dromotropic

Recent several studies have pointed the efficiency of Calcium channel blockers like Diltiazem by virtue of their properties, direct vasodilation and negative chronotropic and dromotropic effects.8910 Therefore, comparison of the effects of intravenous Diltiazem and intravenous Lignocaine, a more commonly used agent, on blunting the pressor responses to endotracheal intubation was done in our study.

[beta]-Blockers and calcium channel blockers are the basic drugs which are utilize for the heart rate reduction, but their negative inotropic and dromotropic effects restrict their utilization in patients with hypotension, asthma, and peripheral vascular disease as some patients cannot bear the side effects2.

It had a negative chronotropic effect through suppression of the automaticity of cardiac pacemakers and a negative dromotropic effect on the inhibition of AVB [8].

High doses of cardiotoxic glycosides cause a substantial decrease in conduction rate, called negative dromotropic effect, resulting in severe atrium-ventricular dissociation, with consequent first-, second-, and third-degree blockade.

The patient's symptoms continued to occur over the course of the next few days, despite the discontinuation of all potential medications with chronotropic and/or dromotropic effects.

Dai and Xu reported that the effects of an ethanol extract of the plant Sophora flavescens Ait possessed antiarrhythmic activity which mechanisms maybe related with a dose dependant negative chronotropic, negative automatotropic and negative dromotropic effect (Dai et al.

Rate control is achieved by dromotropic drugs (e.g.

However, when ISO, a nonselective beta-adrenergic agonist that induces positive chronotropic, dromotropic, and inotropic effects, was employed to mimic the activation of cardiac sympathetic nerve system, diabetic rats showed a prominent depression of LVDP and the maximum rate of contraction and relaxation ([+ or -] dp/dt) due to DCM compared with those of normal rats.

Selective beta-1 receptor antagonists have negative chronotropic, dromotropic, and bathmotropic effects, slowing heart rate, delaying conduction in the atrioventricular node, and reducing myocardial excitability, respectively.