2CT-5-EtO
| Clinical data | |
|---|---|
| Other names | 2CT-5EtO; 2CT-5-ETO; 2CT-5ETO; 4-Methylthio-2-methoxy-5-ethoxyphenethylamine; 2-Methoxy-4-methylthio-5-ethoxyphenethylamine |
| Routes of administration | Oral [1] [2] |
| Drug class | Serotonergic psychedelic; Hallucinogen |
| ATC code |
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| Pharmacokinetic data | |
| Duration of action | ~15 hours[1] [2] [3] |
| Identifiers | |
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| Chemical and physical data | |
| Formula | C12H19NO2S |
| Molar mass | 241.35g·mol−1 |
| 3D model (JSmol) | |
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2CT-5-EtO, also known as 2-methoxy-4-methylthio-5-ethoxyphenethylamine, is a psychedelic drug of the phenethylamine, 2C, and TWEETIO families related to 2C-T.[1] [2] [3] It is the derivative of 2C-T in which the methoxy group at the 5 position has been replaced with an ethoxy group.[1] [2] [3]
According to Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, 2CT-5-EtO's dose is 30mg orally and its duration is perhaps 15hours.[1] [2] [3] The effects of 2CT-5-EtO have been reported to include body awareness and modest closed-eye visuals, with the experience being described as quiet, peaceful, contemplative, and insightful.[1] Other effects included insomnia and lots of dreams during sleep.[1]
The chemical synthesis of 2CT-5-EtO has been described.[1]
2CT-5-EtO was first described in the literature by Shulgin in PiHKAL in 1991.[1] It was developed and tested by Darrell Lemaire, with publication via personal communication with Shulgin.[2] [4] [5] [6] [7] The drug is a controlled substance in Canada under phenethylamine blanket-ban language.[8]
See also
[edit ]References
[edit ]- 1 2 3 4 5 6 7 8 9 Shulgin A, Shulgin A (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. "The 5-EtO-homologue of 2C-T is 5-ethoxy-2-methoxy-4-methylthiophenethylamine, or 2CT-5ETO. The benzaldehyde (5-ethoxy-2-methoxy-4-(methylthio)benzaldehyde) was impure, and had a melting point of about 66 °C, the nitrostyrene intermediate a melting point of 133–134 °C, and the final hydrochloride a melting point of 184–185 °C. There was a body awareness and modest eyes-closed visuals following the use of 30 milligrams of 2CT-5ETO. The experience was quiet, peaceful, contemplative, and insightful. The duration was perhaps 15 hours and Halcion was needed to allow sleep. There were a lot of dreams, and the next day was restful."
- 1 2 3 4 5 6 Shulgin AT (2003). "Basic Pharmacology and Effects". In Laing RR (ed.). Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. pp. 67–137. ISBN 978-0-12-433951-4. Archived from the original on 13 July 2025.
- 1 2 3 4 Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German) (1 ed.). Solothurn: Nachtschatten-Verlag. ISBN 978-3-03788-700-4. OCLC 858805226. Archived from the original on 21 August 2025.
- ↑ "Erowid Darrell Lemaire Vault". erowid.org. Retrieved 14 November 2025.
- ↑ Morris H (7 December 2016). "The Lazy Lizard School of Hedonism". Hamilton's Pharmacopeia . Season 1. Episode 6. Vice Media. Viceland.
- ↑ Nez H, Lemaire D (2010). "Notes About Psychoactive Compounds" (PDF). In Targ R, Radin D (eds.). Radiant Minds: Scientists Explore the Dimensions of Consciousness. Millay. pp. 201–207. ISBN 978-0-615-29633-3.
- ↑ Nez H, Lemaire D (Lazar) (1990). Certain Exotic Transmitters as Smart Pills or Compounds that Increase the Capacity for Mental Work in Humans: A Story About LAZAR as Told by Hosteen Nez (2nd ed.). Archived from the original (PDF) on 9 July 2001.
- ↑ "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.