We recently found that diisopropylamine dichloroacetate (DADA), which is the active component of pangamic acid ["vitamin B15", Liverall[R] (Daiichi Sankyo Co., Tokyo, Japan)] (50) and has been used for over 50 years for the treatment of chronic liver diseases without any adverse reaction, is a selective and safe inhibitor of PDK4.
One example experts cite is the vitamin that isn't pangamic acid, a substance isolated from apricot pits and represented as "vitamin B-15." It's promoted as a cure for heart disease, diabetes, glaucoma, alcoholism, liver disease and arthritis.