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ClustIRR
This is the released version of ClustIRR; for the devel version, see ClustIRR.
Clustering of immune receptor repertoires
Bioconductor version: Release (3.22)
ClustIRR analyzes repertoires of B- and T-cell receptors. It starts by identifying communities of immune receptors with similar specificities, based on the sequences of their complementarity-determining regions (CDRs). Next, it employs a Bayesian probabilistic models to quantify differential community occupancy (DCO) between repertoires, allowing the identification of expanding or contracting communities in response to e.g. infection or cancer treatment.
Author: Simo Kitanovski [aut, cre] ORCID iD ORCID: 0000-0003-2909-5376 , Kai Wollek [aut] ORCID iD ORCID: 0009-0008-5941-9160
Maintainer: Simo Kitanovski <simokitanovski at gmail.com>
citation("ClustIRR")):
Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("ClustIRR")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("ClustIRR")
Details
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Package Archives
Follow Installation instructions to use this package in your R session.