2CB-2,5-DiEtO
| Clinical data | |
|---|---|
| Other names | 2CB-DiEtO; 2CB-Di-EtO; 2CB-DIETO; 2CB-DI-ETO; 2,5-Diethoxy-4-bromophenethylamine; 4-Bromo-2,5-diethoxyphenethylamine |
| Routes of administration | Oral [1] [2] [3] |
| Drug class | Psychoactive drug |
| ATC code |
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| Pharmacokinetic data | |
| Duration of action | Unknown[1] [2] [3] |
| Identifiers | |
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| Chemical and physical data | |
| Formula | C12H18BrNO2 |
| Molar mass | 288.185g·mol−1 |
| 3D model (JSmol) | |
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2CB-2,5-DiEtO, also known as 2,5-diethoxy-4-bromophenethylamine, is a psychoactive drug of the phenethylamine, 2C, and TWEETIO families related to the psychedelic drug 2C-B.[1] [2] [3] It is the derivative of 2C-B in which the methoxy groups at the 2 and 5 positions have been replaced with ethoxy groups.[1] [2] [3]
According to Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, 2CB-2,5-DiEtO's dose is greater than 55mg orally and its duration is unknown.[1] [2] [3] The effects of 2CB-2,5-DiEtO have been reported to include only restless sleep and strange dreams.[1] [2] [3] Per Shulgin, no clear active dose level of 2CB-2,5-DiEtO has yet been found.[1]
The chemical synthesis of 2CB-2,5-DiEtO has been described.[1]
2CB-2,5-DiEtO was first described in the literature by Shulgin in PiHKAL in 1991.[1] It was developed and tested by Darrell Lemaire, with publication via personal communication with Shulgin.[2] [4] [5] [6] [7] The drug is a controlled substance in Canada under phenethylamine blanket-ban language.[8]
See also
[edit ]References
[edit ]- 1 2 3 4 5 6 7 8 9 Shulgin A, Shulgin A (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. "The 2,5-DiEtO- homologue of 2C-B is 4-bromo-2,5-diethoxyphenethylamine, or 2CB-2,5-DIETO. The unbrominated impure benzaldehyde (2,5-diethoxybenzaldehyde) had a melting point of about 57 °C, the unbrominated impure nitrostyrene intermediate a melting point of about 60 °C, and the final hydrochloride a melting point of 230–231 °C. The hydrobromide salt had a melting point of 192–193 °C. At levels of 55 milligrams, there was only a restless sleep, and strange dreams. The active level is not yet known."
- 1 2 3 4 5 6 7 Shulgin AT (2003). "Basic Pharmacology and Effects". In Laing RR (ed.). Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. pp. 67–137. ISBN 978-0-12-433951-4. Archived from the original on 13 July 2025.
- 1 2 3 4 5 6 Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German) (1 ed.). Solothurn: Nachtschatten-Verlag. ISBN 978-3-03788-700-4. OCLC 858805226. Archived from the original on 21 August 2025.
- ↑ "Erowid Darrell Lemaire Vault". erowid.org. Retrieved 14 November 2025.
- ↑ Morris H (7 December 2016). "The Lazy Lizard School of Hedonism". Hamilton's Pharmacopeia . Season 1. Episode 6. Vice Media. Viceland.
- ↑ Nez H, Lemaire D (2010). "Notes About Psychoactive Compounds" (PDF). In Targ R, Radin D (eds.). Radiant Minds: Scientists Explore the Dimensions of Consciousness. Millay. pp. 201–207. ISBN 978-0-615-29633-3.
- ↑ Nez H, Lemaire D (Lazar) (1990). Certain Exotic Transmitters as Smart Pills or Compounds that Increase the Capacity for Mental Work in Humans: A Story About LAZAR as Told by Hosteen Nez (2nd ed.). Archived from the original (PDF) on 9 July 2001.
- ↑ "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.