To install this package, start R and enter:
## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("PAA")
In most cases, you don't need to download the package archive at all.
This package is for version 3.2 of Bioconductor; for the stable, up-to-date release version, see PAA.
Bioconductor version: 3.2
PAA imports single color (protein) microarray data that has been saved in gpr file format - esp. ProtoArray data. After pre-processing (background correction, batch filtering, normalization) univariate feature pre-selection is performed (e.g., using the "minimum M statistic" approach - hereinafter referred to as "mMs"). Subsequently, a multivariate feature selection is conducted to discover biomarker candidates. Therefore, either a frequency-based backwards elimination aproach or ensemble feature selection can be used. PAA provides a complete toolbox of analysis tools including several different plots for results examination and evaluation.
Author: Michael Turewicz [aut, cre], Martin Eisenacher [ctb, cre]
Maintainer: Michael Turewicz <michael.turewicz at rub.de>, Martin Eisenacher <martin.eisenacher at rub.de>
Citation (from within R,
enter citation("PAA")):
To install this package, start R and enter:
## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("PAA")
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("PAA")
Follow Installation instructions to use this package in your R session.
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