogs and metabolic studies". Advances in Experimental Medicine and Biology. 141: 261–273. doi:10.1007/978-1-4684-8181-5_23.