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Macarron

This is the released version of Macarron; for the devel version, see Macarron.

Prioritization of potentially bioactive metabolic features from epidemiological and environmental metabolomics datasets


Bioconductor version: Release (3.22)

Macarron is a workflow for the prioritization of potentially bioactive metabolites from metabolomics experiments. Prioritization integrates strengths of evidences of bioactivity such as covariation with a known metabolite, abundance relative to a known metabolite and association with an environmental or phenotypic indicator of bioactivity. Broadly, the workflow consists of stratified clustering of metabolic spectral features which co-vary in abundance in a condition, transfer of functional annotations, estimation of relative abundance and differential abundance analysis to identify associations between features and phenotype/condition.

Author: Amrisha Bhosle [aut], Ludwig Geistlinger [aut], Sagun Maharjan [aut, cre]

Maintainer: Sagun Maharjan <sagunmaharjann at gmail.com>

Citation (from within R, enter citation("Macarron")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
 install.packages("BiocManager")
BiocManager::install("Macarron")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

Version 1.13.2
In Bioconductor since BioC 3.15 (R-4.2) (3.5 years)
License MIT + file LICENSE
Depends R (>= 4.2.0), SummarizedExperiment
System Requirements
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Suggests knitr, BiocStyle, optparse, testthat (>= 2.1.0), rmarkdown, markdown
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64) Macarron_1.13.2.zip
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/Macarron
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/Macarron
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