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Dictyostelium Mutants

Phenotypes for Dictyostelium mutants

View other mutant types: All mutant strains - Null - Overexpression - Multiple - Other - Developmental

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Systematic Name Strain Descriptor Associated gene(s) Phenotypes
DBS0350059 mcln-mclnaberrant cellular response to fluid shear stress | increased growth rate | aberrant post-lysosomal vacuole exocytosis
DBS0351382 myoB-/ [act15]: GFP: myoB(1-921,1057-1111)myoBabolished protein localization to actin wave
DBS0350826 pinA-pinAdecreased growth rate | decreased mound size | decreased sporulation
DBS0235412 1C7gp130decreased cell-substrate adhesion | delayed development | increased growth rate
DBS0238601 5NT-5ntdelayed development of tipped mound | increased number of mound tips | increased number of early culminant tips
DBS0235584 CF45-1-cf45-1increased mound size | increased glucose level | decreased mound size | decreased cell motility | increased cell-cell adhesion
DBS0235585 CF50-cf50-1 | cf50-2decreased response to Gram-negative bacterium | decreased response to Gram-positive bacterium | increased mound size | increased cell-cell adhesion | increased prespore gene expression | increased protein level | decreased protein secretion
DBS0235596 ChLim-ChLimincreased growth rate | increased phagocytosis
DBS0351197 D2B-D2Baberrant chemotaxis to cAMP
DBS0235659 DD3-3-DD3-3decreased gene expression | precocious aggregation
DBS0236049 DDB_G0268012-DDB_G0268012wild type
DBS0236046 DDB_G0268158-DDB_G0268158wild type
DBS0236039 DDB_G0268678-DDB_G0268678wild type
DG1007 DDB_G0269232-DDB_G0269232abolished culmination
DBS0236025 DDB_G0270366-DDB_G0270366wild type
DBS0236026 DDB_G0270368-DDB_G0270368wild type
DBS0236036 DDB_G0270744-DDB_G0270744wild type
DBS0351081 DDB_G0272538-DDB_G0272538delayed aggregation | increased cell-substrate adhesion
LAS29 DDB_G0273201-DDB_G0273201decreased socially cooperative development
LAS8 DDB_G0273809-zplC-1 | zplC-2decreased socially cooperative development
LAS43 DDB_G0274429-DDB_G0274429decreased socially cooperative development
DBS0351079 DDB_G0274679-DDB_G0274679delayed aggregation | increased cell-substrate adhesion | decreased cell motility
DBS0236043 DDB_G0276221-fam21wild type
DBS0236042 DDB_G0276689-DDB_G0276689wild type
DBS0236041 DDB_G0277179-DDB_G0277179wild type
LAS26 DDB_G0277239-DDB_G0277239decreased socially cooperative development
DBS0236045 DDB_G0277575-DDB_G0277575wild type
DBS0236044 DDB_G0278315-DDB_G0278315wild type
LAS34 DDB_G0278585-DDB_G0278585decreased socially cooperative development
DBS0236038 DDB_G0279005-cnot11wild type
DBS0236032 DDB_G0279163-DDB_G0279163wild type
DBS0236033 DDB_G0279163-DDB_G0279163wild type
LAS70 DDB_G0279405-DDB_G0279405decreased socially cooperative development
DBS0236028 DDB_G0279609-DDB_G0279609wild type
DBS0236029 DDB_G0279609-DDB_G0279609wild type
LAS103 DDB_G0280089-DDB_G0280089decreased socially cooperative development
LAS54 DDB_G0280299-DDB_G0280299decreased socially cooperative development
DBS0236035 DDB_G0280481-DDB_G0280481wild type
DBS0351082 DDB_G0281485-DDB_G0281485delayed aggregation | increased cell-substrate adhesion | decreased cell motility
DBS0351080 DDB_G0281497-DDB_G0281497delayed aggregation | increased cell-substrate adhesion | decreased cell motility
DBS0236019 DDB_G0281735-DDB_G0281735wild type
DBS0236020 DDB_G0281735-DDB_G0281735wild type
LAS92 DDB_G0283373-DDB_G0283373decreased socially cooperative development
LAS106 DDB_G0283595-DDB_G0283595decreased socially cooperative development
DBS0351085 DDB_G0284955-DDB_G0284955delayed aggregation | increased cell-substrate adhesion | decreased cell motility
LAS3 DDB_G0287153-DDB_G0287153decreased socially cooperative development
LAS10 DDB_G0288547-DDB_G0288547decreased socially cooperative development
LAS9 DDB_G0289789-DDB_G0289789decreased socially cooperative development
DBS0236027 DDB_G0290225-DDB_G0290225wild type
DBS0351086 DDB_G0290519-DDB_G0290519delayed aggregation | increased cell-substrate adhesion | decreased cell motility
LAS7 DDB_G0290685-DDB_G0290685decreased socially cooperative development
DG1003 DDB_G0291992-DDB_G0291992aberrant late culminant morphology
LAS39 DDB_G0292148-DDB_G0292148decreased socially cooperative development
DBS0236037 DDB_G0292186-DDB_G0292186wild type
DBS0350073 DDB_G0293074-DDB_G0293074decreased spore germination | delayed aggregation
DBS0351083 DDB_G0293098-DDB_G0293098delayed aggregation | increased cell-substrate adhesion | decreased cell motility
DBS0236023 DDB_G0293116-DDB_G0293116wild type
DBS0236024 DDB_G0293116-DDB_G0293116wild type
DBS0350516 DDB_G0293356-DDB_G0293356decreased defense response to Gram-negative bacterium
DBS0236030 DDB_G0293762-DDB_G0293762wild type
DG1039 DG1039-DDB_G0284037aberrant fruiting body morphogenesis
DG1040 DG1040-DDB_G0276029aberrant fruiting body morphogenesis
DG1041 DG1041-DDB_G0269126aberrant fruiting body morphogenesis
DG1054 DG1054-DDB_G0277719aberrant fruiting body morphogenesis
DG1060 DG1060-DDB_G0281953aberrant fruiting body morphogenesis
DG1062 DG1062-cdl1Aaberrant fruiting body morphogenesis
DG1074 DG1074-DDB_G0272108aberrant fruiting body morphogenesis
DG1080 DG1080-DDB_G0281559aberrant fruiting body morphogenesis
DG1091 DG1091-DG1091decreased fruiting body size
DG1098 DG1098-DG1098decreased fruiting body size
DG1104 DG1104-DDB_G0283535abolished aggregation
DG1106 DG1106-keaAabolished aggregation
DG1110 DG1110-DDB_G0269128aberrant fruiting body morphogenesis
DG1112 DG1112-DG1112decreased stalk width
DG1113 DG1113-DG1113increased stalk length
DG1122 DG1122-DG1122aberrant fruiting body morphogenesis
DG1124 DG1124-DG1124development arrests at loose mound stage
DG2033 DG2033-DG2033development arrests at mound stage
DG2044 DG2044-DG2044development arrests at loose mound stage
DBS0266700 Dd5P1-Dd5P1increased chemotaxis to cAMP | decreased phagocytosis
DBS0235660 Dd5P2-Dd5P2increased chemotaxis to cAMP | increased actin filament polymerization
DBS0266702 Dd5P3-Dd5P3wild type
DBS0266692 Dd5P4-Dd5P4increased protein localization | increased protein phosphorylation | increased contractile vacuole size | decreased defense response to Gram-negative bacterium | increased number of mound tips | aberrant contractile vacuole discharge | decreased growth rate | decreased phagocytosis | decreased engulfment during phagocytosis | aberrant endosome morphology | aberrant vacuole organization | decreased protein localization | increased cell motility | increased activation of GTPase activity
DBS0266693 Dd5P4-/ [act15]: Dd5P4Dd5P4wild type
DBS0266719 Dd5P4-/ [act15]: Dd5P4: GFPDd5P4wild type
DBS0266695 Dd5P4-/ [act15]: GAP5P4Dd5P4increased number of mound tips | decreased growth rate
DBS0351414 Dd5P4-/ [act15]: GFP: Dd5P4(D319G)Dd5P4increased contractile vacuole size | aberrant contractile vacuole discharge | aberrant protein localization to contractile vacuole
DBS0266720 Dd5P4-/ [act15]: Hs-OCRLDd5P4decreased phagocytosis
DBS0266721 Dd5P4-/ [act15]: Hs-OCRL(D422A)Dd5P4decreased phagocytosis
DBS0266694 Dd5P4-/ [act15]: cat5P4Dd5P4increased number of mound tips | decreased growth rate
DBS0351050 DidioMp27-DidioMp27decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis
DBS0351049 DidioMp36-DidioMp36decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis
DBS0236015 GEG04K11 (tmcB- in KAX3)tmcBdecreased macrocyst size | aberrant macrocyst formation
DBS0236017 GEG10K23 (tmcC- in KAX3)tmcCaberrant macrocyst formation
DBS0302615 GFP: phgA(1-274: 283-438)/ phgA-phgAaberrant hypotonic response
DBS0302614 GFP: phgA/ phgA-phgAwild type
DBS0236085 GP138C-cfrCwild type
AP1 HSPC300-hspc300aberrant cytokinesis
AP2 HSPC300-hspc300decreased actin filament polymerization | decreased cell motility | decreased vegetative cell size | decreased phototaxis | decreased pseudopodium size
DBS0351312 HSPC300-/ [act15]: abpB(129-295)abpB | hspc300aberrant cellular process
HTY506 HTY506pkaRaberrant spore morphology | precocious sporulation | aberrant fruiting body morphogenesis | decreased actin phosphorylation | precocious development | decreased cAMP level | decreased sporulation
DBS0236426 I6KA-I6KAaberrant cellular homeostasis | aberrant inositol phosphate metabolic process | increased growth rate
DBS0236840 R7nosAdevelopment arrests at mound stage
DBS0304456 [AS]alrA/ gcsA-alrA | gcsAaberrant cellular metabolic process | increased gene expression | decreased growth rate | mitotic G1 phase arrest
DBS0236827 [AS]proA/ proB-proA | proBdecreased exocytosis | decreased pinocytosis | aberrant exocytosis | increased actin filament polymerization | development arrests at slug stage | aberrant cytokinesis | decreased cell motility | abolished vegetative growth | decreased secretion of lysosomal enzymes | increased phagocytosis
DBS0238036 [AS]proA/ proB-/ [act15]: proAproA | proBwild type
DBS0238037 [AS]proA/ proB-/ [act15]: proBproA | proBwild type
DBS0302658 [act15]: cnrN: myc/ smlA-cnrN | smlAdecreased fruiting body size
DBS0304457 [act15]: sodA/ gcsA-gcsA | sodAwild type
DBS0304460 [act]: alrA/ gcsA-alrA | gcsAwild type
DBS0235407 [carA]: carA(1-317)carA-1 | carA-2delayed development
DBS0350696 [pkaC]: pkaC/ srfA-pkaC | srfAaberrant spore coat morphology | aberrant gene expression
DBS0351463 [tet]rasD(G12T)/ rigA-rasD | rigAwild type
HAD186 aarA-aarAaberrant stalk morphogenesis | aberrant Golgi localization | aberrant epithelium-like organization | decreased prespore gene expression | aberrant centrosome localization | aberrant stalk development | aberrant establishment or maintenance of cell polarity | decreased sporulation
DBS0349920 aarA-/ [act15]: GFP-mhcAaarAaberrant stalk morphogenesis | aberrant protein localization
DBS0351078 abcG6-abcG6delayed aggregation | increased cell-substrate adhesion | decreased cell motility
DBS0266687 abiA-abiAabolished protein localization to pseudopodium | decreased protein level | aberrant cytokinesis | decreased growth rate | decreased chemotaxis to folate
DBS0266688 abiA-abiAabolished protein localization to pseudopodium
DBS0351531 abiA-/ AX2abiAabolished protein localization to pseudopodium | decreased migratory slug size | aberrant filopodium formation | aberrant macropinocytosis | decreased cell motility | aberrant pseudopodium formation | decreased fruiting body size
DBS0350386 abiA-/ abiA(45-136)abiAdecreased protein level | aberrant cytokinesis
DBS0350384 abiA-/ abiA(45-332)abiAaberrant cytokinesis
DBS0351065 abnC-abnCdelayed aggregation | increased cell-substrate adhesion | decreased cell motility
DBS0235459 abpA-abpAaberrant hyperosmotic response
DBS0305672 abpB-abpBincreased filopodium formation
HG1264 abpC-abpCaberrant actin cytoskeleton organization
DBS0350936 abpC-abpCaberrant cortical actin cytoskeleton organization | decreased phagocytosis | decreased cell motility | decreased chemotaxis to cAMP | aberrant pseudopodium formation | decreased establishment of cell polarity
DBS0236077 abpC-abpCdecreased response to Gram-negative bacterium | aberrant thermotaxis | aberrant cortical actin cytoskeleton organization | decreased cell motility | aberrant phototaxis | decreased establishment of cell polarity | aberrant actin filament polymerization
DBS0237938 abpC-/ [act15]: GFP: abpC(9-148)abpCaberrant phototaxis
DBS0235426 abpC-/ [act15]: abpCabpCwild type
DBS0350938 abpC-/ [act15]: abpCabpCwild type
DBS0237945 abpC-/ [act15]: abpC(1-348: 449-857): GFPabpCaberrant phototaxis | aberrant actin filament organization
DBS0237946 abpC-/ [act15]: abpC(1-556: 644-857): GFPabpCaberrant phototaxis | aberrant actin filament organization
DBS0237941 abpC-/ [act15]: abpC(1-739): GFPabpCaberrant phototaxis
DBS0351553 abpC-/ [act15]: qkgA(425-1553)abpC | qkgA-1 | qkgA-2aberrant actin filament polymerization
DBS0237949 abpC-/ [cotB]: abpC: GFPabpCaberrant phototaxis
DBS0237948 abpC-/ [ecmA]: abpC: GFPabpCwild type
DBS0235427 abpD-abpDdecreased cell-cell adhesion | decreased spore germination | aberrant sorocarp development | delayed development
DBS0235428 abpE-abpE-1 | abpE-2increased lateral pseudopodium formation
DBS0349851 abpE-abpE-1 | abpE-2aberrant phagosome maturation | precocious phagosome acidification | increased phagocytosis
DBS0349852 abpE-/ [act15]: abpEabpE-1 | abpE-2decreased phagocytosis
DBS0350529 abpG-abpGincreased actin filament polymerization | decreased chemotaxis to cAMP | decreased fruiting body size
DBS0235562 acaA-acaAabolished stream development | abolished gene expression | abolished establishment of cell polarity | decreased gene expression | increased cellular thermotolerance | abolished aggregation | decreased adenylate cyclase activity | decreased cAMP level
GP6 acaA-acaAincreased lateral pseudopodium formation | decreased chemotaxis rate | aberrant actin filament organization | aberrant cell morphology | increased protein kinase activation
DBS0235429 acaA-acaAdecreased gene expression | abolished oscillatory cAMP signaling
DBS0350720 acaA-/ [acaA-agg]: acaA: mycacaAdecreased gene expression | decreased fruiting body size
DBS0350721 acaA-/ [acaA-psp]: acaA: mycacaAdecreased gene expression | decreased mound size | decreased fruiting body size
DBS0350722 acaA-/ [acaA-pst]: acaA: mycacaAwild type
DBS0350702 acaA-/ [act15]: HA: pkaCacaA | pkaCwild type | delayed development | decreased cAMP level
DBS0350737 acaA-/ [act15]: acaAacaAaberrant slug development
DBS0350738 acaA-/ [act15]: acaA(1-390;398-1407)acaAabolished aggregation
DBS0350739 acaA-/ [act15]: acaA(L394T/ K482N)acaAwild type
DBS0350603 acaA-/ [act15]: cap: GFPacaA | capdevelopment arrests at loose mound stage | increased calcium-dependent cell-cell adhesion | wild type
DBS0350735 acaA-/ [act15]: pkaR(G135E/ G261A)acaA | pkaRincreased cAMP level
DBS0350736 acaA-/ [unk]: acaA(F306L/ S498G,K504E,E593V,I649T)acaAdecreased gene expression | abolished oscillatory cAMP signaling | decreased cAMP level
DBS0350734 acaA-/ [unk]: acaA(N333D,G633S)acaAabolished adenylate cyclase activity
DBS0350733 acaA-/ [unk]: acaA(V427I,S642F)acaAabolished activation of adenylate cyclase activity
DBS0350711 acaA-/ [unk]: acgAacaA | acgAaberrant sorocarp development
DBS0306125 acapA-acapAwild type
DBS0350051 acapA-acapAaberrant exocytosis | aberrant filopodium formation | increased defense response to Gram-negative bacterium | aberrant endocytosis | aberrant cytokinesis | aberrant stream morphology | decreased cell motility | delayed development | aberrant lysosome organization
DBS0350055 acapA-/ [act15]: acapA(R633Q): GFPacapAaberrant filopodium formation | aberrant lysosome organization
DBS0350054 acapA-/ [act15]: acapA: GFPacapAincreased filopodium formation
DBS0306127 acapB-acapBwild type
TL177 acbA-acbAdecreased response to Gram-negative bacterium | abolished cell migration to prestalk region | abolished spore cell differentiation | decreased sporulation | decreased resistance to cisplatin
DBS0350194 acbA-/ [act15]: acbA(Y72A)acbAabolished spore cell differentiation
DBS0235440 acgA-acgAabolished polyketide metabolic process | decreased spore germination | decreased spore cell differentiation | precocious spore germination | abolished response to biotic stimulus
DBS0237788 acgA-acgAdecreased prespore cell differentiation | decreased prespore gene expression
DBS0237790 acgA-/ [acrA]: lacZacgA | acrAaberrant prestalk gene expression
DG1100 acrA-acrAdecreased gene expression | increased stalk length | decreased prespore gene expression | decreased sporulation
DBS0349939 acrA-acrAaberrant spore coat morphology | decreased stalk width
DBS0350723 acrA-/ [act15]: acaA(L394S)acaA | acrAprecocious spore germination
DBS0237786 acrA-/ [act15]: acgA(1-401)acgA | acrAdecreased prespore gene expression | decreased prespore cell differentiation | decreased sporulation
DBS0349970 acrA-/ [act15]: acrA(D1010A)acrAdecreased adenylate cyclase activity
DBS0349971 acrA-/ [act15]: acrA(D1174A)acrAincreased adenylate cyclase activity
DBS0349969 acrA-/ [act15]: acrA(N796D/ D854A/ G856A)acrAwild type
DBS0350724 acrA-/ [pkaC]: pkaCacrA | pkaCdecreased spore germination | decreased fruiting body size | precocious development | decreased sporulation
DBS0350443 adcB-adcBwild type
DBS0350444 adcC-adcCwild type
DBS0351190 adcC-/ [act15]: adcC(1-485)adcCdecreased protein localization to plasma membrane
DBS0351189 adcC-/ [act15]: adcC(101-654): GFPadcCabolished protein localization to plasma membrane
DBS0350538 adprt1A-adprt1Adecreased resistance to phleomycin | decreased double-strand break repair via nonhomologous end joining
DBS0351248 adprt1A-adprt1Adecreased gene expression | increased gene expression | decreased ATP level | delayed mitotic cell cycle | decreased growth rate | delayed aggregation | increased prestalk gene expression | decreased mound size | aberrant response to oxidative stress | decreased fruiting body size | increased mitochondrial fission | decreased cAMP level | abolished chemotaxis to cAMP
DBS0264268 adprt1B-adprt1Bwild type | decreased single-strand break repair | aberrant oscillatory cAMP signaling
DBS0350539 adprt2-adprt2decreased single-strand break repair | decreased double-strand break repair | decreased resistance to cisplatin
DBS0238203 adrm1-adrm1-1decreased catalytic activity | precocious gene expression | aberrant response to nutrient | precocious development
DBS0351596 agnA-agnAincreased pre-miRNA processing | aberrant production of siRNA involved in RNA interference | increased gene expression | abolished transitive RNA interference
DBS0351602 agnB-agnBdecreased gene expression
HW420 agtA-agtAdevelopment arrests at slug stage
DBS0235457 ahhA-ahhAaberrant late culminant morphology
DBS0252637 aip1-aip1decreased pinocytosis | delayed cytokinesis | decreased growth rate | decreased phagocytosis | increased actin filament polymerization | aberrant nucleus morphology | decreased cell motility
DBS0266759 alp-alpwild type
DBS0235513 alrA-alrAincreased mound size | decreased cell motility | decreased glucose level | decreased protein secretion
DBS0235473 alrA-/ [act15]: alrAalrAwild type
DBS0235474 alxA-alxAdevelopment arrests at loose mound stage | aberrant standing slug morphology | decreased growth rate
DBS0235475 alxA-alxAabolished sporulation | aberrant standing slug morphology | aberrant cellular process | decreased gene expression | development arrests at mound stage
DBS0235488 alxA-/ [act15]: FLAG: alxAalxAdelayed development
DBS0235476 alxA-/ [act15]: alxA(1-596): myc2alxAaberrant standing slug morphology
DBS0235477 alxA-/ [act15]: alxA(1-697): myc2alxAwild type
DBS0235478 alxA-/ [act15]: alxA(155-697): myc2alxAaberrant standing slug morphology
DBS0235479 alxA-/ [act15]: alxA(293-697): myc2alxAaberrant standing slug morphology
DBS0235480 alxA-/ [act15]: alxA(460-794): myc2alxAaberrant standing slug morphology
DBS0235481 alxA-/ [act15]: alxA(D310A/ N311A)alxAwild type
DBS0235482 alxA-/ [act15]: alxA(Q181E/ Q183)alxAwild type
DBS0235483 alxA-/ [act15]: alxA(S700A/ S704A/ S708A)alxAwild type
DBS0235484 alxA-/ [act15]: alxA(S700D/ S704D/ S708D)alxAwild type
DBS0235485 alxA-/ [act15]: alxA(Y315D)alxAwild type
DBS0235486 alxA-/ [act15]: alxA(Y315F)alxAwild type
DBS0235487 alxA-/ [act15]: alxA: myc2alxAwild type
DBS0235489 alyA-alyAincreased phagocytosis
AK1350 alyL-alyLdecreased response to Gram-negative bacterium
DG1114 amdA-amdAdecreased spore germination | aberrant sorus color | increased prestalk A cell differentiation
HM1158 amdA-amdAdecreased fruiting body size | decreased sporulation | increased cell differentiation
DBS0235490 amiB-amiBabolished aggregation
DBS0235491 amiB-amiBaberrant cell motility | increased gene expression | decreased gene expression | decreased oscillatory cAMP signaling | decreased cGMP-mediated signaling | abolished aggregation | decreased chemotaxis to cAMP
DBS0235493 ampA-ampAdelayed development of tipped mound | delayed prestalk gene expression | precocious prespore gene expression | increased cell-cell adhesion | increased cell-substrate adhesion | aberrant gene expression | delayed development | decreased prestalk cell differentiation
DBS0349962 ampA-ampAwild type | decreased actin filament polymerization | aberrant chemotaxis to folate | increased cell-substrate adhesion | decreased pseudopodium formation
DBS0235496 ampA-/ pspD: lacZampAaberrant prespore gene expression
DBS0349952 ampA/ [ampA]: ampA/ lmbd2B-ampA | lmbd2Baberrant chemotaxis
BS155 amtA-amtAdecreased slug migration | decreased mound size | decreased fruiting body size | increased growth rate | decreased ammonia level
DBS0267100 amtA-amtAincreased number of mounds | increased glucose level | decreased mound size | decreased ammonia level | decreased stalk length | aberrant sporulation | increased intracellular ammonia level
DBS0267101 amtA-/ [OE]: amtAamtAwild type
amtB-amtB
BS154 amtC-amtCabolished protein localization to nucleus | development arrests at slug stage | aberrant gene expression | decreased prestalk gene expression | aberrant fruiting body morphogenesis | decreased ammonia level | delayed culmination
DBS0235501 amtC-/ [act15]: cudAamtC | cudAdelayed culmination
DBS0235502 amtC-/ [ecmA]: cudAamtC | cudAdelayed culmination
DBS0235503 amtC-/ [pspA]: cudAamtC | cudAdevelopment arrests at slug stage
DBS0350432 aoxA-aoxAdecreased resistance to hydrogen peroxide | aberrant cellular process | aberrant sorocarp development
DBS0349869 ap1b1-ap1b1aberrant aggregation | aberrant cell separation during cytokinesis | aberrant contractile vacuole organization | decreased growth rate | aberrant hypotonic response | decreased protein stabilization
DBS0305197 ap2a1-ap2a1-1 | ap2a1-2aberrant cell separation during cytokinesis
DBS0350296 aph1-aph1aberrant culmination | abolished catalytic activity | decreased prespore cell differentiation
DBS0351357 aph1-aph1increased protein modification | decreased phagocytosis | decreased macropinocytosis | aberrant sorocarp development | decreased protein processing in phagocytic vesicle | delayed phagosome acidification
DBS0350805 apl-aplaberrant response to cisplatin
DBS0351160 aplD-aplDdecreased defense response to Gram-negative bacterium | decreased growth rate
DBS0351161 aplP-aplDdecreased growth rate
DBS0235505 apm1-apm1decreased spore germination | aberrant contractile vacuole organization | decreased growth rate | aberrant endosome morphology | aberrant hypotonic response | delayed development | decreased stalk width
DBS0235506 apm2-apm2aberrant cell separation during cytokinesis
DBS0305085 apm2-/ [dscB]: GFP: vamp7Aapm2 | vamp7Aincreased protein localization to plasma membrane
DBS0235507 apm3-apm3decreased pinocytosis | increased exocytosis | aberrant endosome morphology | decreased cellular localization | aberrant secretion | aberrant lysosome organization
DBS0305083 apm3-/ [dscB]: GFP: vamp7Aapm3 | vamp7Aincreased protein localization to plasma membrane
DBS0235508 apm4-apm4wild type
DBS0235509 aprA-aprAaberrant cellular homeostasis | increased mound size | decreased spore germination | increased cell death | aberrant cytokinesis | aberrant vegetative growth | aberrant fruiting body morphogenesis | increased growth rate | abolished chemorepellant activity | decreased sporulation
DBS0235510 aprA-/ [act15]: aprAaprAdecreased growth rate | aberrant fruiting body morphogenesis
DBS0350009 aprA-/ [act15]: bzpN: GFPaprA | bzpNabolished negative regulation of vegetative growth
DBS0238124 aqpA-aqpAdecreased spore germination | decreased sporulation
DBS0351484 aqpB-aqpBdecreased cell motility
DBS0351067 araA-araAdelayed aggregation | increased cell-substrate adhesion | decreased cell motility | increased protein kinase activation
DBS0350886 areA-areAincreased autophagy
DBS0350887 areB-areBincreased autophagy
DBS0235511 arkA-arkAincreased gene expression | aberrant fruiting body morphogenesis
DBS0350191 arpin-arpinincreased cell motility
DBS0350206 arpin-/ [act15]: GFP: arpinarpinwild type
DBS0350654 ase1A-ase1Aaberrant mitotic spindle organization | aberrant cytokinesis | aberrant microtubule cytoskeleton organization
DBS0350655 ase1B-ase1Baberrant cell morphology
DBS0235514 aslA-aslA-1 | aslA-2wild type
DBS0351219 ate1-ate1aberrant cell motility | decreased cell-substrate adhesion | decreased vegetative cell size | aberrant actin filament organization
DBS0236305 atg1-atg1aberrant macroautophagy | abolished autophagosome organization
DBS0236304 atg1-atg1aberrant macroautophagy | aberrant mitochondrion morphology | abolished autophagosome organization
DBS0350450 atg1-atg1aberrant autophagy | decreased defense response to Gram-negative bacterium | aberrant defense response to bacterium | aberrant vacuole organization
DBS0350839 atg1-atg1decreased catalytic activity | abolished protein localization to autophagosome
HR131 atg1-atg1abolished macroautophagy | increased number of autophagosomes | aberrant autophagy | decreased defense response to Gram-negative bacterium | aberrant cellular response to nitrogen starvation | decreased growth rate | abolished spore cell differentiation | aberrant vacuole organization | abolished stalk cell differentiation | abolished aggregation | increased defense response to fungus | decreased defense response to Gram-positive bacterium | aberrant protein localization
DBS0238085 atg1-/ [act15]: atg1atg1wild type
DBS0238092 atg1-/ [act15]: atg1(1-628)atg1aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238087 atg1-/ [act15]: atg1(K36A)atg1aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238093 atg1-/ [act15]: atg1(P138S)atg1abolished aggregation
DBS0350884 atg101-atg101increased number of tip-organizers | decreased autophagy
DBS0351232 atg12-atg12decreased pinocytosis | increased cell death | decreased spore germination | decreased catalytic activity | increased gene expression | increased number of mound tips | increased protein modification | decreased phagocytosis | aberrant phagosome maturation | aberrant fruiting body morphogenesis
DBS0351233 atg12-/ tipD-atg12 | tipDdecreased pinocytosis | increased cell death | decreased spore germination | increased gene expression | increased number of mound tips | increased protein modification | decreased phagocytosis | aberrant phagosome maturation | aberrant fruiting body morphogenesis
DBS0350883 atg13-atg13aberrant autophagy | abolished aggregation
DBS0350885 atg17-atg17wild type
HR75 atg5-atg5increased number of tip-organizers | aberrant macroautophagy | abolished sporulation | aberrant cellular response to nitrogen starvation | abolished aggregation | aberrant protein localization
DBS0351478 atg5-atg5abolished sporulation | decreased gene expression | delayed development
DBS0351582 atg5-atg5increased cell death | decreased catalytic activity | decreased growth rate | aberrant phagocytosis | increased protein modification | decreased macropinocytosis | aberrant fruiting body morphogenesis | increased growth rate
HR174 atg6-atg6Aincreased number of tip-organizers | aberrant macroautophagy | decreased defense response to Gram-negative bacterium | aberrant cellular response to nitrogen starvation | decreased spore cell differentiation | decreased defense response to fungus | decreased fruiting body size | decreased stalk length | decreased sporulation
HR79 atg7-atg7increased number of tip-organizers | aberrant macroautophagy | abolished sporulation | decreased defense response to Gram-negative bacterium | aberrant cellular response to nitrogen starvation | abolished spore cell differentiation | aberrant protein localization
DBS0351476 atg7-atg7aberrant sorus morphology | decreased spore germination | decreased gene expression | decreased prespore cell differentiation | delayed development
DBS0351477 atg7-/ [act15]: YFP: atg7(C563A)atg7aberrant sorus morphology | decreased spore germination | delayed development
DBS0351479 atg7-/ [act15]: pkaC: YFPatg7 | pkaCdecreased gene expression | decreased sporulation
HR141 atg8-atg8aincreased number of tip-organizers | aberrant macroautophagy | aberrant spore morphology | aberrant cellular response to nitrogen starvation | decreased spore cell differentiation | aberrant vacuole organization | decreased fruiting body size | decreased defense response to Gram-positive bacterium | decreased sporulation
DBS0351222 atg8a-atg8aincreased cell death | decreased catalytic activity | increased number of mound tips | decreased growth rate | decreased phagocytosis | increased protein modification | delayed development | decreased fruiting body size | aberrant lysosome organization
DBS0351223 atg8b-atg8bprecocious development | aberrant lysosome organization
DBS0305977 atg9-atg9increased stalk width | decreased pinocytosis | abolished sporulation | aberrant sorus morphology | aberrant autophagy | decreased protein localization to autophagosome | increased number of mound tips | decreased gene expression | decreased phagocytosis | decreased growth rate | abolished catalytic activity | aberrant slug development | aberrant slug migration | aberrant protein modification | aberrant phagosome maturation | decreased prespore cell differentiation | aberrant fruiting body morphogenesis | delayed development | abolished phototaxis
DBS0350535 atg9-/ [act15]: cdcD(R154C): RFPatg9 | cdcDdecreased growth rate | decreased phototaxis
DBS0351589 atg9-/ [act15]: cdcD(R154C/ E219K): RFPatg9 | cdcDwild type
DBS0350534 atg9-/ [act15]: cdcD: RFPatg9 | cdcDdecreased growth rate | aberrant fruiting body morphogenesis | abolished phototaxis
DBS0351480 atg9-/ [act15]: pkaC: YFPatg9 | pkaCabolished sporulation
DBS0351043 atp1-atp1decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis
DBS0351044 atp6-atp6decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis
HM1591 axeB-axeBaberrant macropinocytosis | increased macropinocytosis | increased phagocytosis
DBS0351503 bcas3-bcas3decreased number of autophagosomes | aberrant fruiting body morphogenesis | aberrant phototaxis | decreased sporulation
DBS0351039 bzpF-bzpFdecreased spore germination | decreased gene expression | aberrant fruiting body morphogenesis | aberrant sporulation | decreased sporulation
DBS0349965 bzpN-bzpNaberrant cytokinesis | abolished negative regulation of vegetative growth | increased growth rate
DBS0350419 bzpR-bzpRincreased stalk width | aberrant sorus morphology | decreased sporulation
DBS0351486 c2gapB-c2gapBincreased cell motility | increased activation of GTPase activity
DBS0351619 cadA-cadAaberrant vegetative growth
TL97 cadA-cadAincreased number of tip-organizers | decreased calcium-dependent cell-cell adhesion | decreased protein level | increased gene expression | abolished cell migration to prestalk region | increased chemotaxis to cAMP | aberrant cytokinesis | decreased sporulation | delayed culmination | increased prestalk cell differentiation
DBS0351372 cadA-cadAaberrant defense response to bacterium | decreased growth rate | aberrant response to oxidative stress
JB4 carA-carA-1 | carA-2abolished aggregation
JS14 carA-carA-1 | carA-2abolished protein tyrosine phosphorylation | abolished protein localization to nucleus | aberrant phagocytosis | increased cell-substrate adhesion | decreased oscillatory cAMP signaling | decreased cGMP-mediated signaling | aberrant regulation of GTPase activity | abolished aggregation | aberrant regulation of protein kinase activity | abolished chemotaxis to cAMP
DBS0351266 carA-/ [act15]: gpbA: YFPcarA-1 | carA-2 | gpbAabolished aggregation
DBS0350431 carA-/ [unk]: carA(261-359;S299A,S302G,S303G,S304G,S308A,S324G,S325A,S331A)(369-392;S383A,S385A): eYFPcarA-1 | carA-2aberrant adaptation of signaling pathway | aberrant protein localization to plasma membrane
DBS0235570 carB-carBdevelopment arrests at mound stage
DBS0350661 carB-carBdevelopment arrests at mound stage | abolished development of tipped mound | increased prespore gene expression | decreased prestalk gene expression
JB6 carC-carCwild type
DBS0235568 carD-carDdecreased migratory slug size | decreased slug migration | increased prespore gene expression | decreased prestalk gene expression | aberrant slug migration | aberrant fruiting body morphogenesis | decreased stalk length | decreased prestalk cell differentiation
DBS0235573 carmil-carmildecreased pinocytosis | decreased actin filament polymerization | decreased growth rate | decreased mound size
IR40 catA-catAabolished catalase activity
IR41 catA-catAabolished catalase activity
IR29 catA-catAdecreased resistance to hydrogen peroxide
DBS0235574 catB-catBdecreased spore resistance to hydrogen peroxide | aberrant gene expression | delayed development | delayed gene expression
DBS0350249 cbhA-cbhAdelayed development
DBS0350250 cbhA-/ [cbhA]: cbhAcbhAwild type
DBS0304455 cblA-cblA-1 | cblA-2aberrant slug development | abolished basal disc formation | aberrant signal transduction
DBS0351096 cbpG-cbpGdecreased cell-substrate adhesion | decreased vegetative cell size
DBS0235575 cbpJ-cbpJwild type
DBS0350238 ccdc53-ccdc53abolished exocytosis | decreased growth rate | abolished phagosome reneutralization | abolished actin filament polymerization
DBS0235661 cdk8-cdk8decreased gene expression | aberrant gene expression | abolished aggregation
DBS0350435 cdk8-cdk8decreased spore germination | decreased gene expression | aberrant gene expression | abolished aggregation
DBS0350436 cdk8-/ [act15]: myc: cdk8cdk8wild type
DBS0350437 cdk8-/ [act15]: myc: cdk8(D194A)cdk8decreased spore germination | abolished aggregation
DBS0235578 cdk8-/ [cdk8]: cdk8cdk8wild type
DBS0306226 cenB-cenBincreased number of centrosomes | aberrant cell separation during cytokinesis | aberrant nuclear envelope morphology | abolished protein localization to microtubule organizing center | aberrant nucleus morphology | aberrant cytokinesis | decreased microtubule nucleation | aberrant centrosome organization
DBS0306227 cenB-/ [act15]: RFP: cenBcenBwild type
DBS0349926 cepC-cepCaberrant mitotic spindle organization | decreased growth rate | aberrant Golgi localization | abolished vegetative growth | aberrant centrosome organization
DBS0350265 cepK-cepKdecreased protein level | decreased protein localization to nuclear envelope | aberrant chemotaxis to cAMP | decreased growth rate | decreased mound size | decreased vegetative cell size | decreased fruiting body size
DBS0302444 cfaD-cfaDaberrant cellular homeostasis | increased cell death | decreased spore germination | aberrant vegetative growth | aberrant cytokinesis | aberrant fruiting body morphogenesis | increased growth rate | decreased sporulation
DBS0350010 cfaD-/ [act15]: bzpN: GFPbzpN | cfaDabolished negative regulation of vegetative growth
DBS0302446 cfaD-/ [act15]: cfaDcfaDwild type
HO101 chcA-chcAdecreased pinocytosis | delayed cell separation during cytokinesis | aberrant cytokinesis | decreased growth rate
HO103 chcA-chcAabolished sporulation | abolished cytokinesis | abolished gene expression | delayed aggregation | abolished vegetative growth | aberrant fruiting body morphogenesis
DBS0350090 chcA-/ [act15]: GFP: ap2a1ap2a1-1 | ap2a1-2 | chcAincreased protein localization
DBS0235588 chcA-/ [act15]: GFP: mhcAchcA | mhcAdecreased positive regulation of GTPase activity
DBS0302455 chcA-/ [act15]: epnA: GFPchcA | epnAaberrant protein localization to clathrin-coated pit
DBS0350091 chcA-/ [act15]: gppA: GFPchcA | gppAaberrant protein localization to plasma membrane
DBS0235589 chcA-/ [cotB]: lacZchcAaberrant prestalk gene expression | aberrant prespore gene expression
DBS0235590 chcA-/ [ecmA]: lacZchcAaberrant prestalk gene expression | aberrant prespore gene expression
DBS0235591 chcA-/ [ecmB]: lacZchcAaberrant prestalk gene expression | aberrant prespore gene expression
DBS0235592 chcA-/ [pspA]: lacZchcAaberrant prestalk gene expression | aberrant prespore gene expression
DBS0350524 chdA-chdAaberrant culmination | aberrant gene expression | decreased chemotaxis to cAMP
DBS0350525 chdB-chdBaberrant gene expression | delayed development
DBS0350526 chdC-chdCdecreased growth rate | development arrests at mound stage | aberrant gene expression | aberrant chromatin assembly | decreased chemotaxis to cAMP
DBS0350528 chdC-/ [ecmA]: lacZchdCdecreased prestalk cell differentiation
DBS0350527 chdC-/ [pspA]: lacZchdCdecreased prespore cell differentiation
HM1522 chlA-chlAabolished DIF-1 biosynthesis | aberrant slug development | aberrant fruiting body morphogenesis
LAS1 chtB-chtBdecreased socially cooperative development | increased growth rate
CCR2 chtC-chtCdecreased socially cooperative development | decreased prestalk A cell differentiation
LAS5 chtC-REMIchtCdecreased socially cooperative development
DBS0235601 clc-clcabolished cytokinesis | decreased protein localization to plasma membrane | aberrant hypotonic response | abolished vegetative growth | aberrant fruiting body morphogenesis
DBS0235604 clc-/ [act15]: GFP-clc(146-194)clcabolished cytokinesis | wild type | aberrant fruiting body morphogenesis
DBS0235605 clc-/ [act15]: GFP-clc(85-124)clcabolished cytokinesis | wild type | aberrant fruiting body morphogenesis
DBS0235607 clc-/ [act15]GFP: clc(1-124)clcabolished cytokinesis | wild type | aberrant fruiting body morphogenesis
DBS0350408 cldA-cldAdecreased gene expression
AK1338 clkB-clkBdecreased response to Gram-negative bacterium
DBS0235608 clmA-clmAaberrant contractile vacuole morphology | aberrant hypotonic response
DBS0350473 cln3-cln3aberrant aggregation | increased protein secretion | aberrant cell separation during cytokinesis | decreased hypotonic response | aberrant cellular process | increased pinocytosis | delayed aggregation | aberrant cell adhesion | aberrant slug migration | aberrant hyperosmotic response | precocious development | increased growth rate | decreased chemotaxis to cAMP | decreased protein secretion
DBS0350474 cln3-/ [act15]: GFP: cln3cln3wild type
DBS0351175 cln5-cln5decreased cell-cell adhesion | aberrant lipid storage | decreased cell-substrate adhesion | decreased chemotaxis to cAMP
DBS0235609 cluA-cluAdecreased mitochondrial fusion | decreased mitochondrial fission | aberrant cytokinesis | aberrant intracellular distribution of mitochondria | aberrant mitochondrion organization
DBS0349875 cluA-/ [act15]: cluAcluAwild type
DBS0235612 cmfB-cmfBdecreased gene expression | abolished aggregation
DBS0235613 cnrB-cnrBwild type
DBS0350308 cnrF-cnrFaberrant contractile vacuole organization | abolished hypotonic response | decreased contractile vacuole size | aberrant regulation of GTPase activity
DBS0350311 cnrF-/ cnrF(E623Q/ D659Q)cnrFaberrant contractile vacuole organization | abolished hypotonic response | decreased contractile vacuole size | aberrant regulation of GTPase activity
DBS0350310 cnrF-/ cnrF(R270A)cnrFaberrant contractile vacuole organization | abolished hypotonic response | decreased contractile vacuole size | aberrant regulation of GTPase activity
DBS0302655 cnrN-cnrNincreased oscillatory cAMP signaling | increased number of mounds | decreased spore germination | increased actin filament polymerization | aberrant cytokinesis | aberrant stream morphology | increased growth rate | abolished positive regulation of chemorepellant activity | decreased sporulation
DBS0302656 cnrN-/ [act15]: cnrNcnrNwild type
HG1770 cnxA-cnxAdecreased calcium ion import | aberrant calcium-mediated signaling
DBS0235615 cofB-cofBwild type
DBS0235616 cofC-cofC-1wild type
DBS0350522 comA-comAaberrant defense response to bacterium | aberrant phagocytosis | aberrant hyperosmotic response
DG1016 comB-comBabolished culmination
DBS0235618 comC-comCaberrant aggregation | aberrant stream morphology
DBS0235619 comD-comDabolished culmination
DBS0235620 comE-comEaberrant fruiting body morphogenesis | aberrant sorus color
DBS0235621 comF-comF-1 | comF-2abolished aggregation
DBS0235622 comG-comGincreased number of tip-organizers | development arrests at mound stage
DBS0235623 comH-comHdevelopment arrests at mound stage
HG1570 corA-corAincreased myosin II assembly | aberrant cytokinesis | decreased growth rate | decreased cell motility | aberrant cell morphology
HG1571 corA-corAincreased myosin II assembly | aberrant cytokinesis | decreased growth rate | decreased cell motility | aberrant cell morphology
DBS0351402 corA-corAaberrant actin cytoskeleton organization | aberrant cytokinesis
HG1569 corA-corAdecreased defense response to Gram-negative bacterium | increased myosin II assembly | aberrant cytokinesis | decreased growth rate | decreased phagocytosis | increased actin filament polymerization | decreased cell motility | aberrant cell morphology | decreased defense response to Gram-positive bacterium
DBS0350370 corA-corAdecreased defense response to Gram-negative bacterium | decreased gene expression | aberrant chemotaxis to cAMP | aberrant response to cAMP | decreased phagocytosis | aberrant cellular response to extracellular stimulus | decreased establishment of cell polarity | abolished aggregation
DBS0351521 corA-/ [act15]: FLAG: corA(1-432)corAabolished aggregation
DBS0350345 corA-/ [act15]: GFP: mhkAcorA | mhkAwild type
DBS0350346 corA-/ [act15]: GFP: mhkBcorA | mhkBwild type
DBS0350344 corA-/ [act15]: GFP: mhkCcorA | mhkCdecreased catalytic activity | wild type
DBS0350343 corA-/ [act15]: GFP: pakA(797-1197)corA | pakAwild type
DBS0350371 corA-/ [act15]: corAcorAwild type
DBS0350341 corA-/ [act15]: corA(I118A/ S119A/ P121A): GFPcorAwild type | aberrant binding | increased myosin II assembly
DBS0305825 corB-corBincreased lateral pseudopodium formation | aberrant phagocytosis | decreased growth rate | increased cell-substrate adhesion
DBS0349942 cosA-cosAdecreased cell motility | decreased fruiting body size | decreased chemotaxis to cAMP | aberrant actin filament organization | increased pseudopodium formation
TL55 cotA-cotAdecreased spore germination | aberrant spore coat morphology | abolished cellulose binding
TL26 cotB-cotBdecreased spore germination | aberrant spore coat morphology | abolished cellulose binding
TL52 cotC-cotCaberrant spore coat morphology
DBS0351045 cox3-cox3decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant fruiting body morphogenesis | aberrant phototaxis
DBS0351538 cpnA-/ AX4cpnAincreased contractile vacuole size
DBS0238297 cpnA-/ NC4A2cpnAdelayed hypotonic response | increased migratory slug size | decreased post-lysosomal vacuole size | increased mound size | aberrant thermotaxis | increased contractile vacuole size | increased exocytosis | decreased growth rate | aberrant cytokinesis | aberrant stalk cell differentiation | development arrests at slug stage | decreased number of post-lysosomal vacuoles | aberrant fruiting body morphogenesis | delayed development | abolished phototaxis
DBS0238320 cpnA-/ [act15]: GFP: cpnAcpnAdelayed hypotonic response | decreased culmination | delayed development
DBS0350869 crlA-/ AX2crlAwild type
DBS0235627 crlA-/ KAX3crlAdelayed development of tipped mound | abolished polyketide metabolic process | increased mound size | decreased spore germination | decreased spore cell differentiation | decreased cell migration to prestalk region | increased growth rate
DBS0235628 crlA-/ [crlA]: crlAcrlAincreased mound size
DBS0235629 crlB-crlBwild type
DBS0235630 crlC-crlCwild type
HG1768 crtA-crtAdecreased calcium ion import | aberrant calcium-mediated signaling
DBS0235633 crtf-crtfabolished sporulation | decreased gene expression | abolished aggregation
DBS0351557 cryS-crySdecreased pinocytosis | decreased culmination | decreased phagocytosis | aberrant cytokinesis | decreased growth rate
AX2-T10 csaA-csaAdecreased cell-cell adhesion | decreased culmination | abolished protein localization to cell-cell contact zone | delayed aggregation | increased cell-substrate adhesion | decreased sporulation
WTC127 cshA-cshAdevelopment arrests at loose mound stage | decreased phagocytosis | decreased growth rate | delayed aggregation
DBS0235624 ctnA-ctnAincreased cGMP-mediated signaling | aberrant cellular metabolic process | increased glucose level | decreased protein level | increased mound size | decreased catalytic activity | increased guanylyl cyclase activity | decreased actin filament polymerization | decreased oscillatory cAMP signaling | increased cell-cell adhesion | increased protein level | increased cell motility | decreased myosin II assembly
DBS0235636 ctnB-ctnBincreased number of mounds | decreased gene expression | decreased fruiting body size
DBS0304927 ctnnA-ctnnAwild type
DG1071 ctr9-ctr9aberrant fruiting body morphogenesis
DG1058 ctrA-ctrAdecreased fruiting body size
DBS0350915 ctsD-ctsDaberrant protein modification
DBS0235598 ctxA-ctxAaberrant cytokinesis | decreased cell motility | aberrant cell morphology
HS1151 ctxA-ctxAaberrant cytokinesis | decreased growth rate | aberrant stream morphology | aberrant cellular response to stress
DBS0237568 ctxA-/ [RNAi]enlActxA | enlAwild type
DBS0349922 ctxA-/ [act15]: GFP-mhcActxAaberrant protein localization to basolateral plasma membrane | aberrant stalk morphogenesis | aberrant development of tipped mound
DBS0237536 ctxA-/ [act15]: enlA(92-497)ctxA | enlAwild type
DBS0235600 ctxB-ctxBaberrant cytokinesis | aberrant stream morphology | aberrant cell morphology
DBS0350404 ctxC-ctxCincreased pinocytosis | decreased oscillatory cAMP signaling | aberrant stream morphology | decreased chemotaxis to cAMP | increased growth rate | increased phagocytosis
DBS0235639 cudA-cudAabolished sporulation | decreased gene expression | development arrests at slug stage | decreased prespore gene expression | abolished stalk cell differentiation
DBS0238017 cudA-cudAabolished gene expression
DBS0235640 culA-culAincreased number of tip-organizers | development arrests at tipped mound stage
DBS0235641 culA-/ [cotC]: culAculAincreased sorus size | decreased stalk length | decreased sporulation
DBS0235642 culA-/ [ecmA]: culAculAincreased sorus size | decreased stalk length
DBS0235643 culA-/ [pkaC]pkaCculA | pkaCwild type
DBS0266745 culB-culBincreased number of mound tips | precocious prestalk gene expression | aberrant slug development | decreased fruiting body size | decreased sporulation
DBS0266761 culB-/ [act15]: pkaCculB | pkaCabolished sporulation | precocious prestalk gene expression | abolished aggregation | abolished prespore gene expression
DBS0235651 cybA-cybAabolished sporulation | aberrant sorocarp development
DBS0350641 cynA-cynAaberrant cell motility | decreased actin filament polymerization | aberrant chemotaxis to cAMP | delayed aggregation | aberrant cell morphology
DBS0351047 cytB-cytBdecreased defense response to Gram-negative bacterium | decreased gene expression | development arrests at mound stage | decreased growth rate | aberrant phototaxis
AK108 dagA-dagAabolished gene expression | decreased gene expression | abolished activation of adenylate cyclase activity | abolished aggregation | decreased chemotaxis to cAMP
BW4 dagA-dagAabolished positive regulation of chemorepellant activity
DBS0235652 dagA-/ [act15]: dagAdagAwild type
DBS0235560 dagA-/ acaA(L394S)acaA | dagAwild type
DBS0235653 darA-darAdecreased mound size | abolished aggregation
DBS0350531 dclre1-dclre1decreased resistance to bleomycin | decreased double-strand break repair via nonhomologous end joining | aberrant double-strand break repair via homologous recombination
DBS0236307 dcsA-dcsAabolished cellulose biosynthesis
DG1099 dcsA-dcsAabolished stalk development | abolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis | abolished stalk cell differentiation
DG1128 dcsA-dcsAabolished stalk development | abolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis
TL127 dcsA-dcsAabolished stalk development | abolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis | abolished stalk cell differentiation | aberrant stalk development
TL128 dcsA-/ [act15]: dcsAdcsAwild type
DBS0351195 dct-dctaberrant chemotaxis to cAMP | increased activation of GTPase activity
DBS0349967 dcx-/ lis1(D327H)dcx | lis1abolished aggregation
DBS0349804 detA-detAincreased mound size | decreased growth rate | delayed development
DBS0349813 detA-/ [cotB]: GFPdetAdecreased prespore cell differentiation
DBS0349811 detA-/ [ecm0]: lacZdetAaberrant prestalk O cell differentiation
DBS0349812 detA-/ [ecmA0]: GFPdetAincreased prestalk cell differentiation
DBS0349808 detA-/ [ecmA0]: lacZdetAincreased prestalk cell differentiation
DBS0349809 detA-/ [ecmA]: lacZdetAincreased prestalk A cell differentiation
DBS0349810 detA-/ [ecmB]: lacZdetAdelayed development
DBS0350392 dgat1-dgat1aberrant cellular metabolic process | abolished lipid droplet formation | increased sporulation
DBS0349911 dgcA-dgcAdecreased gene expression | development arrests at slug stage | abolished stalk cell differentiation
DBS0349917 dgcA-/ [act15]: dgcA(1-124): YFPdgcAdevelopment arrests at slug stage
DBS0349918 dgcA-/ [act15]: dgcA(1-273): YFPdgcAdevelopment arrests at slug stage
DBS0349914 dgcA-/ [act15]: dgcA(125-521): YFPdgcAwild type
DBS0349915 dgcA-/ [act15]: dgcA(274-521): YFPdgcAwild type
DBS0349916 dgcA-/ [act15]: dgcA(350-521): YFPdgcAdevelopment arrests at slug stage
DBS0349913 dgcA-/ [act15]: dgcA-Ppal: YFPdgcAwild type
DBS0349912 dgcA-/ [act15]: dgcA: YFPdgcAwild type
DBS0235695 dgkA-dgkAdecreased spore germination | increased myosin II assembly | aberrant sorocarp development | decreased chemotaxis rate
DBS0351179 dgkA-dgkAaberrant cellular metabolic process | increased resistance to valproic acid | aberrant response to lithium
AK299 dhkA-dhkAaberrant stalk morphogenesis | increased prestalk gene expression | aberrant gene expression | aberrant fruiting body morphogenesis | increased sporulation | abolished response to biotic stimulus | decreased sporulation
DBS0350665 dhkA-/ [act15]: dhkA(D2076N)dhkAdecreased sporulation
DBS0350664 dhkA-/ [act15]: dhkA(H1396Q)dhkAdecreased sporulation
DBS0350666 dhkA-/ [act15]: dhkA(H2396Q)/ [act15]: dhkA(D2076N)dhkAwild type
DBS0235703 dhkA-/ [pkaC]: pkaCdhkA | pkaCaberrant stalk morphogenesis
DBS0235704 dhkB-dhkBprecocious spore germination | decreased cAMP level | aberrant sorus color
TL135 dhkC-dhkCprecocious culmination | decreased spore germination | precocious aggregation | precocious development | precocious gene expression
DBS0350855 dhkC-dhkCaberrant chemotaxis to cAMP
DBS0350379 dhkD-dhkDabolished stream development | aberrant slug development | aberrant sorocarp development | precocious gene expression | aberrant late culminant morphology
DBS0350381 dhkD-/ [ecmAO]: lacZdhkDaberrant prestalk cell differentiation
DBS0350382 dhkD-/ [ecmB]: lacZdhkDaberrant prestalk cell differentiation
DBS0350383 dhkD-/ [pspA]: lacZdhkDaberrant prespore cell differentiation
LAS99 dhkE-dhkEdecreased socially cooperative development
DBS0351297 dhkI-dhkI-1 | dhkI-2aberrant chemotaxis to cAMP | delayed aggregation
DBS0235710 dhkK-dhkKaberrant slug migration | delayed culmination | delayed gene expression
DBS0235712 dhkK-/ [act15]: dhkK(D1125N)dhkKaberrant fruiting body morphogenesis
DBS0348046 dhkM-dhkMabolished autophagosome organization | aberrant autophagic cell death
DBS0348047 dhkM-dhkMabolished autophagosome organization | abolished actin filament depolymerization | abolished cellulose biosynthesis | abolished autophagic cell death
DBS0350173 dhkM-dhkMdecreased autophagic vacuole organization | delayed development
DBS0235895 dimA-dimAincreased standing slug length | increased migratory slug size | abolished prestalk cell differentiation | decreased standing slug width | aberrant fruiting body morphogenesis | increased prespore cell differentiation | decreased prestalk O cell differentiation
DBS0235901 dimB-dimBdecreased prestalk B cell differentiation | abolished response to DIF-1 | increased gene expression | aberrant prespore gene expression | aberrant chemotaxis to cAMP
DBS0235903 dimB-/ [act15]: dimA: GFPdimA | dimBabolished protein localization to nucleus
DBS0235904 dimB-/ [act15]: dimB: GFPdimBwild type
DBS0235902 dimB-/ [cotB]: lacZdimBincreased prespore cell differentiation
DBS0350573 dimB-/ [dimB]: dimB(S590A)dimBwild type
DBS0235906 dimB-/ [ecmAO]: lacZdimBdecreased prestalk O cell differentiation
DBS0349974 dimB-/ [ecmB]: lacZdimBabolished prestalk gene expression
DBS0235907 dimB-/ [ecmO]: lacZdimBaberrant prestalk cell differentiation
DBS0350495 dio3-dio3decreased cell-cell adhesion | aberrant aggregation | decreased gene expression | decreased growth rate | decreased prespore cell differentiation | decreased chemotaxis to folate | increased prestalk cell differentiation | decreased cAMP level | decreased phototaxis
DBS0350496 dio3-/ [act15]: GFP: dio3dio3wild type
DBS0304919 dlpA-dlpAaberrant cell separation during cytokinesis | aberrant cytokinesis | decreased growth rate | increased actin filament depolymerization | increased vegetative cell size | decreased protein localization | abolished protein localization to cleavage furrow | aberrant actin filament organization
DBS0304920 dlpB-dlpBaberrant cell separation during cytokinesis | aberrant cytokinesis | decreased growth rate | increased vegetative cell size | abolished protein localization to cleavage furrow
DBS0304921 dlpC-dlpCaberrant cytokinesis
DBS0235913 dmpA-dmpAaberrant stream morphology | aberrant fruiting body morphogenesis | delayed development | decreased stalk cell differentiation | decreased sporulation | aberrant sorus color
HM1030 dmtA-dmtAdelayed development of tipped mound | abolished DIF-1 biosynthesis | decreased outer basal disc size | wild type | abolished prestalk O cell differentiation | decreased standing slug width | decreased lower cup size | decreased prestalk gene expression | aberrant vacuole organization | aberrant fruiting body morphogenesis | delayed development | decreased prestalk O cell differentiation | decreased prestalk cell differentiation
DBS0350410 dmtA-/ [act15]: dmtAdmtAwild type
DBS0349975 dmtA-/ [dimB]: dimBdimB | dmtAdecreased prestalk B cell differentiation
DBS0235914 dnapkcs-dnapkcsdecreased resistance to bleomycin | decreased double-strand break repair via nonhomologous end joining
DBS0266875 dnapkcs-/ GFP: pcnadnapkcs | pcnaaberrant response to bleomycin
DBS0235915 dng1-dng1decreased growth rate | delayed aggregation
DBS0235917 dnmA-dnmAdecreased DNA methylation on cytosine
DBS0235916 dnmA-dnmAdecreased DNA methylation on cytosine | aberrant late culminant morphology | aberrant sorus color | decreased sporulation
DBS0350457 docA-docAdecreased chemotaxis to cAMP
DG2015 docA-docAdevelopment arrests at mound stage
LAS32 docA-docAdecreased socially cooperative development
DBS0350458 docD-docDdecreased cell motility | decreased chemotaxis to cAMP
DBS0235920 dokA-dokAaberrant hyperosmotic response | aberrant sorus color | decreased sporulation
DBS0349789 dotA-dotAaberrant response to UV | decreased growth rate | decreased spore size | delayed development | abolished histone H3-K79 methylation
HAD172 dpoA-dpoAincreased gene expression | aberrant sorocarp development
HAD200 dpoA-dpoAaberrant sorocarp development
HAD201 dpoA-dpoAaberrant sorocarp development
HAD202 dpoA-dpoAaberrant sorocarp development
HAD203 dpoA-dpoAaberrant sorocarp development
HM1467 drcA-drcAabolished catalytic activity
DBS0238474 drkC-drkCdecreased phagocytosis | decreased phagolysosome formation
DBS0238511 drkC-/ [act15]: drkC(1-497): YFPdrkCdecreased phagocytosis
DBS0238513 drkC-/ [act15]: drkC(K518R): YFPdrkCdecreased phagocytosis
DBS0238475 drkC-/ [act15]: drkC: YFPdrkCwild type
DBS0350174 drnB-drnBabolished pre-miRNA processing
DBS0350218 drnB-/ [act15]: pre-miRNAdrnBabolished pre-miRNA processing
DBS0350210 drnB-/ [act6]: lacZ/ [RNAi]lacZdrnBabolished production of siRNA involved in RNA interference | abolished transitive RNA interference
DBS0235924 dscA-dscA-1 | dscA-2aberrant cell morphology
DBS0350775 dscA-dcsAdecreased cell motility
DBS0302608 dsgg(1-571: 581-733)/ dsgg-dsggaberrant contractile vacuole organization | aberrant cellular localization
DBS0302597 dsgg-dsggaberrant contractile vacuole organization | aberrant hypotonic response
DBS0302603 dsgg-/ GFP: dsggdsggwild type
DBS0302602 dsgg-/ OE]: dsgg(Delta-Fbox)dsggwild type
DBS0302606 dsgg-/ [OE]: GFP: lvsDdsgg | lvsDwild type
DBS0302599 dsgg-/ [OE]: dsggdsggwild type
DBS0302601 dsgg-/ [OE]: dsgg(Q551A)dsggaberrant contractile vacuole organization
DBS0302600 dsgg-/ [OE]: dsggR515A)dsggaberrant contractile vacuole organization
DBS0302607 dsgg-/ [OE]: lvsAdsgg | lvsAaberrant contractile vacuole organization
DBS0302611 dsgg-/ [OE]: phgAdsgg | phgAaberrant contractile vacuole organization
DBS0302678 dsgg-/ [OE]: rab8Adsgg | rab8Aaberrant contractile vacuole organization
DBS0302604 dsgg-/ lvsA-dsgg | lvsAwild type
DBS0302605 dsgg-/ lvsD-dsgg | lvsDaberrant contractile vacuole organization
DBS0351070 dspA-dspAdelayed aggregation | increased cell-substrate adhesion | decreased cell motility | increased protein kinase activation
DBS0235925 dstA-dstAabolished gene expression | increased gene expression | aberrant prestalk gene expression | abolished cell migration to prestalk region | decreased gene expression | delayed aggregation | decreased prestalk gene expression | decreased cell motility | abolished stalk cell differentiation | aberrant fruiting body morphogenesis
DBS0235926 dstA-dstAaberrant prestalk gene expression | abolished cell migration to prestalk region | delayed aggregation | decreased cell motility | abolished stalk cell differentiation | aberrant fruiting body morphogenesis
DBS0238237 dstA-/ GFP: dstA(237-707): ORF+dstAabolished culmination | decreased stalk length
DBS0238236 dstA-/ GFP: dstA(237-707): ORF+/ [OE]dutA(751-1322)dstA | dutAdecreased stalk length
DBS0252824 dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 2C2C | dstAaberrant fruiting body morphogenesis
DBS0252823 dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 7E7E | dstA | hssBwild type
DBS0252826 dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0276165DDB_G0276165 | dstAaberrant fruiting body morphogenesis
DBS0252825 dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0282325DDB_G0282325 | dstAaberrant fruiting body morphogenesis
DBS0252816 dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssAdstA | hssAwild type
DBS0235928 dstA-/ [act15]: dstAdstAwild type
DBS0235929 dstA-/ [cprB]: dstAdstAwild type
DBS0235930 dstA-/ [ecmAO]: dstAdstAwild type
DBS0235931 dstB-dstBdecreased gene expression | increased gene expression | decreased growth rate
DBS0235933 dstB-/ [act15]: dstBdstBwild type
DBS0235934 dstB-/ [act15]: dstB(L1025R)dstBwild type
DBS0235935 dstB-/ [act15]: dstB(Y1143F)dstBwild type
DBS0238125 dstC-dstCabolished gene expression | aberrant response to cation stress | aberrant response to osmotic stress
DBS0350425 dstC-dstCaberrant protein phosphorylation
DBS0235937 dtfA-dtfAdelayed development of tipped mound | decreased cell-cell adhesion | aberrant cytokinesis | aberrant cell migration to prestalk region | aberrant fruiting body morphogenesis
DBS0350500 dupA-dupAincreased defense response to Gram-negative bacterium | abolished aggregation
DBS0350502 dupA-dupAincreased defense response to Gram-negative bacterium
DBS0238234 dutA-dutAwild type
DBS0235939 dwwA-dwwAaberrant cytokinesis | aberrant actin filament organization | aberrant cell morphology
DBS0350411 dydA-dydAincreased myosin II assembly | increased actin filament polymerization | increased protein localization to plasma membrane | decreased chemotaxis to cAMP
DBS0350414 dydA-/ dydA(1-278: 501-1211)dydAdecreased protein localization to cell cortex | increased myosin II assembly | increased actin filament polymerization | aberrant chemotaxis to cAMP
DBS0350415 dydA-/ dydA(1-586: 703-1211)dydAdecreased protein localization to cell cortex | decreased chemotaxis to cAMP
DBS0350060 dymA-dymAdecreased protein localization to cleavage furrow | aberrant cell separation during cytokinesis | decreased growth rate | increased vegetative cell size | aberrant actin filament organization
DBS0347874 dymA-dymAdecreased pinocytosis | aberrant cell separation during cytokinesis | aberrant mitochondrion morphology | decreased phagolysosome size | increased basal disc size | decreased growth rate | aberrant nucleus morphology | increased vegetative cell size | aberrant endosome morphology | aberrant phagosome maturation | delayed development | aberrant stalk development | aberrant fruiting body morphogenesis | decreased establishment of cell polarity | aberrant pseudopodium formation | abolished phagosome acidification | increased phagocytosis | aberrant intracellular distribution of mitochondria
DBS0349839 dymA-/ [dymA]: dymAdymAwild type
DBS0347875 dymB-dymBdecreased growth rate | aberrant hypotonic response | increased cell-cell adhesion | increased cell-substrate adhesion | decreased vegetative cell size | decreased catalase activity | aberrant actin filament organization | increased growth rate | increased phagocytosis
DBS0235940 eb1-eb1aberrant mitosis | aberrant cytokinesis | aberrant protein localization
HJW117 ecmA-ecmAincreased standing slug length | decreased standing slug width | decreased slime trail
HJW01 ecmB-ecmBwild type
HJW03 ecmB-ecmBwild type
DBS0235944 ecmF-ecmFwild type
DBS0350904 efbA-efbAaberrant cytokinesis | delayed development
DBS0235945 egeA-egeAdecreased activation of adenylate cyclase activity | decreased gene expression | abolished aggregation
DBS0350520 egeA-/ [unk]: YFP: carAcarA-1 | carA-2 | egeAdevelopment arrests at mound stage
DBS0350521 egeA-/ [unk]: pkaCegeA | pkaCdecreased gene expression | abolished aggregation
DBS0235946 egeB-egeBdevelopment arrests at mound stage
DBS0350802 ehd-ehdaberrant endosome morphology | aberrant phagosome maturation | decreased protein processing in phagocytic vesicle
DBS0350804 ehd-/ [act15]: dymA: GFPdymA | ehdaberrant phagosome maturation | decreased protein processing in phagocytic vesicle
DBS0351166 ei24-ei24aberrant aggregation | decreased spore germination | increased gene expression | decreased gene expression | decreased growth rate | aberrant cell cycle | delayed development | decreased chemotaxis to cAMP | decreased fruiting body size | decreased cAMP level | decreased sporulation
DBS0302590 elmoA-elmoAincreased protein localization to pseudopodium | decreased culmination | abolished establishment of cell polarity | increased actin filament polymerization | decreased cell motility | delayed development | increased pseudopodium formation | increased phagocytosis
DBS0302591 elmoA-/ [act15]: elmoA: GFPelmoAwild type
DBS0350065 elmoE-elmoEdecreased culmination | decreased actin filament polymerization at leading edge | decreased chemotaxis to cAMP
DBS0351604 elp3-elp3decreased protein level
DBS0302448 epnA-epnAaberrant spore morphology | decreased spore germination | abolished protein localization to cell cortex | aberrant cytokinesis | abolished protein localization to plasma membrane | aberrant actin cytoskeleton organization | abolished protein phosphorylation
DBS0302457 epnA-/ [act15]: GFP: epnA(253-677)epnAaberrant spore morphology | abolished protein localization to plasma membrane | abolished protein localization to clathrin-coated pit
DBS0302456 epnA-/ [act15]: epnA(1-133): GFPepnAaberrant localization to coated pits
DBS0302474 epnA-/ [act15]: epnA(R65A/ K78A): GFPepnAaberrant spore morphology | abolished protein localization to plasma membrane | abolished phosphatidylinositol-4,5-bisphosphate binding | abolished protein localization to clathrin-coated pit | abolished protein phosphorylation
DBS0302475 epnA-/ [act15]: epnA(T107A): GFPepnAaberrant spore morphology | abolished protein localization to plasma membrane
DBS0302454 epnA-/ [act15]: epnA: GFPepnAwild type
DBS0235947 eppA-eppAdecreased growth rate | delayed development | decreased chemotaxis to folate | decreased chemotaxis to cAMP | decreased cAMP level
DBS0235948 eppA-/ [act6]: myc: eppAeppAwild type
DBS0350028 erkA-erkAdecreased mound size | decreased chemotaxis to cAMP
DBS0350622 erkA-erkAaberrant development of tipped mound | aberrant stream morphology | abolished protein kinase activation | aberrant cellular response to extracellular stimulus | abolished positive regulation of chemorepellant activity
DBS0350623 erkA-erkAdecreased mound size | precocious development
DBS0350681 erkA-/ [act15]: gpaEerkA | gpaEwild type
DBS0350029 erkA-/ [act15]: mekA: FLAGerkA | mekAincreased protein localization to cell cortex
DBS0351296 erkB-erkBabolished chemotaxis to folate | increased actin filament polymerization | abolished protein phosphorylation
HS174 erkB-erkBdecreased catalytic activity | aberrant phagocytosis | decreased cell motility | decreased prespore gene expression | decreased prestalk gene expression | aberrant sorocarp development | decreased chemotaxis to folate | abolished aggregation | decreased chemotaxis to cAMP | aberrant cell morphology | decreased sporulation
AK240 erkB-erkBabolished aggregation | decreased sporulation
DBS0350606 erkB-erkBdecreased prespore cell differentiation
DBS0350683 erkB-/ [ecmA]: lacZerkBaberrant cell migration to prestalk region
DBS0350682 erkB-/ [unk]: erkB(P140S)erkBabolished sporulation
DBS0350530 exo1-exo1decreased resistance to bleomycin | decreased double-strand break repair via homologous recombination
DBS0304864 expl7-expl7wild type
DBS0235951 fadA-fadAincreased cellular thermotolerance
DBS0235952 fadB-fadBwild type
DBS0350240 fam21-fam21abolished exocytosis | aberrant vegetative growth | decreased protein localization to post-lysosomal vacuole | decreased protein processing in phagocytic vesicle | aberrant autophagic cell death | aberrant phagosome maturation | aberrant lysosome organization
DBS0236034 fam45-fam45wild type
DBS0236040 fam91-fam91wild type
DBS0350717 far1-far1aberrant binding | decreased actin filament polymerization | aberrant defense response to bacterium | aberrant macropinocytosis | decreased growth rate | aberrant phagocytosis | aberrant chemotaxis | decreased engulfment during phagocytosis | decreased chemotaxis to folate | decreased protein kinase activation | decreased folic acid binding | aberrant signal transduction
DBS0351093 far1-far1abolished chemotaxis to folate
DBS0351545 fatA-fatAaberrant lipid storage | decreased phagocytosis
DBS0235953 fbxA-fbxAdecreased sporulation
HR6 fbxA-fbxAdecreased socially cooperative development
DBS0235954 fbxA-/ [ecmA]: GFP(S65T)fbxAincreased prespore cell differentiation
DBS0235956 fbxA1-fbxAdevelopment arrests at slug stage | aberrant fruiting body morphogenesis | increased slug migration | delayed culmination
DBS0235957 fbxA2-fbxAdevelopment arrests at slug stage | aberrant fruiting body morphogenesis | increased slug migration | delayed culmination
DBS0235958 fbxA3-fbxAdevelopment arrests at slug stage | aberrant fruiting body morphogenesis | increased slug migration | delayed culmination
DG1148 fcpA-fcpAaberrant fruiting body morphogenesis
DBS0235960 fcsA-fcsAdecreased fatty acid level | decreased lipid droplet formation | increased sporulation
DBS0350128 fcsB-fcsBdecreased catalytic activity | decreased phagocytosis
DBS0350336 febA-febAwild type
DBS0350953 fhbA-fhbAincreased vegetative cell size | aberrant cellular response to stress
DBS0350954 fhbB-fhbBincreased vegetative cell size | aberrant cellular response to stress
DBS0235961 fimA-fimAdecreased vegetative cell size
HM1253 fncD2-fncD2decreased resistance to cisplatin
HM1416 fncE-fncEdecreased resistance to cisplatin
HM1356 fncI-fncIdecreased resistance to cisplatin
HM1302 fncL-fncLdecreased resistance to cisplatin
HM1407 fncM-fncMdecreased resistance to cisplatin
DBS0235966 forA-forAwild type
DBS0350667 forA-forAaberrant cellular response to fluid shear stress | decreased cell motility | increased cell motility
DBS0350669 forA-/ [act15]: GFP: mhcAforA | mhcAaberrant bleb assembly
DBS0235968 forB-forBwild type
DBS0235969 forC-forCaberrant culmination | aberrant fruiting body morphogenesis | development arrests at tipped mound stage
DBS0350280 forC-forCdelayed aggregation | aberrant sorocarp development | decreased chemotaxis to cAMP | decreased sporulation | abolished slug development | delayed gene expression
DBS0304905 forC-/ [act15]: GFP: forCforCwild type
DBS0350287 forF-forFdecreased fruiting body size | aberrant phototaxis | increased chemotaxis rate
DBS0350835 forG-forGdecreased growth rate | decreased phagocytosis | aberrant actin cytoskeleton organization | decreased macropinocytosis | aberrant actin filament organization
DBS0235970 forH-forHdecreased cell-substrate adhesion | decreased chemotaxis rate | increased cell motility | aberrant pseudopodium formation | aberrant cell morphology | decreased filopodium formation
DBS0235971 forH-/ [act15]: GFP: forHforHincreased filopodium formation | decreased cell motility | increased cell-substrate adhesion
HW435 fpaB-/ AX2fpaB-1 | fpaB-2decreased response to hypoxia | increased culmination | increased stalk length
DBS0302506 frmA-frmAdelayed aggregation | decreased cell motility | decreased mound size | increased cell-substrate adhesion | aberrant cell morphology
DBS0304440 frmA-/ [unk]: GFPfrmAdecreased gene expression | aberrant sorocarp development | increased cell-cell adhesion | delayed development | abolished phototaxis
DBS0302507 frmA-/ [unk]: frmA-HAfrmAwild type
DBS0350983 frmB-frmBaberrant aggregation | increased mound size | decreased cell-substrate adhesion | increased fruiting body size
DBS0350232 fscE-fscEaberrant positive regulation of chemorepellant activity | decreased growth rate | aberrant cytokinesis
DBS0350228 fslA-fslAaberrant cytokinesis
DBS0350230 fslB-fslBaberrant positive regulation of chemorepellant activity | decreased catalytic activity | aberrant cytokinesis
DBS0350229 fslK-fslKdecreased catalytic activity | aberrant vegetative growth | aberrant cytokinesis
DBS0350252 fspA-fspAdecreased gene expression | aberrant chemotaxis to folate | aberrant vegetative growth
DBS0350253 fspA-/ [unk]: fspA: FLAGfspAwild type
DBS0235976 fszA- fszAdecreased number of mitochondria | aberrant mitochondrion morphology
DBS0235980 fszB- fszBaberrant mitochondrion morphology | decreased number of mitochondria | decreased growth rate
DG1066 fut1-fut1aberrant fruiting body morphogenesis
DBS0305025 gabT-gabTprecocious development | decreased sporulation
DBS0305026 gabT-[pkaC]: pkaCgabT | pkaCaberrant protein secretion
DBS0351298 gacG-gacGincreased chemotaxis to folate | increased actin filament polymerization at leading edge
DBS0351318 gacG-gacGaberrant macropinocytosis | abolished vegetative growth
DBS0351299 gacH-gacHaberrant chemotaxis to cAMP
DG1094 gacT-gacTaberrant fruiting body morphogenesis
DBS0235989 gadA-gadAdecreased spore cell differentiation | decreased sporulation
DBS0350071 gadA-gadAdecreased spore germination
DBS0350072 gadB-gadBdelayed aggregation
DBS0350963 gapA-gapAaberrant cell separation during cytokinesis
DBS0349924 gapA-gapAdecreased actin filament bundle assembly
DBS0350399 gapA-gapAdecreased protein localization to cleavage furrow | increased myosin II assembly | increased lateral pseudopodium formation | aberrant mitotic spindle organization | increased actin filament polymerization | decreased chemotaxis to cAMP | aberrant cellular response to stress
TL198 gbfA-gbfAabolished gene expression | development arrests at mound stage
DBS0302689 gbfA-gbfAaberrant oscillatory cAMP signaling
DBS0305094 gbfA-gbfAabolished autophagosome organization | abolished autophagic cell death
DBS0235994 gbpC-gbpCdecreased protein kinase activation | decreased fruiting body size
DBS0235995 gbpC-gbpCaberrant chemotaxis to cAMP | aberrant myosin II filament organization | decreased chemotaxis rate | aberrant cyclic nucleotide binding | aberrant cell morphology | decreased establishment of cell polarity | decreased fruiting body size
DBS0302680 gbpC-gbpCabolished protein localization to nucleus | decreased mound size | abolished protein phosphorylation
DBS0350881 gbpC-gbpCaberrant cyclic nucleotide binding
DBS0304912 gbpC-/ [act15]: gbpCgbpCwild type
DBS0304917 gbpC-/ [act15]: gbpC(1-1698: 2005-2631)gbpCdecreased chemotaxis to cAMP
DBS0349868 gbpC-/ [act15]: gbpC(1-2331: 2470-2631): GFPgbpCaberrant stream morphology | decreased chemotaxis to cAMP
DBS0304918 gbpC-/ [act15]: gbpC(311-2631)gbpCdecreased chemotaxis to cAMP
DBS0304916 gbpC-/ [act15]: gbpC(F1892A)gbpCdecreased chemotaxis to cAMP
DBS0304915 gbpC-/ [act15]: gbpC(F2082A/ E2084A/ F2564A/ E2566A)gbpCdecreased chemotaxis to cAMP
DBS0304913 gbpC-/ [act15]: gbpC(K342N)gbpCdecreased chemotaxis to cAMP
DBS0304914 gbpC-/ [act15]: gbpC(K905W)gbpCdecreased chemotaxis to cAMP
DBS0235997 gbpD-gbpDincreased establishment of cell polarity | decreased cell-substrate adhesion | decreased lateral pseudopodium formation | increased chemotaxis rate
DBS0235998 gbpD-/ [act15]: gbpDgbpDincreased lateral pseudopodium formation | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant actin filament organization | abolished aggregation
DG1120 gbqA-gbqAaberrant fruiting body morphogenesis
DBS0350119 gcA-gcAdecreased guanylyl cyclase activity
DBS0236002 gcsA-gcsAabolished sporulation | aberrant cellular metabolic process | decreased gene expression | increased gene expression | development arrests at mound stage | abolished vegetative growth | mitotic G1 phase arrest | abolished aggregation | abolished prespore gene expression
DBS0350387 gcsA-/ [act15]: carAcarA-1 | carA-2 | gcsAabolished aggregation
DBS0236003 gcsA-/ [act15]: gcsAgcsAdecreased spore germination | development arrests at mound stage
DBS0350388 gcsA-/ [act15]: yakAgcsA | yakAwild type
DBS0236004 gdt1-gdt1increased gene expression | decreased growth rate | precocious aggregation
DBS0237190 gdt1-/ [act15]: pkaR(G135E/ G261A)gdt1 | pkaRincreased gene expression | abolished aggregation
DBS0236006 gdt2-gdt2increased gene expression | precocious aggregation
RI19 gefA-gefAdecreased actin filament polymerization | decreased gene expression | decreased activation of GTPase activity | abolished activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased chemotaxis rate | abolished aggregation | increased protein kinase activation
JB10 gefA-gefAabolished aggregation
DBS0350821 gefA-gefAdecreased actin filament polymerization | decreased activation of GTPase activity | aberrant chemotaxis to cAMP | decreased protein kinase activation | abolished aggregation
DBS0350449 gefA-/ [dscB]: rasG(S17N)gefA | rasGdecreased actin filament polymerization | decreased activation of GTPase activity | aberrant chemotaxis to cAMP | decreased protein kinase activation
DBS0351451 gefB-/ AX2gefBwild type
DBS0236009 gefB-/ AX3gefBabolished pinocytosis | delayed aggregation | increased actin filament polymerization | decreased phagocytosis | decreased growth rate | decreased mound size | abolished vegetative growth | aberrant fruiting body morphogenesis | aberrant cell morphology | increased bleb assembly | aberrant cytoskeleton organization
DBS0236868 gefC-gefCwild type
DBS0236869 (DBS0235543) gefD-gefDwild type | aberrant activation of GTPase activity
DBS0236870 gefE-gefEaberrant thermotaxis | aberrant activation of GTPase activity | aberrant phototaxis
DBS0350569 gefE-gefEdecreased activation of GTPase activity | increased gene expression | decreased response to DIF-1 | increased prespore cell differentiation
DBS0350822 gefH-gefHdecreased actin filament polymerization | decreased activation of GTPase activity | aberrant chemotaxis to cAMP | delayed development | decreased protein kinase activation
DBS0236012 gefK-gefKwild type
DBS0236871 gefL-gefLaberrant thermotaxis | aberrant phototaxis
HSB61 gefM-gefMincreased cGMP-mediated signaling | decreased lateral pseudopodium retraction | aberrant activation of adenylate cyclase activity | development arrests at mound stage | decreased chemotaxis rate
DBS0304968 gefQ-gefQdecreased positive regulation of GTPase activity | increased number of mound tips | increased myosin II assembly | increased lateral pseudopodium formation | abolished cell migration to prestalk region | abolished guanyl-nucleotide exchange factor activity | decreased growth rate | decreased fruiting body size | abolished phototaxis
DBS0304985 gefQ-/ [act15]: GFP: gefQ(172-654)gefQabolished guanyl-nucleotide exchange factor activity | decreased phototaxis
DBS0304986 gefQ-/ [act15]: GFP: gefQ(910-1298)gefQdecreased phototaxis
DBS0236014 gefR-gefRwild type | decreased activation of GTPase activity
DBS0349892 gefS-gefSwild type
DBS0349904 gemA-gemAdecreased ATP level | decreased growth rate
DBS0350811 gflB-gflBdecreased culmination | decreased protein localization to cell cortex | aberrant G protein-coupled receptor signaling | delayed aggregation | decreased mound size | decreased chemotaxis to cAMP | aberrant protein localization to plasma membrane | increased actin filament polymerization at leading edge | decreased myosin II assembly
HA201 gflB-gflBdecreased phagocytosis | aberrant mitotic actomyosin contractile ring contraction | increased actin filament polymerization | decreased macropinocytosis | increased substrate adhesion-dependent cell spreading
DBS0350814 gflB-/ [act15]: GFP: gflB(380-1601,T1180E)gflBdecreased chemotaxis to cAMP
DG1109 ggtA-ggtAaberrant fruiting body morphogenesis
DBS0351210 gip1-gip1decreased protein localization to plasma membrane | aberrant chemotaxis to cAMP
DBS0266723 glcS-/ DH1glcSaberrant stalk morphogenesis | decreased glycogen level | decreased spore size | decreased fruiting body size
DBS0266765 glcS-/ HMXglcSabolished cellulose biosynthesis | decreased autophagic vacuole organization | aberrant cell morphology
DBS0350514 glk-glkdecreased defense response to Gram-negative bacterium
DBS0351101 glkA-glkAaberrant aggregation | decreased protein localization to cell cortex | decreased protein level | decreased chemotaxis to cAMP | decreased myosin II assembly | increased activation of GTPase activity | increased protein kinase activation
DBS0236078 glpD-glpDaberrant glycogen metabolism | aberrant regulation of catalytic activity
DBS0236079 gmsA-gmsAdecreased sexual fusion
DBS0236080 gmsA-gmsAdecreased sexual fusion
DBS0238384 gnt14-gnt14wild type
DBS0238382 gnt15-gnt15decreased gene expression | decreased growth rate | increased calcium-independent cell-cell adhesion | abolished aggregation | abolished culmination
DBS0238383 gnt15-gnt15decreased gene expression | decreased growth rate | increased calcium-independent cell-cell adhesion | abolished aggregation | abolished culmination
DBS0238390 gnt15-/ [act15]: FLAG: gnt15gnt15wild type
DBS0238391 gnt15-/ [act15]: FLAG: gnt15gnt15wild type
DBS0236081 gnt2-gnt2abolished catalytic activity | abolished protein modification
DBS0236082 gol-golincreased resistance to cisplatin
DBS0235414 gp130-gp130decreased response to Gram-positive bacterium | decreased cell-substrate adhesion | delayed development | increased growth rate
DBS0236087 gpaA-gpaAaberrant aggregation | increased stalk length | aberrant response to cAMP | decreased stalk width
JH131 gpaA-gpaAaberrant cellular homeostasis | wild type | increased growth rate
DBS0236091 gpaA-/ [ecmB]: lacZgpaAdecreased prestalk gene expression
DBS0236092 gpaA-/ [gpaA]: gpaA(G45V)gpaAdelayed development
DBS0236093 gpaA-/ [gpaA]: gpaA(Q206L)gpaAincreased basal disc size
DBS0236575 gpaB-gpaBdecreased response to cAMP | abolished activation of GTPase activity | aberrant phagocytosis | decreased cGMP-mediated signaling | decreased protein kinase activation | abolished aggregation | abolished chemotaxis to cAMP
JH104 gpaB-gpaBdecreased gene expression | decreased activation of GTPase activity | abolished activation of adenylate cyclase activity | abolished aggregation | abolished chemotaxis to cAMP
JM1 gpaB-/ [OE]: carAcarA-1 | carA-2 | gpaBaberrant calcium-mediated signaling
DBS0236096 gpaB-/ [act15]: gpaBgpaBabolished aggregation
DBS0266942 gpaB-/ [act15]: gpaBgpaBdelayed aggregation
DBS0266939 gpaB-/ [act15]: gpaB(1-345): gpaD(337-345)gpaB | gpaDabolished aggregation
DBS0351103 gpaB-/ [act15]: gpaB(C4A)gpaBabolished protein localization to plasma membrane | decreased cGMP-mediated signaling | abolished aggregation
DBS0237137 gpaB-/ [act15]: gpaB(D154V)gpaBaberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate
DBS0237138 gpaB-/ [act15]: gpaB(E190G)gpaBaberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling
DBS0351105 gpaB-/ [act15]: gpaB(G207A)gpaBabolished protein localization to plasma membrane
DBS0351104 gpaB-/ [act15]: gpaB(G2A)gpaBabolished protein localization to plasma membrane
DBS0237139 gpaB-/ [act15]: gpaB(I104S)gpaBaberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate
DBS0237140 gpaB-/ [act15]: gpaB(L110S)gpaBaberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate
DBS0237141 gpaB-/ [act15]: gpaB(L76P)gpaBabolished aggregation
DBS0237142 gpaB-/ [act15]: gpaB(N74D)gpaBdecreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate | abolished aggregation
DBS0237143 gpaB-/ [act15]: gpaB(R64G)gpaBdecreased chemotaxis rate | abolished aggregation
DBS0237144 gpaB-/ [act15]: gpaB(S155P)gpaBdecreased chemotaxis rate | abolished aggregation
DBS0351217 gpaB-/ [act15]: gpaIgpaB | gpaIwild type
DBS0351267 gpaB-/ [act15]: gpbA: YFPgpaB | gpbAabolished aggregation
DBS0351214 gpaB-/ [act15]: rasG(S17N)gpaB | rasGabolished activation of GTPase activity
DBS0236097 gpaB-/ [gpaA]: gpaBgpaBabolished aggregation
DBS0236099 gpaB-/ [gpaB]: gpaBgpaBwild type
DBS0236098 gpaB-/ [gpaB]: gpaB(Q208L)gpaBaberrant protein localization to plasma membrane
DBS0235986 gpaC-gpaCaberrant activation of adenylate cyclase activity | decreased gene expression | increased protein kinase activity | abolished aggregation
JH417 gpaD-gpaDdecreased gene expression | aberrant macropinocytosis | decreased spore cell differentiation | aberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased protein kinase activation | abolished protein phosphorylation | decreased cGMP biosynthesis | decreased sporulation
DBS0266944 gpaD-/ [act15]: gpaBgpaB | gpaDaberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased cGMP biosynthesis
DBS0266946 gpaD-/ [act15]: gpaB(1-345): gpaD(337-345)gpaB | gpaDaberrant fruiting body morphogenesis | decreased cGMP biosynthesis
DBS0266943 gpaD-/ [act15]: gpaDgpaDwild type
DBS0350608 gpaD-/ [act15]: gpaD(Q200L)gpaDdevelopment arrests at loose mound stage | decreased chemotaxis to folate | decreased protein kinase activation
DBS0350607 gpaD-/ [act15]: gpaD(R107E,R108E)gpaDdevelopment arrests at slug stage | aberrant slug development
DBS0266945 gpaD-/ [act15]: gpaEgpaD | gpaEaberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased cGMP biosynthesis
DBS0266947 gpaD-/ [act15]: gpaE(1-339): gpaD(337-345)gpaD | gpaEaberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased cGMP biosynthesis
DBS0351269 gpaD-/ [act6]: AEQgpaDaberrant calcium-mediated signaling
JH257 gpaE-gpaEdelayed development of tipped mound | increased chemotaxis to folate | delayed prestalk gene expression | increased vegetative cell size | delayed prespore gene expression | decreased cell migration to prestalk region
DBS0266941 gpaE-/ [act15]: gpaEgpaEprecocious development of tipped mound
DBS0266948 gpaE-/ [act15]: gpaE(1-339): gpaD(337-345)gpaD | gpaEprecocious development of tipped mound
DBS0350678 gpaE-/ [act15]: gpaE(K10E/ K11E)gpaEdelayed development of tipped mound | delayed gene expression
LW1 gpaG-gpaGwild type | decreased spore cell differentiation | aberrant GABA signaling pathway
DBS0236107 gpaH-gpaHwild type | increased cell death | decreased spore germination | abolished negative chemotaxis | increased growth rate | abolished positive regulation of chemorepellant activity | decreased sporulation
DBS0236108 gpaH-gpaHwild type
DBS0350972 gpaH-/ AX2gpaHincreased growth rate
DBS0350975 gpaH-/ [ecmO]: lacZgpaHaberrant cell differentiation
DBS0236109 gpaI-gpaIincreased number of mounds | aberrant cellular homeostasis | increased establishment of cell polarity | increased cell death | aberrant activation of adenylate cyclase activity | increased chemotaxis to cAMP | precocious aggregation | increased actin filament polymerization | aberrant adaptation of signaling pathway | decreased mound size | decreased oscillatory cAMP signaling | decreased lateral pseudopodium formation | decreased fruiting body size | increased growth rate | aberrant protein localization to plasma membrane | increased cGMP biosynthesis
DBS0351544 gpat-gpataberrant lipid storage | decreased lipid droplet formation | increased sporulation | increased phagocytosis
LW5 gpbA-gpbAaberrant taxis | increased resistance to N-Phenylthiourea | abolished aggregation
LW6 gpbA-gpbAdecreased protein localization to plasma membrane | aberrant cellular homeostasis | aberrant extracellular cAMP signaling pathway | decreased positive regulation of GTPase activity | increased cell death | abolished chemotaxis to folate | aberrant phagocytosis | aberrant chemotaxis | abolished activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased engulfment during phagocytosis | aberrant sorocarp development | decreased chemotaxis to folate | decreased protein kinase activation | decreased chemotaxis to cAMP | abolished actin filament polymerization | increased growth rate | aberrant protein localization | aberrant signal transduction
DBS0351277 gpbA-gpbAaberrant cytokinesis
DBS0350470 gpbA-/ [act15]: GFP: capcap | gpbAdecreased phagocytosis
LW14 gpbA-/ [act15]: carAcarA-1 | carA-2 | gpbAaberrant calcium-mediated signaling | decreased protein kinase activation | abolished aggregation
LW17 gpbA-/ [act15]: carCcarC | gpbAabolished aggregation
DBS0351260 gpbA-/ [act15]: gpbA(A99T/ Y271H/ C335M)gpbAabolished activation of adenylate cyclase activity | aberrant fruiting body morphogenesis
DBS0351261 gpbA-/ [act15]: gpbA(M30V/ K85R/ S104P/ Q163H)gpbAdevelopment arrests at mound stage | abolished activation of adenylate cyclase activity | decreased chemotaxis to cAMP
DBS0351263 gpbA-/ [act15]: gpbA(M48T/ I52T/ E310G)gpbAwild type | decreased activation of adenylate cyclase activity | decreased gene expression | aberrant slug development
DBS0351259 gpbA-/ [act15]: gpbA(N147D/ H149R/ N237S)gpbAdevelopment arrests at mound stage | abolished activation of adenylate cyclase activity | abolished chemotaxis to cAMP
DBS0351264 gpbA-/ [act15]: gpbA(R13G/ N74S/ S79P/ H149R/ V178A/ V194R/ F293L)gpbAdecreased activation of adenylate cyclase activity | decreased gene expression | development arrests at tipped mound stage
DBS0351262 gpbA-/ [act15]: gpbA(S196G/ V199D/ C211R)gpbAdecreased activation of adenylate cyclase activity | aberrant fruiting body morphogenesis
DBS0351258 gpbA-/ [act15]: gpbA(V88A/ F229S/ D235V)gpbAabolished activation of adenylate cyclase activity | aberrant fruiting body morphogenesis | decreased chemotaxis to cAMP
DBS0351268 gpbA-/ [act6]: AEQgpbAaberrant calcium-mediated signaling
HO547 gpbA-/ [act6]: FRB: [act15]: RFP: gpbA/ [act15]: cnxA: CFP: FKBP/ [act15]: limE(1-145): GFPgpbAaberrant cortical actin cytoskeleton organization
HO543 gpbA-/ [act6]: FRB: [act15]: RFP: gpbA/ [act15]: cnxA: YFP: FKBPgpbAabolished chemotaxis to folate
DBS0351198 gpbA-/ [act6]: yakAgpbA | yakAabolished vegetative growth
DBS0350832 gpbA-/ [unk]: gpbA(Q208L)gpbAaberrant adaptation of signaling pathway
DBS0351278 gpbA-/ mhcA-gpbA | mhcAaberrant cytokinesis
AK1353 gpi-gpidecreased response to Gram-positive bacterium
DBS0350477 gpr89-gpr89aberrant spore morphology | aberrant mitochondrion morphology | abolished cell migration to prestalk region | decreased gene expression | aberrant slug development | abolished vegetative growth | decreased cell motility | decreased fruiting body size | precocious gene expression | decreased phototaxis | delayed gene expression
DBS0350479 gpr89-/ [act15]: gpr89: GFPgpr89wild type
DBS0304814 grlA-grlAdelayed prestalk gene expression | decreased prestalk gene expression | decreased spore cell differentiation | decreased sporulation | delayed culmination
DBS0304815 grlA-/ [act15]: grlA: GFPgrlAaberrant development of tipped mound
DBS0350074 grlB-grlBdecreased small molecule binding | aberrant positive regulation of chemorepellant activity | delayed aggregation | aberrant vegetative growth | delayed gene expression
DBS0350227 grlD-grlDaberrant positive regulation of chemorepellant activity | decreased growth rate | aberrant cytokinesis | abolished small molecule binding | aberrant cellular response to extracellular stimulus
DBS0236112 grlE-grlEdecreased spore cell differentiation | aberrant GABA signaling pathway | decreased sporulation
DBS0236113 grlE-grlEdelayed aggregation | aberrant gene expression | decreased chemotaxis to cAMP
DBS0350075 grlE-grlEdecreased spore germination | delayed aggregation
DBS0350226 grlH-grlHaberrant positive regulation of chemorepellant activity | aberrant protein level | aberrant vegetative growth | abolished activation of GTPase activity | decreased protein binding | increased growth rate
DBS0351147 grlH-/ [act15]: grlHgrlHwild type
DBS0238865 grlJ-grlJincreased migratory slug size | aberrant spore morphology | decreased spore germination | precocious development | decreased fruiting body size | precocious gene expression
DBS0350283 grlJ-grlJaberrant spore morphology | increased resistance to N-Phenylthiourea
DBS0238866 grlJ-/ [act15]: grlJ: GFPgrlJwild type
DBS0350284 grlJ-/ [act15]: grlJ: GFPgrlJwild type
DBS0238686 grpA-grpAdecreased spore germination | abolished protein secretion
DBS0238687 grpA-/ [act15]: grpA-FLAGgrpAwild type
ARK200 gskA-gskAabolished stream development | increased gene expression | decreased gene expression | increased protein localization to plasma membrane | decreased chemotaxis to cAMP | decreased sporulation
DBS0236114 gskA-gskAaberrant aggregation | decreased protein localization to cell cortex | decreased slug migration | aberrant sorus morphology | aberrant extracellular cAMP signaling pathway | decreased gene expression | abolished protein localization to plasma membrane | abolished protein phosphorylation | decreased chemotaxis to folate | decreased stalk length | abolished chemotaxis to cAMP
HM338 gskA-gskAprecocious aggregation | decreased prespore cell differentiation | aberrant mitotic spindle elongation | aberrant fruiting body morphogenesis | increased prestalk cell differentiation | decreased sporulation
DBS0349930 gskA-/ [act15]: GFP: tacAgskA | tacAincreased protein localization to nucleus
DBS0349881 gskA-/ [act15]: gskA(Y214F)gskAabolished stream development
DBS0349800 gskA-/ [ecmA]: LacZgskAaberrant prestalk gene expression
DBS0349801 gskA-/ [ecmB]: LacZgskAaberrant prestalk gene expression
DBS0350260 gskA-/ [unk]: pikA(1-492(S7D/ S11D/ S109D/ S113D/ S177D/ S181D))gskA | pikAwild type
DBS0350427 gskA-/ gskA(K85R): GFPgskAaberrant aggregation
DBS0350426 gskA-/ gskA: GFPgskAwild type
DBS0350988 gst4-gst4decreased fruiting body size
DBS0266891 gtaC-gtaCdecreased mound size | aberrant stream morphology | abolished stalk cell differentiation | aberrant prestalk B cell differentiation
DBS0350347 gtaC-gtaCabolished gene expression | decreased fruiting body size | abolished aggregation
DBS0350357 gtaC-/ [act15]: GFP: gtaC(C500,503,522,525S)gtaCaberrant gene expression | abolished aggregation | decreased fruiting body size
DBS0350358 gtaC-/ [act15]: GFP: gtaC(T376A/ S379,380A/ C500,503,522,525S)gtaCaberrant protein localization to nucleus
DBS0350361 gtaC-/ [act15]: gtaC: (468-496): GFP: gtaCgtaCdevelopment arrests at mound stage | decreased mound size | precocious development
DBS0351091 gtaG-gtaGdecreased gene expression | development arrests at slug stage | aberrant slug development | decreased prestalk A cell differentiation | decreased sporulation
DBS0236120 gxcA-gxcAdecreased activation of GTPase activity | decreased actin filament polymerization | delayed development
DBS0236121 gxcB-gxcBdecreased exocytosis | delayed development | aberrant cytoskeleton organization
DBS0350256 gxcC-gxcCdelayed development
DBS0350257 gxcC-/ [act15]: GFP: gxcCgxcCwild type
DBS0238825 gxcDD-gxcDDaberrant stream morphology | delayed development
LAS105 gxcKK-gxcKKdecreased socially cooperative development
DBS0350268 gxcT-gxcTaberrant activation of GTPase activity | increased lateral pseudopodium formation | aberrant cytokinesis | decreased growth rate | delayed aggregation | decreased establishment of cell polarity | decreased chemotaxis to cAMP | decreased fruiting body size | aberrant protein localization to plasma membrane
DBS0350269 gxcT-/ [act15]: GFP: gxcTgxcTwild type
DBS0350656 hatA-/ [hatB]: hatBhatA | hatBaberrant cellular response to stress
DBS0236129 hbx2-hbx2wild type
DBS0236130 hbx2-hbx2wild type
DBS0350324 hbx4-/ [ecmAO]: lacZhbx4increased prespore cell differentiation
DBS0350879 hbx9-hbx9decreased cell-cell adhesion | decreased gene expression | delayed aggregation | decreased growth rate | decreased chemotaxis to cAMP
DBS0350880 hbx9-/ [ecmA]: lacZhbx9increased prestalk A cell differentiation
DBS0236153 hcpA-hcpAdecreased growth rate
DBS0236157 hcpB-hcpBwild type
DBS0305109 hdaB-hdaBdecreased sporulation | decreased histone deacetylase activity
HM1012 helC-helCdecreased gene expression | delayed development | aberrant fruiting body morphogenesis
HM444 helC-helCdecreased gene expression | aberrant fruiting body morphogenesis | delayed development
DG1059 helE-helEincreased slug migration
DBS0236163 helF-helFincreased migratory slug size | increased stalk cell differentiation | delayed development | increased post-transciptional gene silencing by RNA
DBS0350878 hephA-hephAincreased response to cAMP | delayed aggregation | aberrant sorocarp development | decreased cAMP level
DBS0350362 hfnA-hfnAincreased phototaxis | decreased migratory slug size | increased slug migration
DBS0350363 hfnA-/ [ecmO]: lacZhfnAaberrant slug development | aberrant prestalk O cell differentiation
DBS0351593 hgrA-hgrA | matAaberrant macrocyst formation
DBS0351590 hgrA-/ KAX3hgrAaberrant macrocyst formation
DBS0351594 hgrB-hgrB | matAaberrant macrocyst formation
DBS0351591 hgrB-/ KAX3hgrBaberrant macrocyst formation
DBS0238583 hipA-hipAdecreased spore germination | aberrant spore morphology | aberrant cortical actin cytoskeleton organization | aberrant spore coat morphology | increased protein localization to plasma membrane
DBS0351165 hspb1-hsbp1-1 | hsbp1-2decreased exocytosis | decreased protein level | aberrant protein localization to lysosomal membrane
DBS0351532 hspc300-/ AX2hspc300aberrant macropinocytosis | aberrant cytokinesis | decreased cell motility | decreased filopodium formation | abolished protein level
DBS0350289 hspc300-/ [act15]: myc: hspc300hspc300wild type
DBS0252818 hssA-hssAwild type
DBS0351066 htmA-htmAdecreased gene expression | aberrant sorocarp development | increased cell-substrate adhesion | decreased cell motility
DBS0349776 htt-httaberrant cell separation during cytokinesis | decreased growth rate | decreased chemotaxis rate | delayed development | delayed gene expression | decreased myosin II assembly
DBS0349788 htt-httaberrant aggregation | abolished stream development | development arrests at loose mound stage | aberrant cellular response to starvation | aberrant spore morphology | decreased spore germination | abolished cell motility in response to calcium ion | increased number of mound tips | aberrant sorocarp development | aberrant hypotonic response | aberrant actin filament organization | abolished culmination | decreased sporulation | aberrant prespore cell differentiation | abolished calcium-independent cell-cell adhesion | abolished protein level | abolished chemotaxis to cAMP
DBS0351281 htt-httabolished gene expression | aberrant sorus morphology | decreased gene expression | decreased growth rate | aberrant slug development | aberrant sorocarp development | delayed development | decreased cAMP level | aberrant prestalk cell differentiation
DBS0350438 ibrA-ibrAaberrant substrate adhesion-dependent cell spreading | aberrant contractile vacuole organization | decreased phagocytosis | decreased growth rate | aberrant cytokinesis | aberrant hypotonic response | decreased contractile vacuole discharge
DBS0349794 ibrA-ibrAaberrant stalk development
DBS0252699 icmA-icmA-1 | icmA-2abolished sporulation | abolished stream development | aberrant extracellular cAMP signaling pathway | abolished establishment of cell polarity | development arrests at mound stage | abolished vegetative growth | aberrant oscillatory cAMP signaling | aberrant fruiting body morphogenesis | aberrant protein localization to nucleus | delayed gene expression | aberrant protein localization
DBS0252702 icmA-/ [act15]: TAP: YFP: rasGicmA-1 | icmA-2 | rasGabolished C-terminal protein methylation
DBS0252701 icmA-/ [act15]: hICMTicmA-1 | icmA-2wild type
DBS0252700 icmA-/ [act15]: icmAicmA-1 | icmA-2wild type
DBS0236421 icpA-icpAabolished protein localization to mitotic spindle | aberrant mitosis | aberrant cytokinesis | abolished protein localization to cleavage furrow | abolished protein localization to mitotic spindle midzone | aberrant protein localization
DBS0238521 icpA-/ [act15]: GFP: icpA(1-1013)icpAaberrant protein localization to mitotic spindle
BS153 ifkA-ifkAincreased mound size | precocious aggregation | precocious gene expression | decreased protein secretion
BS160 ifkB-ifkBincreased prestalk gene expression
DBS0236425 ino1-ino1increased number of mound tips | decreased phagocytosis | abolished vegetative growth | increased 2,3-bisphosphoglycerate level | decreased myo-inositol level
DBS0350801 ino1-ino1aberrant cellular metabolic process | increased number of autophagosomes | decreased cell-substrate adhesion | aberrant phosphatidylinositol metabolism | aberrant cytokinesis | abolished vegetative growth | aberrant fruiting body morphogenesis | decreased myo-inositol level
DBS0266326 iplA-iplAabolished cellulose biosynthesis | abolished autophagosome organization | abolished autophagic cell death | aberrant autophagic cell death
HM1038 iplA-iplAaberrant cell motility | precocious aggregation | delayed aggregation | aberrant chemotaxis | aberrant calcium-mediated signaling | increased bleb assembly | increased chemotaxis to arachidonic acid | abolished positive regulation of chemorepellant activity
DBS0351539 iplA-/ AX2iplAabolished response to DIF-1 | abolished response to cAMP | aberrant GABA signaling pathway
DBS0350439 iplA-/ [act15]: GFP: iplAiplAwild type
DBS0252878 iptA-iptAdecreased spore germination | aberrant sporulation
DBS0350400 iqgC-iqgCdecreased myosin II assembly
DBS0351225 iqgC-iqgCaberrant cytokinesis | increased macropinocytosis | increased phagocytosis
DBS0351435 ireA-ireAincreased number of autophagosomes | decreased protein level | aberrant vacuole organization | aberrant gene expression | aberrant cellular response to stress | aberrant endoplasmic reticulum organization | aberrant protein localization
DBS0351436 ireA-/ [act15]: ireA(K603N): GFPireAdecreased protein level | aberrant endoplasmic reticulum organization | aberrant cellular response to stress
DBS0351437 ireA-/ [act15]: ireA(N927A): GFPireAdecreased protein level | aberrant endoplasmic reticulum organization | aberrant cellular response to stress
DBS0236031 kctd9-kctd9wild type
DBS0350472 kif1-kif1aberrant transport
DBS0350959 kif10-/ [act15]: dhcA(1384-4725)dhcA | kif10wild type
DBS0350038 kif11-kif11wild type
DBS0236489 kif12-kif12aberrant protein localization to mitotic spindle | aberrant cell separation during cytokinesis | aberrant cytokinesis | aberrant myosin II filament organization | increased bleb assembly
DBS0236490 kif12-/ [act15]: FLAG: kif12kif12wild type
DBS0302534 kif13-kif13precocious mitotic spindle elongation | aberrant mitotic spindle organization
DBS0350039 kif4-kif4decreased growth rate
DBS0350042 kif4-/ [act15]: dhcA(1384-4725)dhcA | kif4aberrant mitotic spindle organization
DBS0350021 kif5-kif5wild type
DBS0350022 kif5-/ [act15]: FLAG: kif5kif5aberrant cytokinesis | aberrant cell morphology
DBS0350023 kif5-/ [act15]: FLAG: kif5(342-990)kif5aberrant cell morphology
DBS0350024 kif5-/ [act15]: GFP: kif5(805-990)kif5aberrant cytokinesis
DBS0236494 kif7-kif7decreased cell migration to prestalk region
DBS0350040 kif8-kif8aberrant microtubule cytoskeleton organization
DBS0350947 kif8-/ [act15]: dhcA(1384-4725)dhcA | kif8wild type
DBS0349964 kif9-kif9aberrant mitotic spindle organization | aberrant mitosis | decreased growth rate | aberrant protein localization to nuclear envelope | aberrant centrosome localization | aberrant centromere complex assembly | aberrant centrosome organization
DBS0236491 kil1-kil1abolished defense response to Gram-negative bacterium | increased defense response to fungus
DBS0350043 kil2-kil2aberrant response to cation stress | aberrant defense response to bacterium | decreased protein processing in phagocytic vesicle | abolished defense response to Gram-negative bacterium | increased defense response to fungus
DBS0350874 kil2-kil2aberrant defense response to bacterium | decreased growth rate
DBS0350044 kil2-/ [act15]: kil1kil1 | kil2abolished defense response to bacterium
DBS0351502 knkA-knkAdecreased spore germination | aberrant spore morphology | decreased number of autophagosomes | decreased prespore gene expression | aberrant fruiting body morphogenesis | aberrant phototaxis | decreased sporulation
DBS0236492 krsA-krsAdecreased chemotaxis to cAMP
DBS0238720 krsA-krsAabolished stream development | precocious culmination | abolished activation of adenylate cyclase activity | decreased vegetative cell size | decreased mound size | aberrant hyperosmotic response | precocious gene expression | decreased cAMP level
DBS0236493 krsA-/ [act15]: GFP: krsAkrsAwild type
DBS0238721 krsA-/ [act15]: GFP: krsAkrsAwild type
DBS0238722 krsA-/ [act15]: GFP: krsA(K49R)krsAaberrant stream morphology
DBS0238723 krsA-/ [act15]: GFP: krsA(T173A)krsAabolished stream development
DBS0238725 krsA-/ [act15]: GFP: krsA(deltaC)krsAaberrant stream morphology
DBS0238724 krsA-/ [act15]: GFP: krsA(deltaKinase)krsAabolished stream development
DBS0238726 krsA-/ [act15]: GFP: krsA(deltaNS)krsAabolished stream development
DBS0350598 krsB-krsBaberrant stream morphology | decreased cell motility | increased cell-substrate adhesion | delayed development | decreased chemotaxis to cAMP
DBS0350599 krsB-/ [tet]: krsB(T176A): GFPkrsBaberrant stream morphology
DBS0236495 ku80-ku80decreased resistance to bleomycin | decreased double-strand break repair via nonhomologous end joining
DBS0350537 ku80-/ myc: ku80(1-782)ku80decreased double-strand break repair via nonhomologous end joining
DBS0236498 lagD-tgrD1aberrant aggregation | abolished stream development | aberrant extracellular cAMP signaling pathway
DBS0236499 limB-limBdecreased cell-substrate adhesion | abolished cell migration to prestalk region | development arrests at mound stage | delayed prestalk gene expression | aberrant cell-cell adhesion | decreased prestalk gene expression | decreased chemotaxis rate | aberrant actin filament organization | decreased establishment of cell polarity
DBS0236502 limB-/ [act15]: paxB: GFPlimB | paxBdevelopment arrests at mound stage
DBS0236500 limB-/ [cotC]: limBlimBdevelopment arrests at mound stage
DBS0236501 limB-/ [ecmAO]: limBlimBwild type
DBS0350563 limC-limCdelayed aggregation | decreased growth rate | aberrant cytokinesis | aberrant response to osmotic stress
DBS0350564 limD1-limD1increased lateral pseudopodium formation | delayed aggregation | decreased growth rate | aberrant cytokinesis | aberrant response to osmotic stress | decreased chemotaxis to cAMP | decreased establishment of cell polarity | aberrant actin filament organization
DBS0236503 limE-limEaberrant cytokinesis
DBS0236506 limF-limFdecreased phagocytosis
DBS0236511 lipA-lipAwild type
DBS0236512 lipA-lipAwild type
DG1006 lipA-lipAabolished culmination
DG1056 lipB-captCaberrant fruiting body morphogenesis
DBS0349950 lmbd2B-lmbd2Baberrant chemotaxis | delayed development | aberrant cell morphology | increased pseudopodium formation
DBS0349982 lmnB-lmnBaberrant chromatin assembly | aberrant centrosome localization
DBS0350354 lmpA-lmpAdecreased lysosomal protein degradation | decreased pinocytosis | decreased protein level | decreased phagocytosis | decreased growth rate | decreased cell motility | decreased protein processing in phagocytic vesicle | aberrant phagosome maturation | decreased fruiting body size | decreased defense response to Gram-positive bacterium | decreased sporulation
DBS0351481 lmpB-lmpBdecreased phagocytosis
DBS0351482 lmpC-lmpCdecreased protein localization to cell surface | increased protein localization to cell surface
DBS0350452 lpten-lptenaberrant cell motility | decreased lateral pseudopodium retraction
DBS0350453 lpten-/ [act15]: lpten: RFPlptenwild type
DBS0236516 lrrA-lrrAincreased mound size | decreased spore germination | decreased cell-substrate adhesion | abolished establishment of cell polarity | decreased gene expression | development arrests at mound stage | increased actin filament polymerization | abolished positive chemotaxis | abolished aggregation | delayed gene expression
DBS0350407 lrrB-lrrBaberrant thermotaxis | delayed slug development | aberrant gene expression | aberrant sorocarp development | decreased prestalk gene expression | aberrant phototaxis | aberrant late culminant morphology
DBS0350478 lrrB-/ [ecmB]: lacZlrrBaberrant prestalk B cell differentiation
DBS0350476 lrrB-/ [ecmO]: lacZlrrBaberrant prestalk O cell differentiation
DBS0351456 lrrkA-drkDaberrant defense response to bacterium | decreased protein processing in phagocytic vesicle | abolished vegetative growth
DBS0236517 lst8-lst8aberrant activation of adenylate cyclase activity | decreased actin filament polymerization | decreased chemotaxis rate | abolished aggregation | decreased myosin II assembly | abolished positive regulation of chemorepellant activity
DBS0350106 lst8-lst8increased phagocytosis
DBS0350114 lst8-/ [act15]: GFP: rheb(Q64L)lst8 | rhebincreased phagocytosis
DBS0309063 lvsA-lvsAincreased bleb assembly
AD60 lvsA-lvsAabolished cytokinesis | decreased pinocytosis | aberrant contractile vacuole organization | decreased phagocytosis | aberrant hypotonic response | increased cell-substrate adhesion
AD63 lvsA-lvsAabolished cytokinesis | abolished contractile vacuole dissociation from plasma membrane | aberrant calcium-mediated signaling
DBS0236521 lvsB-lvsBincreased secretion of lysosomal enzymes | increased lysosome size | increased exocytosis | increased pinocytosis | aberrant protein localization to post-lysosomal vacuole | aberrant phagosome maturation | increased endosome size | aberrant post-lysosomal vacuole exocytosis | increased endosomal vesicle fusion | aberrant lysosome organization
DBS0350567 lvsB-/ [act15]: FLAG: Rab14(N121I)lvsB | rab14wild type
DBS0236522 lvsC-lvsCwild type
DBS0236523 lvsD-lvsDwild type
DBS0236524 lvsE-lvsEwild type
DBS0236525 lvsF-lvsFwild type
DBS0351162 lyC2-lyC2decreased growth rate
DBS0349933 macA-macAaberrant macrocyst formation | decreased sexual fusion
DBS0236536 malA-malAwild type
DBS0351251 matA-matAabolished mating type determination
HM1524 matA-matAabolished mating type determination
DBS0350211 mef2A-mef2Adecreased growth rate | aberrant sorocarp development | aberrant stream morphology | decreased sporulation
DBS0350212 mef2A-mef2Adecreased growth rate | aberrant stream morphology | aberrant sorocarp development | aberrant gene expression | decreased sporulation
DBS0350213 mef2A-/ [ecmA]: lacZmef2Aaberrant prestalk A cell differentiation
DBS0350214 mef2A-/ [ecmB]: lacZmef2Aaberrant prestalk B cell differentiation
DBS0350215 mef2A-/ [pspA]: lacZmef2Adecreased prespore cell differentiation
DBS0236543 mekA-mekAdecreased mound size | precocious development | abolished chemotaxis to cAMP
DBS0350030 mekA-/ [act15]: Myc: erkAerkA | mekAabolished protein localization to cell cortex
DBS0350036 mekA-/ [act15]: mekA(299-360)mekAdecreased mound size
DBS0350035 mekA-/ [act15]: mekA(K321A)mekAdecreased mound size
DBS0350032 mekA-/ [act15]: mekA(S444A/ T448A)mekAdecreased mound size
DBS0350031 mekA-/ [act15]: mekA(S444E/ T448E)mekAdevelopment arrests at mound stage
DBS0236544 mfeA-mfeAaberrant cellular metabolic process | decreased protein level | aberrant extracellular cAMP signaling pathway | development arrests at mound stage
DBS0351543 mfsd8-mfsd8increased protein secretion
DBS0266843 mgp1-mgp1increased phototaxis | abolished stream development | increased filopodium formation | aberrant contractile vacuole organization | decreased cell motility | decreased fruiting body size | decreased stalk width | decreased stalk length
DBS0266846 mgp1-/ mgp2-mgp1 | mgp2increased filopodium formation | aberrant contractile vacuole organization | aberrant culmination | decreased cell motility | decreased phototaxis | decreased stalk length
DBS0266844 mgp2-mgp2increased migratory slug size | increased mound size
HS1 mhcA-mhcAdevelopment arrests at mound stage | aberrant cytokinesis | decreased growth rate | increased actin filament polymerization | aberrant hypotonic response | aberrant regulation of GTPase activity | abolished bleb assembly | aberrant regulation of protein kinase activity | aberrant cellular response to stress
HS2205 mhcA-mhcAabolished cell motility | decreased cell motility
HS2207 mhcA-mhcAabolished cytokinesis | development arrests at mound stage
DBS0350064 mhcA-mhcAdecreased cell motility | decreased establishment of cell polarity
HS2206 mhcA-mhcAaberrant cellular response to fluid shear stress | abolished bleb assembly
HK321 mhcA-mhcAaberrant cortical actin cytoskeleton organization | aberrant chemotaxis to folate | aberrant cell morphology
HK323 mhcA-mhcAdecreased cell motility | aberrant stream morphology
DBS0266674 mhcA-/ [act15]: GFP: abpC(9-148)abpC | mhcAdecreased uropod retraction | decreased pseudopodium retraction
DBS0237564 mhcA-/ [act15]: GFP: ctxA/ [RNAi]enlActxA | enlA | mhcAaberrant mitotic actomyosin contractile ring contraction
DBS0266675 mhcA-/ [act15]: GFP: mhcA(E476K)mhcAdecreased pseudopodium retraction
DBS0350489 mhcA-/ [act15]: GFP: mhcA/ [RNAi]rmd1mhcA | rmd1abolished protein localization to cleavage furrow
DBS0236548 mhcA-/ [act15]: GFP: pats1(2087-2351)mhcA | pats1aberrant cytokinesis
DBS0350291 mhcA-/ [act15]: gppA: GFPgppA | mhcAaberrant contractile vacuole morphology | decreased contractile vacuole discharge
DBS0236549 mhcA-/ [act15]: limE(1-145): GFPlimE | mhcAincreased actin filament polymerization
DBS0350808 mhcA-/ [act15]: mhcA(1-933: 1455-2116]mhcAwild type | aberrant cytokinesis | aberrant fruiting body morphogenesis
DBS0238158 mhcA-/ [act15]: mhcA(81-2116)mhcAdecreased growth rate | development arrests at tipped mound stage
CW0401 mhcA-/ [act15]: mhcA(T1823A/ T1833A/ T2029A)mhcAincreased myosin II assembly | decreased growth rate | aberrant chemotaxis
DBS0236550 mhcA-/ [act15]: mhcA(T1823A/ T1833A/ T2029A)mhcAdecreased filopodium formation
DBS0236551 mhcA-/ [act15]: mhcA(T1823D/ T1833D/ T2029D)mhcAincreased filopodium formation
DBS0238399 mhcA-/ [act15]: rapA(G12V)mhcA | rapAincreased establishment of cell polarity | increased actin filament polymerization | aberrant myosin II filament organization
DBS0236552 mhcA-/ [mhcA]: mhcA(1-1224)mhcAaberrant cytokinesis | development arrests at mound stage
DBS0350948 mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(E683K)mhcAaberrant catalytic activity
DBS0350949 mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R686C)mhcAaberrant catalytic activity
DBS0238157 mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R689H)mhcAdecreased actin filament sliding
DBS0236547 mhcA-/ [unk]: GFP: icpAicpA | mhcAdecreased protein localization to cleavage furrow
CW0371 mhkA-mhkAincreased myosin II assembly | aberrant chemotaxis | decreased cell motility | aberrant protein localization to pseudopodium
DBS0236557 mhkA-/ [act15]: mhkAmhkAdecreased growth rate | development arrests at mound stage | aberrant cytokinesis | decreased myosin II assembly
CW0166 mhkB-mhkBincreased myosin II assembly | decreased cell motility
CW0403 mhkC-mhkCincreased myosin II assembly | aberrant cytokinesis | aberrant chemotaxis
DG1069 mhkC-mhkCaberrant fruiting body morphogenesis
CW0435 mhkD-mhkDincreased myosin II assembly | decreased cell motility
DBS0236559 midA-midAdecreased pinocytosis | aberrant cellular homeostasis | aberrant spore morphology | decreased glycogen level | increased ammonia level | decreased thermotaxis | increased autophagy | decreased mitochondrial fission | decreased growth rate | decreased phagocytosis | decreased vegetative cell size | increased slug migration | increased glutamate level | decreased phototaxis
DBS0350123 midA-/ [act15]: GFP: atg18atg18 | midAincreased number of autophagosomes
DBS0350136 midA-/ [act15]: GFP: tktmidA | tkt-1 | tkt-2increased autophagy
DBS0351180 midA/ [act15]: midA(E200A)midAaberrant cellular homeostasis | decreased growth rate | decreased phototaxis
DBS0351182 midA/ [act15]: midA(G170V/ G172V)midAaberrant cellular homeostasis | decreased growth rate | decreased phototaxis
DBS0351181 midA/ [act15]: midA(N205A)midAaberrant cellular homeostasis | decreased growth rate | decreased phototaxis
DG1020 migA-migAabolished slug migration | decreased mound size | aberrant fruiting body morphogenesis | decreased fruiting body size
DBS0350958 migA-migAdecreased gene expression | aberrant chemotaxis to cAMP
DBS0350025 mip1-mip1-1 | mip1-2increased mound size | decreased chemotaxis to cAMP
DBS0350027 mip1-/ [act15]: mekA: FLAGmekA | mip1-1 | mip1-2aberrant protein localization to cytoplasm
DBS0266620 mipp1-mipp1aberrant inositol phosphate metabolic process | increased response to lithium
DBS0236560 mkcA-mkcAdecreased prestalk gene expression
DG1101 mkcB-mkcBdecreased fruiting body size
DBS0236564 mkkA-mkkAprecocious culmination | decreased sorus size | increased stalk length
DG1121 mkpA-mkpAabolished aggregation
DBS0236566 mlcE-mlcEaberrant cytokinesis | decreased growth rate | delayed aggregation | aberrant taxis | aberrant sorocarp development | decreased cell motility | aberrant gene expression
DBS0238058 mlcE-/ [act15]: myc: mlcEmlcEwild type
DBS0236567 mlcR-mlcRaberrant cytokinesis | development arrests at mound stage | aberrant myosin II filament organization
DBS0351550 mlcR-/ [ecmAO]: GFPmlcRaberrant development of tipped mound
HS183 mlkA-mlkAaberrant cytokinesis
DBS0349919 mlkA-/ [act15]: GFP-mhcAmlkAaberrant stalk morphogenesis
DG1033 modA-modAdecreased response to Gram-negative bacterium | abolished catalytic activity | aberrant fruiting body morphogenesis
DBS0266903 mpl1-mpl1abolished stream development | decreased cell motility | decreased chemotaxis to cAMP | abolished aggregation
DBS0266904 mpl1-/ [act15]: flag: mpl1mpl1wild type
DBS0349986 mrfA-mrfAaberrant slug migration | delayed development
DBS0350391 mrfA-/ [act15]: myc: mrfA(K772A): FLAGmrfAaberrant protein modification
DBS0350390 mrfA-/ [act15]: myc: mrfA(S767A): FLAGmrfAaberrant protein modification | delayed development
DBS0350389 mrfA-/ [act15]: myc: mrfA: FLAGmrfAwild type
DBS0349987 mrfA-/ [emcA]: lacZmrfAdecreased prestalk A cell differentiation
DBS0350960 mroh1-mroh1aberrant exocytosis | decreased lysosome size
DBS0236569 mrps4-mrps4delayed aggregation | aberrant fruiting body morphogenesis
DBS0350868 mtpn-mtpndecreased actin filament polymerization | decreased growth rate | decreased cell motility | aberrant stream morphology | decreased macropinocytosis
HM1464 mus81-mus81wild type
DBS0350866 mvpA-mvpAaberrant cell morphology
DBS0236570 mybB-mybBdecreased gene expression | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | abolished aggregation
DBS0236571 mybB-mybBabolished aggregation
HM388 mybC-mybCdecreased gene expression | development arrests at slug stage | decreased prespore gene expression | abolished culmination
DBS0236572 mybE-mybEincreased migratory slug size | increased gene expression | abolished outer basal disc formation
DBS0237709 mybE-/ [mrrA]: lacZmrrA | mybEaberrant prestalk cell differentiation
DBS0236573 mybE-/ mybE: GFPmybEwild type | aberrant prestalk cell differentiation
HDT1 myoA-myoAaberrant aggregation | decreased lateral pseudopodium retraction | delayed aggregation | decreased cell motility | decreased chemotaxis rate | aberrant pseudopodium formation | decreased chemotaxis to cAMP
HDT2 myoA-myoAincreased secretion of lysosomal enzymes | delayed aggregation
DBS0236579 myoB-myoBincreased secretion of lysosomal enzymes | aberrant aggregation | decreased lateral pseudopodium retraction | decreased cell motility | decreased chemotaxis to cAMP
DBS0236580 myoB-myoBincreased lateral pseudopodium formation | decreased phagocytosis | delayed aggregation | decreased cell motility
DBS0349853 myoB-myoBdecreased phagolysosome size | delayed phagosome reneutralization | aberrant phagosome maturation
DBS0236583 myoB-/ [AS]myoDmyoB | myoDdecreased pinocytosis | aberrant aggregation | decreased growth rate | decreased phagocytosis | decreased mound size | decreased cell motility
DBS0236584 myoB-/ [AS]myoD/ [KD]myoCmyoB | myoC | myoDdecreased pinocytosis | aberrant aggregation | decreased pinosome size | decreased growth rate | decreased phagocytosis | decreased mound size | decreased cell motility | increased number of pinosomes
DBS0351378 myoB-/ [act15]: GFP: myoB(1-720)myoBabolished protein localization to plasma membrane
DBS0351379 myoB-/ [act15]: GFP: myoB(1-800,813-1111)myoBabolished protein localization to actin wave | abolished protein localization to plasma membrane
DBS0351380 myoB-/ [act15]: GFP: myoB(713-1111)myoBabolished protein localization to leading edge
DBS0351367 myoB-/ [act15]: myoB(S332A)myoBabolished protein phosphorylation
DBS0236585 myoC-myoCdecreased phagocytosis
HDT4 myoC-myoCdecreased pinocytosis | decreased phagocytosis
DBS0236587 myoD-myoDwild type
HDT8 myoF-myoFaberrant aggregation | wild type | increased lateral pseudopodium formation | decreased cell motility | decreased chemotaxis to cAMP | aberrant cell morphology
DBS0350251 myoG-myoGdecreased protein localization to plasma membrane | decreased actin filament polymerization | abolished establishment of cell polarity | aberrant chemotaxis to cAMP | abolished aggregation
DBS0236589 myoI-myoIdecreased spore germination
DBS0236592 myoI-myoIdecreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | aberrant cell morphology
HDT15 myoI-myoIdecreased phagocytosis
HDT17 myoI-myoIdecreased cell-cell adhesion | decreased protein level | decreased cell-substrate adhesion | decreased phagocytosis | decreased filopodium formation
DBS0266889 myoI-/ [act15]: GFP: myoImyoIwild type
DBS0351400 myoI-/ [act15]: GFP: myoI(1-1020)myoIabolished protein localization to pseudopodium | decreased filopodium formation
DBS0351398 myoI-/ [act15]: GFP: myoI(2057-2357)myoIincreased filopodium formation
DBS0266890 myoI-/ [act15]: GFP: myoI(809-1154)myoIdecreased phagocytosis
DBS0351399 myoI-/ [act15]: GFP: myoI(K23333A,K2336A)myoIincreased filopodium formation
DBS0237617 myoI-/ [act15]: gbpDgbpD | myoIincreased cell-substrate adhesion | aberrant cell morphology | increased pseudopodium formation
HTD7 myoJ-myoJwild type
DBS0350931 myoJ-myoJdecreased hypotonic response | aberrant contractile vacuole discharge | aberrant contractile vacuole localization
DBS0349844 myoK-myoKaberrant cortical actin cytoskeleton organization | delayed aggregation | decreased phagocytosis | aberrant engulfment during phagocytosis | aberrant phagosome maturation | decreased chemotaxis rate | aberrant cell morphology | delayed phagosome acidification
DBS0349846 myoK-/ [act15]: YFP: myoK(1-121: 262-858)myoKdecreased phagocytosis
DBS0349850 myoK-/ [act15]: myoKmyoKincreased phagocytosis
DBS0349854 myoK-/ [act15]: pakB(1-337: 563-852)myoK | pakBwild type
DBS0236595 myoM-myoMwild type
DBS0351046 nad2-nad2decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant fruiting body morphogenesis | aberrant phototaxis
DBS0351048 nad5-nad5decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis
AK1372 nagB1-nagB1decreased response to Gram-positive bacterium
DBS0236596 napA-napAaberrant cellular response to extracellular stimulus
SB12 napA-napAdecreased cell-cell adhesion | decreased cell-substrate adhesion | decreased actin filament polymerization | decreased cell motility | decreased vegetative cell size | decreased establishment of cell polarity | decreased phototaxis
DBS0351534 napA-/ AX2napAdecreased protein level | increased membrane ruffling | aberrant cytokinesis | increased vegetative cell size | decreased cell motility
HC476 ncsA-ncsAincreased cAMP level | precocious gene expression | precocious development
HC477 ncsA-ncsAincreased cAMP level | precocious gene expression | precocious development
DBS0350297 ncstn-ncstnaberrant culmination | abolished catalytic activity | decreased prespore cell differentiation
DBS0350307 ncstn-ncstnwild type | aberrant sorocarp development | decreased macropinocytosis
DBS0349947 ndm-ndmaberrant chemotaxis | increased pinocytosis | decreased fruiting body size | aberrant pseudopodium formation
DBS0349895 ndrA-ndrAdecreased engulfment during phagocytosis
DBS0349896 ndrA-/ [unk]: GFP: ndrAndrAwild type
DBS0350446 ndrC-ndrCincreased positive regulation of GTPase activity | increased number of centrosomes | aberrant cell separation during cytokinesis
DBS0350121 ndufaf5-ndufaf5aberrant spore morphology | decreased growth rate | delayed development | aberrant phototaxis | decreased fruiting body size | decreased sporulation
DBS0350125 ndufaf5--/ [act15]: ndufaf5(G86V): GFP: TAPndufaf5decreased growth rate
DBS0350126 ndufaf5--/ [act15]: ndufaf5(L165F): GFP: TAPndufaf5decreased growth rate
DBS0350127 ndufaf5--/ [act15]: ndufaf5(L235P): GFP: TAPndufaf5decreased growth rate
DBS0350124 ndufaf5--/ [act15]: ndufaf5: GFP: TAPndufaf5wild type
DBS0350122 ndufaf5-/ [act15]: GFP: atg18atg18 | ndufaf5increased number of autophagosomes
DBS0350134 ndufaf5-/ [act15]: GFP: tktndufaf5 | tkt-1 | tkt-2increased autophagy
DBS0350137 ndufaf5-/ [act15]: [AS]snfAndufaf5 | snfAaberrant phototaxis
DBS0304633 nfaA-nfaAaberrant extracellular cAMP signaling pathway | aberrant activation of GTPase activity | increased actin filament polymerization | delayed aggregation | decreased cell motility | aberrant regulation of GTPase activity | aberrant regulation of protein kinase activity | aberrant protein localization to plasma membrane | decreased chemotaxis to cAMP | increased pseudopodium formation
DBS0351061 ngap-ngapaberrant regulation of fruiting body formation | aberrant extracellular cAMP signaling pathway | aberrant adaptation of signaling pathway | increased actin filament polymerization | aberrant chemotaxis to cAMP | aberrant regulation of protein kinase activity | decreased establishment of cell polarity | increased activation of GTPase activity
DBS0236604 nhe1-nhe1abolished cell motility in response to calcium ion | decreased intracellular pH | abolished establishment of cell polarity | decreased actin filament polymerization | decreased chemotaxis rate | delayed development | aberrant actin filament organization | decreased establishment of cell polarity | abolished chemotaxis to cAMP
DBS0350003 nhe1-/ [act15]: GFP: aip1aip1 | nhe1decreased establishment of cell polarity | decreased chemotaxis to cAMP
DBS0350006 nhe1-/ [act15]: GFP: aip1(E125A, E167A, F181A, F193A)aip1 | nhe1abolished aggregation | abolished chemotaxis to cAMP
DBS0350001 nhe1-/ [act15]: aip1(168-597)aip1 | nhe1delayed development
DBS0350002 nhe1-/ [act15]: aip1(383-597): FLAGaip1 | nhe1decreased actin filament polymerization | abolished establishment of cell polarity | abolished chemotaxis to cAMP
DBS0349841 nhe1-/ [act15]: mhcA: GFPmhcA | nhe1abolished protein localization to trailing edge
DBS0236605 nhe1-/ [act15]: nhe1: HAnhe1wild type
DBS0350508 nlp-nlpwild type
DBS0236606 nosA null (15-S-12)nosAdevelopment arrests at mound stage
DBS0236607 nosA null (2E4)nosAdevelopment arrests at mound stage
DBS0235950 nosA-nosAdevelopment arrests at mound stage | aberrant protein modification
DBS0236608 noxA-noxAabolished sporulation | aberrant sorocarp development
DBS0236611 noxA-/ [act15]: noxA: myc2noxAaberrant fruiting body morphogenesis
DBS0236612 noxB-noxBabolished sporulation | aberrant sorocarp development | decreased superoxide generation
DBS0236613 noxC-noxCabolished sporulation | aberrant sorocarp development
DBS0238849 npcA-npcAwild type
HSB60 nramp1-nramp1decreased defense response to Gram-negative bacterium | decreased defense response to Gram-positive bacterium | abolished iron ion transport
DBS0236696 nramp1-/ [act15]: nramp1: GFPnramp1increased defense response to Gram-negative bacterium
DBS0236697 nramp1-/ [act15]: nramp1: GFPnramp1increased defense response to Gram-negative bacterium
DBS0350092 nrampB-nrampBdecreased defense response to Gram-negative bacterium | delayed aggregation
DBS0236955 nxnA-nxnAdecreased lysosomal protein degradation | decreased culmination | decreased growth rate | delayed development | decreased chemotaxis to cAMP
DBS0351164 nxnA-nxnAaberrant cellular response to stress
DBS0236702 nxnA-/ [act15]: GFP: nxnB nxnA | nxnBdevelopment arrests at mound stage
DBS0350857 odc-odcaberrant cellular metabolic process | aberrant cell cycle | abolished vegetative growth
DBS0236704 osbA-osbAincreased slug migration | precocious development
DBS0238357 p2xA-p2xAaberrant hypotonic response
DBS0304487 p2xA-p2xAwild type
DBS0350312 p2xA-p2xAaberrant contractile vacuole organization | abolished hypotonic response | decreased contractile vacuole size | aberrant regulation of GTPase activity
DBS0350484 p2xA-/ AX2p2xAwild type | aberrant contractile vacuole discharge
DBS0350485 p2xA-/ AX4p2xAaberrant contractile vacuole discharge | aberrant hypotonic response
DBS0238362 p2xA-/ [act15]: p2xA: GFPp2xAwild type
DBS0350315 p2xA-/ p2xA(K67A/ K289A)p2xAabolished hypotonic response
DBS0350314 p2xA-/ p2xA(R285K)p2xAdecreased hypotonic response
DBS0350313 p2xA-/ p2xA(R63A)p2xAprecocious hypotonic response
DBS0306166 p2xB-p2xBwild type
DBS0306167 p2xC-p2xCwild type
DBS0306168 p2xD-p2xDwild type
DBS0304486 p2xE-p2xEwild type
DBS0350013 pah-pahabolished catalytic activity | abolished vegetative growth
DBS0350014 pah-/ [act15]: 6xHis: pahpahwild type
DBS0350016 pah-/ [act15]: 6xHis: pah(92-415)pahabolished vegetative growth
DBS0350015 pah-/ [act15]: 6xHis: pah(92-441)pahwild type
DBS0236705 pakA-pakAaberrant cytokinesis | delayed development | decreased myosin II assembly
DBS0236706 pakA-pakAwild type
DBS0349885 pakA-pakAdelayed development | decreased chemotaxis to cAMP | increased bleb assembly
DBS0236707 pakA-/ [act15]: pakApakAwild type
DBS0350810 pakA-/ [act15]: pakA(T579A)pakAdecreased chemotaxis to cAMP
DBS0236709 pakB-pakBdecreased growth rate | decreased bleb assembly
DBS0236708 pakB-pakBabolished establishment of cell polarity | decreased lateral pseudopodium retraction
DBS0236712 pakB-/ [act15]: GFP-pak(1-600)pakBabolished cytokinesis
DBS0236710 pakB-/ [act15]: GFP-pakB(1-337: 563-851)pakBabolished cytokinesis | increased pinocytosis | increased phagocytosis
DBS0350428 pakB-/ [act15]: RFP: abpEabpE-1 | abpE-2 | pakBdecreased chemotaxis to cAMP | aberrant establishment or maintenance of cell polarity | abolished aggregation | abolished protein localization to leading edge
DBS0350430 pakB-/ [act15]: RFP: abpE/ [act15]: GFP: pak(1-180)abpE-1 | abpE-2 | pakBwild type
DBS0236716 pakC-pakCdecreased lateral pseudopodium retraction | decreased bleb assembly | decreased chemotaxis rate
DBS0350281 pakD-pakDaberrant cellular homeostasis | aberrant filopodium formation | aberrant actin cytoskeleton organization | abolished negative regulation of vegetative growth | abolished aggregation | aberrant actin filament polymerization | aberrant establishment or maintenance of cell polarity | decreased chemotaxis to cAMP | increased growth rate | aberrant cellular response to extracellular stimulus | abolished positive regulation of chemorepellant activity
DBS0350282 pakD-/ [act15]: pakDpakDdevelopment arrests at mound stage
DBS0350395 pakD-/ [act15]: pakD: GFPpakDwild type
HC392 patB-patBabolished vegetative growth
DBS0236726 pats1-pats1aberrant cytokinesis
DBS0350097 pats1-pats1aberrant cytokinesis
LAS45 pats1-pats1decreased socially cooperative development
DBS0236727 pats1-/ [act15]: GFP: pats1(2087-2351)pats1aberrant cytokinesis
DBS0236728 paxB-paxBdecreased exocytosis | decreased cell-substrate adhesion | abolished slug migration | increased chemotaxis to cAMP | development arrests at mound stage | decreased prespore gene expression | aberrant fruiting body morphogenesis | decreased cell migration to prestalk region | increased phagocytosis
DBS0304926 paxB-paxBaberrant cell separation during cytokinesis | decreased cell-substrate adhesion | aberrant cytokinesis | decreased cell motility
DBS0304930 paxB-/ [act15]: GFP: paxBpaxBwild type
DBS0350973 paxB-/ [act15]: gpaHgpaH | paxBaberrant cytokinesis
DBS0350094 paxB-/ [act15]: pldBpaxB | pldBwild type | increased phagocytosis
DBS0236730 paxB-/ [ecmA]: paxB: GFPpaxBdecreased cell migration to prestalk region
DBS0236732 paxB-/ [pspA]: paxB: GFPpaxBdecreased cell migration to prestalk region
DBS0236733 pcp-pcpwild type | aberrant hypotonic response
DBS0236734 pde4-pde4decreased culmination | abolished stream development | delayed slug development | increased number of early culminant tips | increased protein level | delayed culmination
DBS0236735 pde4-/ [act15]: pde4: GFPpde4wild type
DBS0235991 pdeD-pdeDdecreased 3',5'-cyclic-GMP phosphodiesterase activity
DBS0236736 pdeD-pdeDaberrant calcium-mediated signaling
DBS0350517 pdeD-pdeDdecreased 3',5'-cyclic-GMP phosphodiesterase activity | increased fruiting body size | aberrant stream morphology
DBS0351194 pdeD-pdeDdecreased protein localization to cell cortex | abolished protein localization to cell cortex | aberrant chemotaxis to cAMP | aberrant actin filament polymerization | decreased myosin II assembly | increased activation of GTPase activity
DBS0350518 pdeD-/ [act15]: pdeD: YFPpdeDwild type
DBS0350900 pdeE-pdeEincreased oscillatory cAMP signaling | abolished 3',5'-cyclic-AMP phosphodiesterase activity
DBS0235993 pdeE-pdeEdecreased 3',5'-cyclic-AMP phosphodiesterase activity | aberrant chemotaxis to cAMP
DBS0236740 pdiA-pdiAdecreased mound size | aberrant oscillatory cAMP signaling | decreased fruiting body size
DBS0350797 pdkA-pdkAaberrant macropinocytosis | decreased protein kinase activation
DBS0350817 pdkA-pdkAdecreased mound size | decreased protein kinase activation
DBS0350798 pdkB-pdkBincreased macropinocytosis
DBS0350818 pdkB-pdkBdecreased mound size
DBS0237029 pdsA-pdsAaberrant chemotaxis to cAMP | aberrant stream morphology
UK7 pdsA-pdsAdecreased 3',5'-cyclic-AMP phosphodiesterase activity | decreased gene expression | aberrant sorocarp development | abolished aggregation
DBS0236741 pefA-pefAwild type
DBS0236744 pefB-pefBwild type
HW260 pgtA-pgtAincreased vegetative cell size
DBS0305022 pgtB-pgtBaberrant cellular metabolic process | aberrant spore coat morphology | aberrant hyperosmotic response
DBS0305023 pgtC-pgtCaberrant cellular metabolic process | aberrant hyperosmotic response
DBS0236752 phdA-phdAdecreased actin filament polymerization | decreased mound size | decreased chemotaxis rate | decreased fruiting body size
DBS0236753 phdA-/ [act15]: phdAphdAwild type
DBS0236754 phdA-/ [act15]: phdA: GFPphdAwild type
DBS0350865 phdG-phdGdecreased chemotaxis to cAMP
DBS0236755 phg1A-phg1Aincreased secretion of lysosomal enzymes | decreased lysosomal protein degradation | decreased protein level | decreased cell-substrate adhesion | decreased gene expression | aberrant defense response to bacterium | aberrant cytokinesis | decreased phagocytosis | abolished defense response to bacterium | decreased growth rate | development arrests at slug stage | decreased protein localization to cell surface | aberrant phagocytosis | increased lysosomal pH | decreased protein stabilization
DBS0351549 phg1A-phg1Adecreased cell-substrate adhesion | decreased phagocytosis
DBS0236757 phg1A-/ [act15]: kil1kil1 | phg1Adecreased lysosomal protein degradation | increased secretion of lysosomal enzymes | wild type | increased lysosomal pH | decreased protein stabilization
DBS0304869 phg1A-/ [act15]: phg1A(1-276): phg1B221-587)phg1A | phg1Bdecreased phagocytosis
DBS0304868 phg1A-/ [act15]: phg1Bphg1A | phg1Bincreased secretion of lysosomal enzymes | wild type | decreased cell-substrate adhesion | aberrant protein level | decreased phagocytosis
DBS0304870 phg1A-/ [act15]: phg1B(1-220): phg1a(277-642)phg1A | phg1Bdecreased phagocytosis
DBS0304866 phg1B-phg1Bincreased secretion of lysosomal enzymes | decreased protein level | decreased phagocytosis | decreased growth rate | abolished culmination
DBS0236758 phg2-phg2decreased cell-substrate adhesion | decreased phagocytosis | aberrant cytokinesis | decreased cell motility | aberrant cell morphology | aberrant actin filament organization | precocious development | precocious gene expression | aberrant response to nutrient
DBS0238400 phg2-phg2increased filopodium formation | increased actin filament polymerization | increased cell-substrate adhesion | decreased chemotaxis to cAMP | aberrant cell morphology | increased phagocytosis
DBS0350578 phg2-phg2abolished gene expression | decreased protein phosphorylation | aberrant protein localization to nucleus
DBS0236760 phg2-/ [act15]: GFP: phg2(199-1389)phg2decreased phagocytosis
DBS0237615 phg2-/ [act15]: gbpDgbpD | phg2aberrant cell morphology | abolished chemotaxis to cAMP | increased pseudopodium formation
DBS0350580 phg2-/ [act15]: myc: ptpCphg2 | ptpCabolished protein phosphorylation
HG1648 phgA-phgAincreased contractile vacuole size | aberrant contractile vacuole organization | aberrant hypotonic response | aberrant pore formation during contractile vacuole discharge
DBS0302610 phgA-/ [OE]: dsggdsgg | phgAaberrant contractile vacuole organization
DBS0236761 phgA-/ lvsA-/ [act6]: GFP: lvsAlvsA | phgAaberrant protein localization to contractile vacuole
DBS0236762 phlp1-phlp1decreased response to cAMP | aberrant regulation of protein modification | abolished chemotaxis to folate | decreased growth rate | abolished protein localization to plasma membrane | decreased cGMP-mediated signaling | abolished aggregation | abolished chemotaxis to cAMP
DBS0236763 phlp1-/ [OE]: phpl1phlp1wild type
DBS0236764 phlp3-phlp3wild type
DBS0350824 phr-phraberrant chemotaxis to cAMP | delayed development
HW288 phyA-phyAabolished sporulation | abolished stalk development | abolished peptidyl-proline hydroxylation | abolished culmination | increased response to hypoxia
DBS0266771 phyA-/ [ecmA]: phyA(D132N): mycphyAdecreased peptidyl-proline hydroxylation
DBS0266770 phyA-/ [ecmA]: phyA(R276A): mycphyAabolished peptidyl-proline hydroxylation | abolished culmination
DBS0236767 piaA-piaAaberrant activation of adenylate cyclase activity
DBS0236770 piaA-piaAaberrant cytokinesis
DBS0236771 piaA-piaAabolished aggregation | decreased myosin II assembly | increased phagocytosis
DBS0304637 piaA-piaAdecreased cell motility | decreased chemotaxis rate | decreased establishment of cell polarity | aberrant protein tyrosine phosphorylation
DBS0351319 piaA-piaAdecreased taxis
DBS0349879 piaA-piaAdecreased protein phosphorylation | decreased protein kinase activity | abolished protein phosphorylation | decreased chemotaxis to cAMP | aberrant protein localization to plasma membrane | increased activation of GTPase activity | abolished positive regulation of chemorepellant activity
DBS0351403 piaA-piaAaberrant cytokinesis
DBS0236779 pik6-pik6decreased gene expression | abolished aggregation
DBS0236772 pikA-pikAwild type
DBS0236774 pikB-pikBwild type
DBS0236776 pikC-pikCwild type
DBS0236777 pikD1pikDabolished slug migration | delayed aggregation | decreased mound size | aberrant fruiting body morphogenesis | decreased sporulation
DBS0236778 pikE-pikEwild type
HM1241 pikF-pikFdecreased pinocytosis | decreased growth rate | aberrant pinosome maturation
LAS31 pikG-pikGaberrant socially cooperative development
HM1513 pikI-pikIdecreased catalytic activity | decreased actin filament polymerization | decreased growth rate | aberrant chemotaxis to cAMP | decreased cGMP-mediated signaling | aberrant calcium-mediated signaling | decreased protein kinase activation | increased bleb assembly
DBS0350828 pinA-/ [ecmAO]: lacZpinAaberrant prestalk cell differentiation
DBS0350827 pinA-/ [pspA]: lacZpinAaberrant prespore cell differentiation
DBS0351429 pip5k3-/ AX2pip5k3decreased defense response to Gram-negative bacterium | aberrant defense response to bacterium | aberrant phagosome maturation | decreased protein processing in phagocytic vesicle | decreased protein localization to phagocytic vesicle
DBS0351428 pip5k3-/ AX3pip5k3aberrant macropinocytosis | decreased growth rate
SB16 pirA-pirAdecreased vegetative cell size | increased cell motility
SB3 pirA-pirAincreased actin filament polymerization | increased vegetative cell size | decreased cell motility | aberrant cellular response to stress | increased pseudopodium formation
DBS0351205 pirA-pirAdecreased cell motility | aberrant pseudopodium formation | abolished protein level
DBS0351533 pirA-/ AX2pirAdecreased protein level | aberrant macropinocytosis | aberrant cytokinesis | increased vegetative cell size | decreased cell motility | decreased pseudopodium formation | increased bleb assembly | decreased filopodium formation
DBS0351206 pirA-/ pirA(K193D/ R194D): EGFPpirAabolished protein localization to cell periphery | decreased protein phosphorylation
DBS0349901 pisA-pisAincreased gene expression | precocious development | decreased fruiting body size | aberrant prestalk cell differentiation
DBS0236783 pkaC-pkaCabolished gene expression | increased protein phosphorylation | aberrant response to abiotic stimulus | decreased protein level | decreased gene expression | decreased activation of GTPase activity | abolished catalytic activity | aberrant response to cAMP | increased cellular thermotolerance | aberrant myosin II filament organization | decreased protein kinase activation | abolished aggregation | aberrant actin filament organization | aberrant protein localization to plasma membrane | aberrant protein localization to cell cortex | abolished chemotaxis to cAMP | increased protein kinase activation | increased activation of GTPase activity | abolished positive regulation of chemorepellant activity
DBS0350694 pkaC-/ [act15]: pkaCpkaCabolished culmination
DBS0350708 pkaC-/ [act6]: pkaC(303-648)pkaCwild type
DBS0350707 pkaC-/ [act6]: pkaC(330-648)pkaCabolished aggregation
DBS0350710 pkaC-/ [dscC]: LUCpkaCdecreased gene expression | increased macropinocytosis
DBS0235411 pkaR-pkaRabolished stream development | increased resistance to valproic acid | decreased spore germination | aberrant extracellular cAMP signaling pathway | aberrant response to lithium | increased gene expression | precocious sporulation | increased lateral pseudopodium formation | aberrant chemotaxis to cAMP | decreased cell motility | decreased fruiting body size | aberrant cell morphology
DBS0351315 pkbA-pkbAdecreased macropinocytosis
DBS0236784 pkbA-pkbAdecreased pinocytosis | decreased protein phosphorylation | aberrant macropinocytosis | decreased bleb assembly | abolished protein kinase activation | abolished protein localization | abolished protein localization to trailing edge | aberrant phagosome maturation | increased phagocytosis | decreased myosin II assembly
DBS0349876 pkbA-pkbAaberrant cellular response to extracellular stimulus | increased protein kinase activation
DBS0350113 pkbA-/ [act15]: GFP: rheb(Q64L)pkbA | rhebdecreased phagocytosis
DBS0350916 pkcA-pkcAdecreased cell-cell adhesion | decreased protein level | increased chemotaxis to cAMP | decreased gene expression | increased number of mound tips | increased actin filament polymerization | aberrant oscillatory cAMP signaling | decreased fruiting body size | abolished positive regulation of chemorepellant activity
DBS0350918 pkcA-pkcAaberrant aggregation | decreased catalytic activity | aberrant cytokinesis | aberrant sorocarp development
DBS0350919 pkcA-/ [act15]: pldBpkcA | pldBaberrant aggregation | decreased sporulation
DBS0350917 pkcA-/ [ecmA]: GFPpkcAaberrant prestalk gene expression
DBS0350475 pkd2-pkd2increased resistance to naringenin | decreased growth rate
DBS0350367 pkd2-pkd2aberrant cellular response to fluid shear stress | aberrant exocytosis
DBS0351540 pkd2-/ AX2pkd2aberrant calcium-mediated signaling
DBS0236786 pkgB-pkgBdecreased protein phosphorylation | development arrests at mound stage | abolished spore cell differentiation
DBS0350328 pkgB-pkgBaberrant sorocarp development
DBS0351316 pkgB-pkgBdecreased macropinocytosis
DBS0304638 pkgB-pkgBdecreased cell-substrate adhesion | development arrests at mound stage | decreased chemotaxis rate | decreased taxis | increased cell motility | increased bleb assembly
DBS0236787 pkgB-/ [act15]: pkbApkbA | pkgBwild type
DBS0236789 pkgB-/ [act15]: pkgB(K182M)pkgBdevelopment arrests at mound stage
DBS0350329 pkgB-/ [emcB]: lacZpkgBabolished prestalk gene expression
DBS0236790 pkgB-/ [gbfA]: pkbApkbA | pkgBwild type
DBS0236791 pkgB-/ [gbfA]: pkgBpkgBwild type
DBS0350319 pks17-pks17decreased fatty acid level | increased gene expression | delayed development | decreased fruiting body size
LAS44 pks2-pks2decreased socially cooperative development
LAS19 pks26-pks26aberrant socially cooperative development
DBS0238068 plaA-plaAaberrant chemotaxis to cAMP | abolished aggregation | abolished positive regulation of chemorepellant activity
DBS0238067 plaA-plaAabolished aggregation
DG1067 plbG-plbGdecreased stalk width | decreased stalk length
HAD236 plc-plcdecreased protein localization to plasma membrane | aberrant chemotaxis to cAMP | decreased protein localization to cytoplasm | decreased protein kinase activation | abolished aggregation
HD1.19 plc-plcaberrant negative chemotaxis
HD10 plc-plcaberrant cellular homeostasis | wild type | aberrant spore germination
DBS0267125 plc-/ [OE]: dagA(PH): GFP/ [OE]: plcdagA | plcincreased protein localization to plasma membrane | decreased chemotaxis to cAMP
DBS0350047 plc-/ [act15]: pten: GFPplc | ptenwild type | aberrant protein localization to cytoplasm
DBS0236796 pldB-pldBdecreased catalytic activity | precocious aggregation
DBS0236797 pldB-/ [act15]: pldB: GFPpldBabolished aggregation
DBS0350604 pldB-/ [unk]: GFPpldBincreased cell migration to prestalk region
DBS0350605 pldB-/ [unk]: lacZpldBincreased cell migration to prestalk region
DBS0236799 plip-plipdelayed aggregation
DBS0351187 plnA-plnAaberrant defense response to bacterium
DBS0350007 png-pngdelayed aggregation | decreased mound size | aberrant fruiting body morphogenesis
DBS0350492 png-/ [ecmAO]: lacZpngaberrant prestalk cell differentiation
DBS0350491 png-/ [ecmA]: lacZpngaberrant prestalk A cell differentiation
DBS0350493 png-/ [pspA]: lacZpngdecreased prespore cell differentiation
DBS0236820 ponA-ponAprecocious aggregation | decreased actin nucleation | aberrant sorocarp development | aberrant pseudopodium formation
DBS0236821 ponA-ponAprecocious aggregation | decreased actin nucleation | aberrant sorocarp development | aberrant pseudopodium formation
DG1057 potA-potAaberrant fruiting body morphogenesis
DBS0351064 poxA-poxAaberrant defense response to bacterium
DBS0236824 ppk1-ppk1decreased growth rate | decreased phagocytosis | decreased fruiting body size | delayed culmination | decreased sporulation
ASH01 ppk1-ppk1aberrant cellular homeostasis | decreased ATP level | decreased growth rate | aberrant spore germination | aberrant macromolecule biosynthesis | decreased fruiting body size | increased growth rate
DBS0351356 ppk1-/ [act15]: GFP: hsp48hsp48 | ppk1decreased protein level
DBS0236825 ppk1-/ [act15]: ppk1ppk1wild type
DBS0238099 ppp4C-ppp4cdevelopment arrests at mound stage | delayed development
DBS0238110 ppp4C-/ [act15]: smkAppp4c | smkAdevelopment arrests at mound stage | delayed development
DBS0238033 proC-proCincreased lateral pseudopodium formation | decreased chemotaxis rate | decreased establishment of cell polarity
DBS0238034 proC-/ [unk]: FLAG: proCproCwild type
DBS0266716 pscA-pscAwild type
DBS0266803 psenA-psenAaberrant culmination | decreased prespore cell differentiation
DBS0350302 psenA-psenAdecreased prespore cell differentiation | aberrant calcium-mediated signaling
DBS0350295 psenB-psenBdecreased phagocytosis | abolished catalytic activity
DBS0350303 psenB-psenBdecreased prespore cell differentiation | aberrant calcium-mediated signaling
DBS0351095 psenB-psenBaberrant response to chemical
HOK2 psiA-psiAabolished prespore cell division
DBS0351581 psiA-/ [ecmB]: lacZpsiAprecocious prestalk gene expression
DBS0351578 psiA-/ [rnrB]: lacZpsiAaberrant prespore gene expression
DBS0236021 psiM-psiMwild type
DBS0236022 psiM-psiMwild type
DBS0236828 pslA-pslAabolished sporulation | increased mound size | decreased sorus size | aberrant prestalk gene expression | increased stalk length | abolished stalk cell differentiation | abolished prespore gene expression
DBS0236829 psmC1-psmC1increased resistance to spectinomycin | aberrant standing slug morphology | abolished slug migration | increased vegetative cell size
HW70 pspB-pspBaberrant spore coat morphology | precocious spore germination
DBS0302352 psrA-psrAdecreased culmination | increased protein phosphorylation | decreased activation of GTPase activity | delayed prestalk gene expression | decreased cell motility | delayed development | increased protein kinase activation
DBS0351094 psrA-psrAaberrant response to chemical
DBS0302356 psrA-/ [act15]: FLAG: gskAgskA | psrAincreased protein kinase activation
DBS0302353 psrA-/ [act15]: ecmA: lacZpsrAaberrant prestalk gene expression
DBS0302354 psrA-/ [act15]: ecmB: lacZpsrAaberrant prestalk gene expression
DBS0302357 psrA-/ [act15]: gskA(K84M/ K85M)gskA | psrAdecreased culmination | decreased prespore gene expression | delayed development | increased protein kinase activation
DBS0302355 psrA-/ [act15]: psrApsrAwild type
DBS0350829 psrA-/ [unk]: FLAG: rasD(G12T)psrA | rasDincreased protein kinase activation
HM1289 pten-ptenaberrant cell motility | decreased lateral pseudopodium retraction | decreased cell motility | decreased macropinocytosis | abolished aggregation | decreased chemotaxis to cAMP
DBS0236830 pten-ptendecreased response to Gram-negative bacterium | decreased positive regulation of GTPase activity | decreased actin filament polymerization | decreased lateral pseudopodium retraction | abolished protein localization to plasma membrane | decreased growth rate | increased actin filament polymerization | decreased phagocytosis | decreased bleb assembly | decreased cell motility | increased protein localization to plasma membrane | decreased chemotaxis to cAMP | abolished aggregation | aberrant pseudopodium formation | increased pseudopodium formation | aberrant signal transduction | abolished positive regulation of chemorepellant activity
DBS0349884 pten-ptenaberrant cytokinesis | increased protein kinase activity | decreased chemotaxis to cAMP | decreased establishment of cell polarity
DBS0350660 pten-ptendecreased uropod retraction | decreased protein localization to cleavage furrow | decreased growth rate | aberrant cytokinesis | decreased protein localization to pseudopodium
DBS0350454 pten-/ [act15]: lpten: RFPlpten | ptenwild type
DBS0349890 pten-/ [act15]: pakA: GFPpakA | ptenaberrant cytokinesis
DBS0350754 pten-/ [act15]: pten(186-515): GFPptenaberrant sorocarp development | decreased chemotaxis to cAMP
DBS0350755 pten-/ [act15]: pten(C124S): GFPptenaberrant sorocarp development | decreased chemotaxis to cAMP
DBS0351587 pten-/ [act15]: pten(G129E)ptenincreased lateral pseudopodium formation | aberrant localization
DBS0236831 pten-/ [act15]: pten: GFPptenwild type
DBS0349900 pten-/ pakA-/ [act15]: pakA(T585E): GFPpakA | ptenaberrant cytokinesis | decreased chemotaxis to cAMP
DBS0349899 pten-/ pakA-/ [act15]: pakA: GFPpakA | ptenaberrant cytokinesis
DBS0236832 ptpA1-ptpA1-1 | ptpA1-2decreased prespore cell differentiation | precocious development | increased prestalk O cell differentiation
DBS0236833 ptpB-ptpBincreased migratory slug size
DBS0350675 ptpB-/ [act15]: 6xHis: erkAerkA | ptpBaberrant stream morphology
DBS0236835 pufA-pufAincreased protein kinase activity | aberrant fruiting body morphogenesis | increased protein level | precocious development
DBS0304391 pyk3-pyk3increased prespore gene expression | decreased prestalk gene expression | increased prespore cell differentiation | delayed culmination
DBS0350577 pyk3-pyk3decreased protein phosphorylation | decreased gene expression | aberrant protein localization to nucleus
DBS0350581 pyk3-pyk3decreased protein phosphorylation | decreased gene expression
DBS0304393 pyk3-/ [act15]: T7: pyk3pyk3wild type
DBS0236837 pyr56-pyr56increased resistance to 5-Fluoroorotic acid | abolished uracil biosynthetic process
DBS0236838 pyr56-pyr56increased resistance to 5-Fluoroorotic acid | abolished uracil biosynthetic process
DBS0351499 pzoA-pzoAaberrant cellular response to fluid shear stress | aberrant chemotaxis to cAMP
DBS0350017 qdpr-qdprdecreased spore germination | decreased growth rate | abolished catalytic activity | aberrant response to oxidative stress
DBS0350018 qdpr-/ [act15]: pahpah | qdprdecreased growth rate
DBS0236839 qkgA-qkgA-1 | qkgA-2increased mound size | delayed aggregation | aberrant vegetative growth | aberrant nucleus organization | increased growth rate | abolished negative chemotaxis
DBS0351552 qkgA-qkgA-1 | qkgA-2aberrant aggregation | decreased actin filament polymerization | aberrant cytokinesis | decreased cell motility | decreased chemotaxis to cAMP
DBS0350011 qkgA-/ [act15]: bzpN: GFPbzpN | qkgA-1 | qkgA-2abolished negative regulation of vegetative growth
DBS0351560 qtrt1-qtrt1aberrant response to stimulus
DBS0350263 rab7A-rab7Adecreased growth rate
DBS0236841 racB-racBdecreased actin filament polymerization | delayed aggregation | aberrant fruiting body morphogenesis | decreased chemotaxis rate | decreased myosin II assembly
DBS0236842 racC-racCdecreased protein localization to plasma membrane | decreased actin filament polymerization | aberrant cytokinesis | aberrant stream morphology | decreased chemotaxis rate | aberrant cell morphology | aberrant protein localization
DBS0350272 racC-racCaberrant cytokinesis | decreased growth rate | abolished positive regulation of chemorepellant activity
DBS0237191 racC-/ [act15]: CFP: racCracCincreased actin filament polymerization
DBS0235413 racE-racEabolished cytokinesis | aberrant cortical actin cytoskeleton organization | abolished protein localization to cell cortex
DBS0350271 racE-racEdecreased protein phosphorylation | increased lateral pseudopodium formation | aberrant cytokinesis | delayed aggregation | decreased growth rate | aberrant regulation of GTPase activity | aberrant protein localization to plasma membrane | decreased establishment of cell polarity | decreased chemotaxis to cAMP
DBS0351308 racE-racEaberrant cortical actin cytoskeleton organization | abolished protein localization to cell cortex | aberrant cytokinesis | decreased cell motility | aberrant cell morphology
DBS0351348 racE-/ [act15]: GFP: racE(G20V)racEdecreased protein phosphorylation | decreased chemotaxis to cAMP
DBS0351349 racE-/ [act15]: GFP: racE(G23V)racEincreased protein phosphorylation
DBS0351350 racE-/ [act15]: GFP: racE(S192D)racEincreased protein phosphorylation | wild type
DBS0351347 racE-/ [act15]: GFP: racE(T25N)racEwild type
DBS0351614 racE-/ [act15]: GFP: racE(T25N/ S192D)racEwild type
DBS0351351 racE-/ [act15]: GFP: rasC(Q62L)racE | rasCdecreased protein phosphorylation
DBS0349949 racE-/ [act15]: fttBfttB | racEdecreased growth rate
DBS0349946 racE-/ [act15]: fttB: GFPfttB | racEabolished protein localization to cell cortex
DBS0350956 racE-/ [act15]racE(G20V)racEwild type
DBS0350957 racE-/ [act15]racE(T25N)racEabolished cytokinesis
DBS0351505 racF1-racF1wild type
DBS0236843 racF2-racF2increased mound size | increased cell-cell adhesion | decreased sexual fusion
DBS0236849 racG-racGdecreased cell motility | decreased protein localization to phagocytic vesicle
DBS0236850 racH-racHdecreased exocytosis | aberrant protein localization to cytoplasmic vesicle | decreased pinocytosis | decreased defense response to Gram-negative bacterium | aberrant defense response to bacterium | decreased defense response to bacterium
DBS0351149 rapC-rapCincreased number of mound tips | aberrant cytokinesis | increased cell-substrate adhesion | decreased cell motility | aberrant cell morphology
DBS0266936 rapgap1-rapgap1decreased positive regulation of GTPase activity | increased actin filament polymerization | increased cell-substrate adhesion | decreased cell motility | decreased myosin II assembly | increased protein kinase activation
DBS0266937 rapgap1-/ [act15]: GFP: rapgap1rapgap1increased positive regulation of GTPase activity | increased lateral pseudopodium formation | decreased cell-substrate adhesion | increased myosin II assembly | increased actin filament polymerization | increased cell motility
DBS0351487 rapgap3-rapgap3increased cell motility | increased activation of GTPase activity
DBS0350864 rapgap3-/ AX2rapgap3delayed aggregation | decreased chemotaxis to cAMP | decreased fruiting body size
DBS0350863 rapgap3-/ KAX3rapgap3delayed development of tipped mound | increased calcium-dependent cell-cell adhesion | decreased cell motility | aberrant cell migration to prestalk region | aberrant regulation of GTPase activity
DBS0350316 rapgap9-rapgap9increased filopodium formation | increased actin filament polymerization | aberrant cytokinesis | decreased spore size | increased cell-substrate adhesion | decreased chemotaxis to cAMP
DBS0350317 rapgap9-/ [act15]: GFP: rapgap9rapgap9wild type
DBS0350628 rapgapB-rapgapBaberrant aggregation | increased cell-substrate adhesion | aberrant regulation of GTPase activity | aberrant actin filament organization
DBS0350630 rapgapB-/ [ecmAO]: RFPecmA | rapgapBaberrant cell-cell adhesion
DBS0350631 rapgapB-/ [ecmA]: lacZrapgapBaberrant cell migration to prestalk region
DBS0350632 rapgapB-/ [ecmO]: lacZrapgapBaberrant cell migration to prestalk region
DBS0350629 rapgapB-/ [pspA]: RFPpspA | rapgapBaberrant cell-cell adhesion
DBS0236852 rasB-rasBdecreased growth rate
DBS0350836 rasB-rasBdecreased phagocytosis | decreased macropinocytosis | aberrant actin filament organization
DBS0236853 rasC-/ AX2rasCincreased rate of endocytosis | aberrant response to cAMP | decreased cell motility | increased vegetative cell size | abolished protein kinase activation | decreased protein kinase activation | decreased taxis | abolished aggregation | aberrant pseudopodium formation | aberrant actin filament organization | aberrant protein localization to cell cortex | aberrant cellular response to extracellular stimulus
DBS0236854 rasC-/ JH10rasCwild type | aberrant gene expression | decreased protein kinase activation | abolished aggregation | abolished chemotaxis to cAMP
DBS0237614 rasC-/ [act15]: gbpDgbpD | rasCincreased cell-substrate adhesion | aberrant cell morphology
DBS0350740 rasC-/ [rasC]: rasGrasC | rasGabolished activation of adenylate cyclase activity | abolished aggregation
DBS0350742 rasC-/ [rasC]: rasG(1-77(D30A)): rasC(79-189)rasC | rasGwild type
DBS0350741 rasC-/ [rasC]: rasG(D30A)rasC | rasGaberrant aggregation | decreased activation of adenylate cyclase activity
DBS0351213 rasC-[act15]: rasG(S17N)rasC | rasGabolished activation of GTPase activity | decreased chemotaxis to cAMP
DBS0236860 rasD-rasDaberrant thermotaxis | aberrant phototaxis
DBS0351459 rasD-/ AX3rasDincreased gene expression | increased prespore cell differentiation
DBS0236862 rasG-/ AX2rasGdecreased pinocytosis | decreased gene expression | delayed aggregation | aberrant taxis | decreased cGMP-mediated signaling | decreased protein kinase activation | delayed gene expression
IR15 rasG-/ AX2rasGaberrant cell separation during cytokinesis | aberrant filopodium formation | decreased actin filament polymerization | decreased growth rate | increased vegetative cell size | decreased macropinocytosis | decreased cell motility | decreased protein kinase activation | decreased establishment of cell polarity | aberrant actin filament organization
IR17 rasG-/ AX3rasGaberrant cytokinesis | decreased cell motility | increased vegetative cell size
DBS0351460 rasG-/ AX3rasGincreased prestalk cell differentiation
DBS0236863 rasG-/ JH10rasGaberrant cell separation during cytokinesis | wild type | decreased gene expression | delayed aggregation | abolished activation of GTPase activity | aberrant chemotaxis to folate | decreased growth rate | decreased cGMP-mediated signaling | decreased protein kinase activation | delayed gene expression
DBS0236864 rasG-/ [OE]: rasBrasB | rasGdecreased growth rate
DBS0350572 rasG-/ [act15]: FLAG: rasG(K169R,K173R,K176R,K178R)rasGaberrant cytokinesis
DBS0350571 rasG-/ [act15]: FLAG: rasG(K169R,K173R,K176R,K178R,K179R,K180R,K184R)rasGdecreased protein modification
DBS0350448 rasG-/ [dscB]: rasG(S17N)rasGdecreased positive regulation of GTPase activity | decreased actin filament polymerization | decreased protein kinase activation | decreased chemotaxis to cAMP
DBS0236872 rasS-/ AX2rasSdecreased macropinocytosis | decreased cell motility | aberrant pinosome maturation | decreased establishment of cell polarity
DBS0351446 rasS-/ AX2rasSaberrant macropinocytosis
DBS0236873 rasS-/ DH1rasSdecreased rate of endocytosis | decreased growth rate | increased actin filament polymerization | abolished vegetative growth | increased cell motility | aberrant cytoskeleton organization
DBS0351314 rasS-/ DdBrasSdecreased macropinocytosis | increased cell motility
DBS0236874 rasZ-rasZwild type
DBS0351598 rbdB-rbdBabolished pre-miRNA processing
DBS0350261 rbg3-rbg3precocious development | increased growth rate
DBS0236877 rblA-rblAincreased cell migration to prestalk region | decreased spore germination | decreased gene expression | increased gene expression | abolished negative regulation of vegetative growth | decreased growth rate | aberrant vegetative growth | decreased vegetative cell size | precocious development | increased prestalk cell differentiation
DBS0349999 rblA-/ [act15]: GFPrblAincreased cell migration to prestalk region
DBS0349996 rblA-/ [act15]: GFP/ [act15]: myc: btgbtg | rblAincreased cell migration to prestalk region
DBS0236878 rbrA-rbrAincreased gene expression | decreased gene expression | development arrests at slug stage | aberrant prespore gene expression | decreased cell migration to prestalk region | decreased phototaxis | decreased sporulation
DBS0236879 rbrA-/ [unk]: rbrArbrAwild type
DBS0305613 rccA-rccAincreased resistance to cheating during development
DBS0236880 rckA-rckAincreased mound size | precocious aggregation | delayed slug development | delayed prestalk gene expression | delayed prespore gene expression | increased chemotaxis rate
DBS0236885 rckA-/ [act15]: myc: rckArckAdelayed development | decreased chemotaxis rate
DBS0236881 rckA-/ [act15]: myc: rckA(C551A)rckAdelayed slug development | decreased chemotaxis rate
DBS0236882 rckA-/ [act15]: myc: rckA(E510G)rckAwild type | decreased chemotaxis rate
DBS0236883 rckA-/ [act15]: myc: rckA(E510G/ N511A)rckAdelayed slug development | decreased chemotaxis rate
DBS0236884 rckA-/ [act15]: myc: rckA(K867A)rckAdevelopment arrests at mound stage | decreased chemotaxis rate
FR17 rdeA-rdeAprecocious aggregation | decreased mound size | aberrant fruiting body morphogenesis | precocious development | precocious gene expression
WTC10 rdeA-rdeAaberrant chemotaxis to cAMP | increased cAMP level | decreased macropinocytosis
FR17 rdeA-rdeAprecocious aggregation | decreased mound size | aberrant fruiting body morphogenesis | precocious development | precocious gene expression
DBS0236886 rdeA-/ [act15]: rdeArdeAwild type
DBS0350468 rdiA-rdiAdecreased pinocytosis | decreased protein localization to cell cortex | decreased protein level | decreased actin filament polymerization | aberrant contractile vacuole morphology | decreased growth rate | aberrant cytokinesis
DBS0351504 rdiA-rdiAaberrant cytokinesis
DBS0236887 recA-recAdecreased resistance to hydrogen peroxide | aberrant response to UV | decreased resistance to mitomycin C
DBS0266664 redA-redAdevelopment arrests at mound stage | aberrant mound color
DBS0350511 redA-redAdecreased defense response to Gram-negative bacterium
DG1047 redA-redAdevelopment arrests at mound stage | aberrant mound color
DBS0236889 regA-regAincreased resistance to cisplatin | aberrant chemotaxis to cAMP | increased cAMP level | aberrant fruiting body morphogenesis
DBS0236958 regA-regAdecreased spore germination | precocious sporulation | abolished protein localization to cell cortex | increased lateral pseudopodium formation | aberrant chemotaxis to cAMP
HM332 regA-regAdecreased lateral pseudopodium retraction
HR45 regA-regAaberrant fruiting body morphogenesis
HM1015 regA-regAincreased cAMP level | decreased macropinocytosis | aberrant oscillatory cAMP signaling
DBS0350372 regA-/ KAX3regAprecocious sporulation | increased sporulation
DBS0235706 regA-/ [act15]: dhkK(D1125N)dhkK | regAaberrant fruiting body morphogenesis | precocious development
DBS0235708 regA-/ [act15]: dhkK(H825Q)dhkK | regAaberrant fruiting body morphogenesis | precocious development
DBS0351475 regA-/ [act15]: erkAerkA | regAdelayed slug development
DBS0351472 regA-/ [act15]: regA(R588A,R589A,L594A,I595A,L596A)regAdelayed development
DBS0351284 regA-/ [act15]: regA(S142A)regAaberrant fruiting body morphogenesis | precocious development
DBS0351283 regA-/ [act15]: regA(S142E)regAdelayed development
DBS0351285 regA-/ [act15]: regA(S413A)regAincreased mound size | delayed development
DBS0351286 regA-/ [act15]: regA(S413E)regAincreased mound size | delayed development
DBS0351287 regA-/ [act15]: regA(T676A)regAdelayed sporulation
DBS0351288 regA-/ [act15]: regA(T676E)regAaberrant fruiting body morphogenesis | precocious development
DBS0350689 regA-/ [regA]: regAregAwild type
DBS0350670 regA-/ [regA]: regA(D212N)regAprecocious sporulation
DBS0351473 regA-/ regA(R588A,R589A,L594A,I595A,L596)regAprecocious sporulation | decreased mound size | increased protein binding | aberrant fruiting body morphogenesis
HM1351 rev3-rev3aberrant vegetative growth | decreased resistance to cisplatin
HM1451 rev3-/ xpf-rev3 | xpfdecreased resistance to cisplatin
DBS0236893 rgaA-rgaAabolished cell migration to prestalk region | aberrant cytokinesis | abolished stalk cell differentiation | decreased protein kinase activation | abolished culmination | decreased sporulation
DBS0349935 rgaA-rgaAaberrant stalk morphogenesis | increased number of tip-organizers | aberrant cellular response to fluid shear stress | increased actin filament polymerization | increased growth rate | increased cell motility | aberrant actin filament organization
DBS0350398 rgaA-rgaAincreased lateral pseudopodium formation | decreased myosin II assembly | increased chemotaxis rate
DBS0349921 rgaA-/ [act15]: GFP-mhcArgaAaberrant stalk morphogenesis | aberrant development of tipped mound | abolished protein localization to apical plasma membrane
DBS0351526 rgbA-/ AX2rgbAaberrant macropinocytosis | aberrant activation of GTPase activity | decreased macropinocytosis | aberrant engulfment during phagocytosis | decreased chemotaxis to folate
DBS0351527 rgbA-/ DdBrgbAaberrant macropinocytosis | increased activation of GTPase activity
DBS0350019 rgfA-rgfAwild type
DBS0350020 rgfA-/ [act15]: rgfArgfAdecreased chemotaxis to folate | delayed development
DBS0350108 rheb-rhebincreased phagocytosis
DBS0236894 rhgA-rhgAwild type
DBS0350192 ric8-ric8abolished gene expression | abolished chemotaxis to folate | decreased chemotaxis to cAMP | abolished aggregation | aberrant signal transduction
DBS0350193 ric8-/ [act15]: GFP: ric8ric8wild type
DBS0236900 ripA-ripAdecreased guanylyl cyclase activity | abolished activation of adenylate cyclase activity | decreased chemotaxis rate | decreased taxis | abolished aggregation | decreased establishment of cell polarity | aberrant regulation of protein kinase activity | decreased myosin II assembly | increased phagocytosis
DBS0350770 ripA-/ [act15]: GFP: rapA(G12V)rapA | ripAdecreased protein kinase activation
DBS0350115 ripA-/ [act15]: GFP: rheb(Q64L)rheb | ripAincreased phagocytosis
DBS0236902 ripA-/ [unk]: ripA(K680E/ R681E)ripAaberrant sorocarp development | decreased chemotaxis rate
DBS0236901 ripA-/ [unk]ripAripAwild type
DBS0351068 rnf113-rnf113delayed aggregation | increased cell-substrate adhesion | decreased cell motility
DBS0351042 rnlA-rnlAdecreased thermotaxis | decreased growth rate | decreased defense response to bacterium | decreased phototaxis
DBS0236903 rnpA-rnpAincreased gene expression
DBS0350096 roco11-roco11increased stalk length
DBS0350095 roco4-roco4delayed slug development | aberrant stalk development | delayed culmination
DBS0350100 roco4-/ [unk]: roco4(1018-1292(G1179S))roco4increased catalytic activity
DBS0350098 roco4-/ [unk]: roco4(1018-1292(S1187A))roco4abolished catalytic activity
DBS0350099 roco4-/ [unk]: roco4(1018-1292(S1189A))roco4decreased catalytic activity
DBS0238225 rpkA-rpkAdevelopment arrests at loose mound stage | decreased defense response to Gram-negative bacterium | aberrant cellular response to nitrogen starvation | decreased phagocytosis | decreased cell motility | decreased establishment of cell polarity | abolished aggregation | aberrant cellular response to extracellular stimulus
DBS0236906 rrpA-rrpAabolished post-transciptional gene silencing by RNA
DBS0350209 rrpC-rrpCdecreased gene expression | increased gene expression
DBS0350219 rrpC-/ [act15]: pre-miRNArrpCincreased pre-miRNA processing
DBS0350216 rrpC-/ [act6]: LacZ/ [RNAi]lacZrrpCabolished transitive RNA interference
DBS0350217 rrpC-/ [act6]: lacZ/ [AS]lacZrrpCaberrant production of siRNA involved in RNA interference
DBS0236875 rtoA-rtoAdecreased rate of endocytosis | increased defense response to Gram-negative bacterium | increased prestalk cell differentiation | delayed culmination
DBS0236911 rtoA-rtoAdelayed development
DBS0236914 rzpA-rzpAaberrant aggregation | decreased slug migration | increased mound size | increased prespore gene expression | decreased prestalk gene expression | delayed development
DBS0309040 sadA-sadAabolished protein localization to cell surface | decreased phagocytosis | decreased protein stabilization
DBS0236921 sadA-sadAabolished cell-substrate adhesion | decreased phagocytosis | aberrant cytokinesis | increased growth rate | aberrant actin filament organization | aberrant cell morphology
DBS0350974 sadA-/ [act15]: gpaHgpaH | sadAaberrant cytokinesis
DBS0349790 sadA-/ [act15]: sadA(1-923): GFPsadAdecreased cell-substrate adhesion
DBS0349792 sadA-/ [act15]: sadA(S924A/ S925A): GFPsadAwild type
DBS0349791 sadA-/ [act15]: sadA(S924E/ S925E): GFPsadAdecreased cell-substrate adhesion
DBS0236922 sadA-/ [act15]: sadA: GFPsadAwild type
DG1105 scaA-scaAabolished aggregation
DBS0350825 scaA-scaAdecreased actin filament polymerization | aberrant chemotaxis to cAMP | abolished activation of GTPase activity | decreased protein kinase activation | abolished aggregation
DBS0236924 scrA-scrAincreased number of tip-organizers | abolished protein localization to endolysosome | decreased exocytosis | decreased pinocytosis | decreased actin filament polymerization | increased lateral pseudopodium formation | decreased phagocytosis | decreased vegetative cell size | decreased fruiting body size | precocious development
IR46 scrA-scrAaberrant mitotic spindle organization | aberrant cytokinesis | abolished activation of GTPase activity | decreased vegetative cell size | decreased cell motility | aberrant cellular response to stress | aberrant pseudopodium formation | increased bleb assembly | abolished positive regulation of chemorepellant activity
IR48 scrA-scrAdecreased growth rate | aberrant cytokinesis | decreased bleb assembly | decreased phototaxis
DBS0236925 scrA-scrAincreased filopodium formation | decreased protein level | aberrant macropinocytosis | aberrant cytokinesis | decreased macropinocytosis | decreased cell motility | aberrant actin filament organization | aberrant pseudopodium formation
DBS0351524 scrA-/ [act15]: scrA(R177A,R179A,K180A,R183A,R184A,R187A,K190A,K191A,K194A)scrAdecreased bleb assembly | increased cellular localization | aberrant pseudopodium formation
DBS0351611 scrA-/ [act15]: scrA(S287,290,301,335,339,384,388,389,430,432,433,437,440A)scrAaberrant pseudopodium formation
DBS0351522 scrA-/ [act15]: scrA(S430A,S432A,S433A,S437A,S440A)scrAdecreased bleb assembly | increased cellular localization | aberrant pseudopodium formation
DBS0351523 scrA-/ [act15]: scrA(S430D,S432D,S433D,S437D,S440D)scrAdecreased pseudopodium size
DBS0349927 scrA-/ [act15]: wasA: GFP/ [ act8]: RFP: arcDscrAdecreased establishment of cell polarity | decreased pseudopodium formation
DBS0350063 scrA-/ [tet]: scrA/ mhcA-mhcA | scrAaberrant cytokinesis
DBS0351610 scrA-/ [tet]: scrA/ wasA-scrA | wasAaberrant cell motility | abolished vegetative growth | abolished bleb assembly | aberrant pseudopodium formation
DBS0238440 scrA-/ [unk]: scrA(97-443): GFPscrAaberrant cytokinesis | increased vegetative cell size | decreased chemotaxis to cAMP | aberrant cytoskeleton organization
DBS0238446 scrA-/ [unk]: scrA: GFPscrAwild type
HM1163 sec1-/ sec1(M213K/ E258G/ M427V/ K527I/ T541N/ F558S/ N581D)sec1abolished cell motility
HM1325 sec1-/ sec1(M250L/ A296V/ M427L/ S435R/ K505N/ V552D/ H570Q)sec1abolished cytokinesis | aberrant hypotonic response | abolished cell motility | aberrant plasma membrane organization | aberrant cell morphology
DBS0350286 sec1-/ sec1(M250L/ A296V/ M427L/ S435R/ K505N/ V552D/ H570Q)/ gppA: GFPgppA | sec1abolished contractile vacuole discharge
DBS0350101 sec7-sec7aberrant cell motility | decreased phagocytosis | decreased growth rate | aberrant phototaxis | decreased protein secretion
DBS0306234 secG-secGdecreased cell-substrate adhesion | decreased chemotaxis rate
DBS0351035 seiP-seiPaberrant lipid droplet formation
DBS0350264 sepA-sepAaberrant cytokinesis | delayed aggregation | decreased growth rate | decreased fruiting body size
DBS0351077 sepA-sepAaberrant gene expression | increased cell-substrate adhesion | decreased cell motility
DBS0350906 sepA-sepAdecreased protein phosphorylation | aberrant pseudopodium formation
DBS0351252 sesn-sesnincreased mound size | aberrant standing slug morphology | decreased gene expression | decreased autophagy | aberrant response to oxidative stress
DBS0236928 set1-set1precocious aggregation | abolished histone H3-K4 methylation | precocious gene expression
DG1008 sfbA-sfbAdecreased fruiting body size
DBS0350889 sgcA-/ AX2sgcAaberrant aggregation | decreased guanylyl cyclase activity | aberrant chemotaxis to cAMP
DBS0350888 sgcA-/ AX3sgcAaberrant aggregation | decreased guanylyl cyclase activity | aberrant chemotaxis to cAMP
SA576 sgkA-sgkAdecreased resistance to carboplatin | decreased growth rate | decreased resistance to cisplatin
HM1091 sgkB-sgkBdecreased resistance to carboplatin | decreased growth rate | decreased resistance to cisplatin
SA555 sglA-sglAincreased stalk width | increased resistance to cisplatin | increased mound size | decreased lateral pseudopodium retraction | decreased gene expression | abolished slug migration | decreased cell motility | decreased chemotaxis rate | decreased fruiting body size | aberrant cytoskeleton organization | decreased sporulation | increased resistance to carboplatin
SA554 sglA-sglAdelayed aggregation | decreased mound size
DBS0236934 shkA-shkAaberrant aggregation | decreased phagocytosis | aberrant cytokinesis | decreased chemotaxis rate | decreased fruiting body size | decreased establishment of cell polarity | aberrant actin filament organization
DBS0236935 sibA-sibAdecreased cell-substrate adhesion | decreased phagocytosis
DBS0302653 sibC-sibCdecreased phagocytosis
DBS0236936 sigB-sigBwild type
DBS0236937 sigD-sigDwild type
DBS0351170 sir2A-sir2Aabolished slug migration | increased number of mound tips | increased gene expression | decreased gene expression | decreased growth rate | aberrant sorocarp development | decreased autophagy | decreased chemotaxis to cAMP | decreased cAMP level
DBS0350859 sir2D-sir2Ddecreased gene expression | increased gene expression | increased number of mound tips | delayed aggregation | decreased growth rate | decreased autophagy | decreased mound size | decreased stalk length
DBS0350860 sir2D-/ [ecmAO]: lacZsir2Ddecreased prestalk cell differentiation
DBS0350861 sir2D-/ [pspA]: lacZsir2Daberrant prespore cell differentiation
DBS0350985 slc4-slc4aberrant transport
DBS0349958 sma-smaincreased chemotaxis to folate | decreased gene expression | increased cell-substrate adhesion | decreased vegetative cell size | increased cell-cell adhesion
DBS0349957 sma-/ ampA/ [ampA]: ampAampA | smadecreased chemotaxis to folate
DBS0350327 smdA-/ [pspA]: lacZsmdAaberrant gene expression
DBS0236938 smkA-smkAaberrant cytokinesis | delayed development | decreased chemotaxis rate | decreased myosin II assembly
HDB7YA smlA-smlAincreased oscillatory cAMP signaling | decreased cell-cell adhesion | aberrant cellular metabolic process | decreased response to Gram-negative bacterium | increased resistance to cisplatin | decreased protein level | decreased guanylyl cyclase activity | increased myosin II assembly | increased actin filament polymerization | decreased cGMP-mediated signaling | decreased mound size | increased protein level | decreased secretion of lysosomal enzymes | increased cell motility | decreased fruiting body size
DBS0304496 smlA-/ sslA1(CR11)smlA | sslA1increased fruiting body size
DBS0350977 snfA-snfAdecreased pinocytosis | increased cell death | decreased autophagic cell death | decreased phagocytosis | decreased number of autophagosomes | aberrant sorocarp development | decreased prespore cell differentiation | aberrant gene expression | aberrant protein modification | increased growth rate | aberrant prestalk cell differentiation | aberrant sporulation
DBS0302523 sodC-sodCaberrant cytokinesis
DBS0302524 sodC-sodCaberrant aggregation | decreased positive regulation of GTPase activity | decreased actin filament polymerization | increased actin filament polymerization | aberrant chemotaxis to cAMP | increased protein localization to plasma membrane | decreased chemotaxis rate | aberrant regulation of GTPase activity | aberrant protein localization to plasma membrane | aberrant cell morphology | increased protein kinase activation
DBS0351063 sodC-/ [unk]: rasG(C118A)rasG | sodCaberrant regulation of GTPase activity
DBS0350894 sodD-sodDaberrant response to UV
DBS0351196 sogA-sogAaberrant chemotaxis to cAMP | increased activation of GTPase activity
DBS0350966 spaA-spaAabolished sporulation
AK1346 spc3-spc3decreased response to Gram-negative bacterium
DBS0350891 spdA-spdAdecreased substrate adhesion-dependent cell spreading | decreased phagocytosis
HL351 spiA-spiAdecreased spore germination
DBS0236945 splA-splAabolished sporulation | aberrant spore morphology | increased sorus size | aberrant sorus color | decreased stalk length
DBS0350131 splB-splBabolished protein tyrosine phosphorylation | abolished protein localization to nucleus | abolished response to DIF-1 | decreased gene expression
DBS0236947 spnA-spnAabolished prespore cell differentiation | development arrests at mound stage | abolished prestalk cell differentiation | aberrant sorocarp development
DBS0236949 spr-sprdecreased spore germination | decreased pteridine level | decreased cytochrome C oxidase activity | decreased growth rate
DBS0350914 spsA-spsAdecreased stalk length
DBS0351174 srcp1-srcp1aberrant protein modification
DBS0236950 srfA(1-8): lacZsrfAdecreased slug migration | aberrant fruiting body morphogenesis | delayed culmination
DBS0236951 srfA-srfAaberrant spore morphology | decreased spore germination | aberrant spore coat morphology | decreased gene expression
DBS0266691 srfB-srfBabolished stream development | aberrant extracellular cAMP signaling pathway | increased lateral pseudopodium formation | precocious aggregation | decreased growth rate | increased pinocytosis | aberrant cytokinesis | precocious gene expression
DBS0304409 srsA-srsAincreased mound size | decreased gene expression | increased gene expression | delayed aggregation
DBS0236952 stkA-stkAdecreased gene expression | increased prestalk gene expression | delayed prespore gene expression | aberrant fruiting body morphogenesis | increased prestalk cell differentiation
HM1157 stlA-stlAaberrant aggregation | abolished sporulation | wild type | increased gene expression | decreased gene expression | aberrant stream morphology | decreased spore cell differentiation | decreased chemotaxis to cAMP | aberrant sorus color | abolished MPBD level | decreased cAMP level | aberrant sporulation
DBS0350222 stlA-/ [cotB]: lacZstlAdecreased sporulation | aberrant prespore cell differentiation
HM1154 stlB-stlBabolished DIF-1 biosynthesis | abolished prestalk B cell differentiation | aberrant gene expression | aberrant fruiting body morphogenesis | decreased prestalk O cell differentiation | abolished lower cup formation | abolished outer basal disc formation | decreased prestalk cell differentiation
DBS0351220 stlB-stlBabolished autophagosome organization | abolished autophagic cell death
DBS0350409 stlB-/ [act15]: stlBstlBwild type
DBS0304547 svkA-svkAdelayed cell separation during cytokinesis | aberrant cytokinesis | aberrant fruiting body morphogenesis
DBS0236055 swip-swipaberrant protein localization to cytoplasm | abolished exocytosis | abolished phagosome reneutralization | abolished actin filament polymerization | aberrant protein localization
AK1321 swp1-swp1decreased response to Gram-positive bacterium
AK1200 tagA-tagAdecreased spore cell differentiation | aberrant fruiting body morphogenesis
AK859 tagA-tagAdecreased spore germination | increased number of mound tips | decreased spore cell differentiation | increased prestalk A cell differentiation | delayed culmination | decreased sporulation
AK1201 tagA-/ [ecmA]: GFPtagAabolished cell migration to prestalk region
AK228 tagB-tagBabolished sporulation | abolished DIF-1 biosynthesis | development arrests at mound stage | aberrant prestalk A cell differentiation
DBS0350637 tagB-/ [pkaC]: pkaCpkaC | tagBaberrant response to biotic stimulus | abolished spore cell differentiation
DBS0236975 tagC-tagCabolished sporulation | development arrests at mound stage
DBS0350698 tagC-/ [pkaC]: pkaCpkaC | tagCdevelopment arrests at mound stage | abolished spore cell differentiation
DBS0236976 talA-talAdecreased protein level | decreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | aberrant cell morphology
HG1666 talA-talAdecreased cell-cell adhesion | decreased cell-substrate adhesion | aberrant cytokinesis | decreased growth rate | decreased phagocytosis | increased cell-substrate adhesion
HG1663 talA-talAdecreased cell-substrate adhesion
HG1664 talA-talAdecreased uropod retraction | decreased growth rate | decreased phagocytosis | aberrant mitotic actomyosin contractile ring contraction
HG1665 talA-talAdecreased cell-cell adhesion | aberrant cytokinesis
DBS0304585 talA-/ [act15]: FLAG: talBtalA | talBdecreased cell-substrate adhesion
DBS0237616 talA-/ [act15]: gbpDgbpD | talAincreased cell-substrate adhesion | aberrant cell morphology | increased pseudopodium formation
DBS0238395 talA-/ [act15]: rapA(G12V)rapA | talAincreased cell-substrate adhesion
DBS0304582 talA-/ talB-/ [act15]: FLAG: talBtalA | talBwild type
HKT104 talB-talBdecreased slug migration | aberrant extracellular cAMP signaling pathway | aberrant cellular process | decreased cell motility | development arrests at tipped mound stage | increased protein level | aberrant signal transduction
DBS0302472 talB-talBabolished autophagosome organization | abolished autophagic cell death | aberrant autophagic cell death
DBS0304586 talB-/ [act15]: talA: GFPtalA | talBaberrant fruiting body morphogenesis
DBS0350712 talB-/ [act15]: talB(K16A)talBdevelopment arrests at tipped mound stage
DBS0351346 tert-tertincreased gene expression | decreased gene expression | aberrant cell adhesion | aberrant chemotaxis to cAMP | aberrant sorocarp development | delayed development | aberrant oscillatory cAMP signaling | decreased cAMP level
DBS0351559 tert-tertdecreased catalytic activity | increased gene expression
AK1505 tgrB1-tgrB1development arrests at loose mound stage | delayed sporulation | decreased cell motility | decreased sporulation
AK127 tgrC1-tgrC1development arrests at loose mound stage | aberrant aggregation | abolished gene expression | increased mound size | decreased gene expression
AK1521 tgrC1-tgrC1abolished sporulation | development arrests at loose mound stage | decreased cell motility
AK1657 tgrC1-/ (QS38|tgrC1)/ alg9(-19ins)alg9 | tgrC1delayed development | decreased fruiting body size | decreased sporulation
AK1661 tgrC1-/ alg9(-19ins)alg9 | tgrC1delayed development | decreased fruiting body size | decreased sporulation
DBS0350743 tgrC1-/ alg9(-19ins)-REMIalg9 | tgrC1decreased sporulation
DBS0350625 tgrC1-/ stcA-stcA | tgrC1decreased mound size | delayed development | decreased sporulation
DBS0350626 tgrC1-/ stcB-stcB | tgrC1decreased mound size | delayed development | decreased sporulation
DBS0350627 tgrC1-/ stcC-stcC | tgrC1aberrant stream morphology | delayed development | decreased fruiting body size | decreased sporulation
AK244 tipA-tipAincreased number of tip-organizers | increased mound size | development arrests at mound stage | decreased prestalk gene expression
DBS0351500 tipB-tipBincreased number of mound tips
JS56 tipB-tipBincreased number of tip-organizers | increased mound size | increased number of mound tips | development arrests at mound stage
JS55 tipC-tipCincreased number of tip-organizers | increased mound size | development arrests at mound stage | decreased number of autophagosomes | decreased autophagy
DBS0350729 tipC-/ [unk]: tipC(2725-3848): GFPtipCdecreased fruiting body size
JS93 tipD-tipDincreased number of tip-organizers | increased mound size | development arrests at mound stage | aberrant vacuole organization | decreased autophagy
DBS0350730 tipD-tipDdecreased pinocytosis | increased cell death | decreased spore germination | decreased catalytic activity | increased gene expression | increased number of mound tips | increased protein modification | aberrant phagosome maturation | aberrant slug development | aberrant fruiting body morphogenesis | abolished protein localization to autophagosome
DBS0304519 tirA-tirAdecreased response to Gram-negative bacterium | decreased defense response to Gram-negative bacterium | aberrant defense response to bacterium | decreased growth rate | aberrant phagocytosis | aberrant vegetative growth
YLD31A tlp2-tlp2decreased growth rate
DBS0236016 tmcB-/ V12tmcBdecreased macrocyst size | aberrant macrocyst formation
DBS0236018 tmcC-/ V12tmcCaberrant macrocyst formation
DBS0350285 tom1-tom1decreased rate of endocytosis
DBS0237017 torA-torAdelayed aggregation | decreased growth rate | decreased cell motility | decreased chemotaxis rate
DBS0237018 torA-/ [act15]: torA: GFPtorAabolished vegetative growth
DBS0351498 tpc2-tpc2increased number of autophagosomes | increased gene expression | decreased gene expression | aberrant vegetative growth | aberrant calcium-mediated signaling | increased protein kinase activity | delayed development | increased lysosomal pH
DBS0350506 tpp1-tpp1aberrant response to chemical
DBS0350504 tpp1-tpp1increased autophagic cell death | decreased catalytic activity | aberrant response to chemical | aberrant cell morphology | precocious development | decreased sporulation
DBS0350505 tpp1-/ [cotB]: tpp1tpp1wild type
DBS0351017 tpp1F-tpp1Fwild type
DBS0351558 tpt1-tpt1decreased spore germination | decreased gene expression | decreased growth rate | aberrant cytokinesis | decreased number of mounds | decreased macropinocytosis | delayed development | aberrant fruiting body morphogenesis | increased prestalk cell differentiation
DBS0351265 trfA-trfAaberrant aggregation | aberrant vegetative growth | decreased chemotaxis to cAMP
DBS0237924 triA-triAdecreased cell-cell adhesion | increased stalk width | increased number of mounds | decreased spore germination | aberrant upper cup formation | aberrant cell motility | aberrant stream morphology | decreased spore size | decreased cell fate determination | aberrant late culminant morphology
DBS0237996 triA-triAaberrant late culminant morphology
DBS0237997 triA-triAaberrant late culminant morphology
DBS0237998 triA-/ [act15]: GFPtriAaberrant late culminant morphology
DBS0237999 triA-/ [ecmAO]: lacZ: [ecmAO]: gustriAincreased prestalk O cell differentiation
DBS0238001 triA-/ [psA]: lacZ: [psA]: gustriAincreased prespore cell differentiation
DBS0351605 trm9-trm9decreased protein level
DBS0350107 tsc2-tsc2decreased phagocytosis
DBS0237022 tsg101-tsg101decreased fruiting body size
DBS0351612 tsg101-tsg101aberrant cellular process | decreased protein localization | increased defense response to Gram-positive bacterium
DBS0350816 tspC-tspCaberrant response to osmotic stress
HM1725 tstD-tstDdecreased growth rate | decreased plasma membrane organization | increased growth rate
DBS0302370 tsuA-tsuAincreased oscillatory cAMP signaling | abolished establishment of cell polarity | aberrant chemotaxis to folate | aberrant chemotaxis to cAMP | delayed aggregation | decreased mound size | decreased fruiting body size | aberrant pseudopodium formation
DBS0302383 tsuA-/ [unk]: tsuA(1-1774): YFPtsuAabolished protein localization to microtubules | abolished protein localization to microtubule organizing center | decreased mound size | decreased fruiting body size
DBS0302385 tsuA-/ [unk]: tsuA(1-260): YFPtsuAabolished protein localization to microtubules | abolished protein localization to microtubule organizing center | decreased mound size | decreased fruiting body size
DBS0302384 tsuA-/ [unk]: tsuA(1774-2247): YFPtsuAabolished protein localization to microtubules | abolished protein localization to microtubule organizing center | decreased mound size | decreased fruiting body size
DBS0302382 tsuA-/ [unk]: tsuA(K34R): YFPtsuAdecreased mound size | decreased fruiting body size
DBS0302381 tsuA-/ [unk]: tsuA: YFPtsuAwild type
DBS0237024 ubcB-ubcBincreased number of tip-organizers | development arrests at mound stage
DBS0306165 ube2t-ube2tdecreased resistance to cisplatin
DBS0237025 ubpA-ubpAdecreased gene expression | decreased chemotaxis rate | abolished aggregation
DBS0237026 ubpB-ubpBaberrant sorus morphology | increased prestalk gene expression | decreased prespore gene expression | precocious development
DBS0351464 uduB-/ AX3uduBincreased prestalk cell differentiation
DBS0237027 ufc1-ufc1wild type
DBS0237028 ugpB-/ DH1ugpBabolished sporulation | decreased glycogen level | aberrant cell differentiation | decreased fruiting body size | delayed culmination
DBS0266763 ugpB-/ DH1ugpBdecreased stalk length
DBS0266764 ugpB-/ HMXugpBabolished cellulose biosynthesis | decreased autophagic vacuole organization | aberrant cell morphology
DBS0350591 uppA-uppAdecreased catalytic activity
DBS0237031 vacA-vacAwild type
DBS0351567 vacA-vacAdecreased phagocytosis
DBS0237032 vacB-vacBdecreased exocytosis | increased defense response to bacterium
DBS0351568 vacB-vacBdecreased phagocytosis
DBS0351570 vacB-/ vacC-vacB | vacCdecreased phagocytosis
DBS0351569 vacC-vacCdecreased phagocytosis
DBS0237034 vasP-vasPabolished filopodium formation
DBS0237035 vasP-vasPdecreased lateral pseudopodium retraction | decreased cell-substrate adhesion | decreased vegetative cell size | decreased cell motility | decreased chemotaxis rate | aberrant hyperosmotic response | aberrant actin filament organization | decreased chemotaxis to cAMP | abolished filopodium formation | decreased filopodium formation
DBS0237033 vasP-/ [act15]: GFP: vasP(1-264/ 285-380)vasPabolished filopodium formation
DBS0237836 vasP-/ [act15]: YFP: wipAvasP | wipAdecreased filopodium formation
DBS0237842 vasP-/ [act15]: YFP: wipA/ [act15]: vasP: FLAGvasP | wipAincreased filopodium formation
DBS0351313 vasP-/ [act15]: abpB(129-295)abpB | vasPaberrant cellular process
DBS0351300 vasP-/ [act15]: eYFP: vasP(S141A)vasPdecreased protein localization to cell cortex | wild type | decreased lateral pseudopodium retraction | decreased establishment of cell polarity | aberrant actin filament organization
DBS0351301 vasP-/ [act15]: eYFP: vasP(S141D)vasPaberrant hyperosmotic response | decreased filopodium formation
DBS0237036 vasP-/ [act15]: myr: vasPvasPincreased filopodium formation | aberrant cytokinesis | increased actin filament polymerization
DBS0237040 vasP-/ [act15]: vasPvasPdecreased filopodium formation
DBS0237840 vasP-/ [act15]: vasPvasPincreased filopodium formation | increased actin filament polymerization
DBS0237037 vasP-/ [act15]: vasP(1-110: 231-380)vasPaberrant cytokinesis | increased actin filament polymerization | decreased filopodium formation
DBS0237038 vasP-/ [act15]: vasP(1-228)vasPdecreased filopodium formation
DBS0237039 vasP-/ [act15]: vasP(111-380)vasPincreased filopodium formation | increased actin filament polymerization
DBS0350466 vasP-/ [unk]: vasP(1-197: 221-380)vasPwild type
DBS0350467 vasP-/ [unk]: vasP(1-261: 285-380)vasPdecreased cell motility | abolished filopodium formation
DBS0350602 vilA-vilAdecreased chemotaxis to cAMP | decreased phototaxis
DBS0236058 vmp1-vmp1aberrant aggregation | decreased exocytosis | increased cell death | aberrant autophagy | decreased gene expression | decreased growth rate | aberrant hypotonic response | decreased macropinocytosis | aberrant vacuole organization | aberrant protein localization to autophagosome | aberrant protein localization | aberrant signal transduction
DBS0351250 vmp1-/ [act15]: vmp1(G268L): GFPvmp1aberrant aggregation | aberrant protein localization to autophagosome
DBS0350873 vps13F-vps13Faberrant defense response to bacterium | decreased growth rate
DG1118 vps46-vps46increased sorus size
DBS0237046 vwkA-vwkAincreased myosin II assembly | decreased growth rate | aberrant cytokinesis | aberrant contractile vacuole morphology | aberrant hypotonic response | delayed development | increased protein level | aberrant fruiting body morphogenesis | decreased contractile vacuole discharge
DBS0350290 vwkA-/ [act15]: GFP: mhcAmhcA | vwkAaberrant myosin II filament organization
TL61 wacA-wacAwild type
TL99 wacA-wacAwild type
DBS0237048 warA-warAdevelopment arrests at slug stage | increased basal disc size | decreased prespore cell differentiation | increased prestalk O cell differentiation
DBS0237049 warA-warAdevelopment arrests at slug stage | increased basal disc size | decreased prespore cell differentiation | increased prestalk O cell differentiation
DBS0351506 wasA-wasAaberrant protein localization to trailing edge
DBS0351509 wasA-/ [tet]: scrA/ [unk]: GFP: wasA(I173A/ F179A)scrA | wasAaberrant pseudopodium formation
DBS0351508 wasA-/ [unk]: GFP: wasA(I173A/ F179A)wasAaberrant protein localization to trailing edge | decreased establishment of cell polarity
DBS0350254 wasB-wasBabolished protein localization to cytoplasmic vesicle | aberrant chemotaxis to cAMP | increased actin filament polymerization | increased protein level | aberrant pseudopodium formation
DBS0350255 wasB-/ [act15]: YFP: wasBwasBwild type
DBS0351525 wasC-wasCincreased actin filament polymerization | decreased phagocytosis | increased cell-substrate adhesion | decreased chemotaxis rate
DBS0350239 washc5-washc5abolished exocytosis | decreased protein level | decreased growth rate | decreased phagocytosis | aberrant endosome morphology | decreased vegetative cell size | abolished phagosome reneutralization | decreased secretion of lysosomal enzymes | abolished actin filament polymerization | aberrant lysosome organization
DBS0351185 washc5-/ [act15]: washc5(N457D): GFPwashc5abolished exocytosis
DG1053 wimA-wimAaberrant fruiting body morphogenesis
DG1064 wimA-wimAaberrant fruiting body morphogenesis
DBS0349863 wshA-wshAincreased protein localization | abolished exocytosis | decreased defense response to Gram-negative bacterium | decreased macroautophagy | abolished endocytic recycling | aberrant vegetative growth | decreased phagocytosis | decreased protein processing in phagocytic vesicle | aberrant phagosome maturation | abolished phagosome reneutralization | decreased secretion of lysosomal enzymes | increased defense response to Gram-positive bacterium | decreased protein localization | aberrant lysosome organization | aberrant protein localization
DBS0350943 xacA-xacAdecreased hypotonic response | aberrant contractile vacuole morphology | aberrant actin filament organization
DBS0350950 xacA-xacAincreased lateral pseudopodium formation | decreased chemotaxis to cAMP | aberrant actin filament organization
DBS0350944 xacA-/ [act15]: xacA(1-320)xacAdecreased growth rate | aberrant cytokinesis
DBS0350945 xacA-/ [act15]: xacA(779-1335)xacAdecreased hypotonic response | aberrant contractile vacuole morphology
HM1456 xpc-xpcwild type | aberrant vegetative growth
HM1403 xpf-xpfaberrant vegetative growth | decreased resistance to cisplatin
AK235 yakA-yakAabolished aggregation
AK800 yakA-yakAdecreased protein localization to cell cortex | decreased gene expression | aberrant cell cycle | increased cellular thermotolerance | aberrant gene expression | decreased protein kinase activation | abolished aggregation | aberrant response to oxidative stress | aberrant cellular response to stress | decreased cAMP level
DBS0237087 yakA-/ AX3yakAdecreased growth rate | abolished aggregation | abolished actin filament polymerization | decreased cGMP biosynthesis
DBS0237091 yakA-/ [crlA]: crlAcrlA | yakAabolished vegetative growth
DBS0350058 yakA-/ keaA-keaA | yakAwild type
DBS0350898 yelA-/ AX2yelAprecocious prestalk gene expression | increased basal disc size
DG1014 yelA-/ AX4yelAaberrant spore morphology | precocious sporulation | development arrests at mound stage | aberrant mound color | aberrant sporulation
DBS0349797 zak2-zak2decreased prespore gene expression | decreased protein kinase activation | aberrant fruiting body morphogenesis | decreased sporulation
DBS0349883 zak2-/ [act15]: GFPzak2decreased sporulation
DBS0349798 zak2-/ [ecmA]: LacZzak2aberrant prestalk gene expression
DBS0349882 zak2-/ [ecmA]: zakAzak2 | zakAprecocious prestalk gene expression
ARK100-110 zakA-zakAabolished stream development | decreased protein kinase activity | increased prestalk gene expression | decreased prespore gene expression | aberrant fruiting body morphogenesis | decreased chemotaxis to cAMP | delayed culmination | decreased sporulation
DBS0238142 zakA-zakAdevelopment arrests at tipped mound stage
DBS0349803 zakA-/ [ecmB]: LacZzakAaberrant prestalk gene expression
DG1050 zipA-zipAdecreased fruiting body size
DBS0350068 zizB-zizBaberrant fruiting body morphogenesis | delayed development | decreased chemotaxis to cAMP

Last updated July 28, 2024

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