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MungeSumstats

This is the released version of MungeSumstats; for the devel version, see MungeSumstats.

Standardise summary statistics from GWAS


Bioconductor version: Release (3.22)

The *MungeSumstats* package is designed to facilitate the standardisation of GWAS summary statistics. It reformats inputted summary statisitics to include SNP, CHR, BP and can look up these values if any are missing. It also pefrorms dozens of QC and filtering steps to ensure high data quality and minimise inter-study differences.

Author: Alan Murphy [aut, cre] ORCID iD ORCID: 0000-0002-2487-8753 , Brian Schilder [aut, ctb] ORCID iD ORCID: 0000-0001-5949-2191 , Nathan Skene [aut] ORCID iD ORCID: 0000-0002-6807-3180

Maintainer: Alan Murphy <alanmurph94 at hotmail.com>

Citation (from within R, enter citation("MungeSumstats")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
 install.packages("BiocManager")
BiocManager::install("MungeSumstats")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MungeSumstats")
docker HTML R Script
MungeSumstats HTML R Script
OpenGWAS HTML R Script
Reference Manual PDF
NEWS Text

Details

Version 1.18.0
In Bioconductor since BioC 3.13 (R-4.1) (4.5 years)
License Artistic-2.0
Depends R (>= 4.1)
Imports data.table, utils, R.utils, dplyr, stats, GenomicRanges, GenomeInfoDb, IRanges, ieugwasr (>= 1.0.1), BSgenome, Biostrings, stringr, VariantAnnotation, methods, parallel, rtracklayer(>= 1.59.1), RCurl
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Package Archives

Follow Installation instructions to use this package in your R session.

Windows Binary (x86_64) MungeSumstats_1.18.0.zip
macOS Binary (x86_64) MungeSumstats_1.18.0.tgz
macOS Binary (arm64) MungeSumstats_1.18.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/MungeSumstats
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/MungeSumstats
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