| Reference | Species | Genes Addressed |
|---|
A R, et al. (2025) Hyphal induction in Candida albicans: Optimizing medium parameters to accelerate hyphal growth enhanced by GlcNAc. J Microbiol Methods 238:107282 CGD Papers Entry Pubmed Entry | C. albicans | |HGC1 |HWP1 |
Basrani S, et al. (2025) Repurposing of quinine as an antifungal antibiotic: Identification of molecular targets in Candida albicans. Folia Microbiol (Praha) CGD Papers Entry Pubmed Entry | C. albicans | |ALS1 |CAP1 |CAT1 |KRE9 |MCA1 |SOD1 |SOD2 |
Buonanno A, et al. (2025) The Biotherapeutic Potential of a Novel Probiotic Kluyveromyces marxianus Isolated from a Sourdough Starter Against Vaginal Candida albicans Strains. J Fungi (Basel) 11(2) CGD Papers Entry Pubmed Entry | C. albicans | |SAP2 |SAP6 |
Camilo Pattini V, et al. (2025) 2-Hydroxy-dibenzylideneacetone as a multifunctional coating inhibiting biofilm formation of Candida albicans. J Appl Microbiol CGD Papers Entry Pubmed Entry | C. albicans | |ALS3 |ALS5 |HWP1 |
Fleres G, et al. (2025) Blood cultures contain populations of genetically diverse Candida albicans strains that may differ in echinocandin tolerance and fitness. J Infect Dis CGD Papers Entry Pubmed Entry | C. albicans | |NRG1 |
Jia H, et al. (2025) Discovery of novel azole derivatives with benzanilide-containing hydrophobic side chains for the treatment of drug-resistant fungal infections. RSC Adv 15(13):10170-10182 CGD Papers Entry Pubmed Entry | C. albicans | |CDR1 |ERG11 |
Jiang L, et al. (2025) Triazine amine compounds synergistically enhance the efficacy against fluconazole-resistant Candida albicans with fluconazole by inhibiting cell wall synthesis. Biochem Pharmacol 241:117181 CGD Papers Entry Pubmed Entry | C. albicans | |CHS1 |CHS8 |GSC1 |GSL1 |HOG1 |WSC1 |WSC2 |
Jothi R, et al. (2025) Lupeol mitigates biofilm formation and attenuates virulence dimorphism in Candida albicans. Microb Pathog 208:107989 CGD Papers Entry Pubmed Entry | C. albicans | |CPH1 |EFG1 |HWP1 |RAS1 |TUP1 |UME6 |
Kim YG, et al. (2025) Targeting biofilm formation in Candida albicans with halogenated pyrrolopyrimidine derivatives. Eur J Med Chem 290:117528 CGD Papers Entry Pubmed Entry | C. albicans | |ALS3 |CDR11 |CSR1 |ECE1 |GST3 |HWP1 |IFD1 |IFD6 |UCF1 |UME6 |YWP1 |
Liao B, et al. (2025) Aloin remodels the cell wall of Candida albicans to reduce its hyphal virulence against oral candidiasis. Appl Microbiol Biotechnol 109(1):21 CGD Papers Entry Pubmed Entry | C. albicans | |ALS3 |BCR1 |BIG1 |BMT9 |CBK1 |CHT2 |CSA1 |ECE1 |ECM21 |GSC1 |GSL1 |HWP1 |HYR1 |PGA10 |MORE |
Mishra A, et al. (2025) Strain background interacts with chromosome 7 aneuploidy to determine commensal and virulence phenotypes in Candida albicans. PLoS Genet 21(6):e1011650 CGD Papers Entry Pubmed Entry | C. albicans | |NRG1 |
Suwannaphong P, et al. (2025) Fluconazole tolerance and virulence adaptations of Candida albicans isolated from head and neck cancer patients. J Oral Microbiol 17(1):2559024 CGD Papers Entry Pubmed Entry | C. albicans | |ALS1 |ALS3 |CDR1 |CDR2 |ERG11 |HWP1 |MDR1 |SAP6 |
Watchaputi K, et al. (2025) Yeast-derived glycolipids disrupt Candida biofilm and inhibit expression of genes in cell adhesion. Sci Rep 15(1):20405 CGD Papers Entry Pubmed Entry | C. albicans | |ACE2 |
Wen J, et al. (2025) Long-term antifungal drug-delivery denture materials with plasma-initiated surface functionalization. Colloids Surf B Biointerfaces 256(Pt 2):115077 CGD Papers Entry Pubmed Entry | C. albicans | |UME6 |
Williams C, et al. (2025) Bio-orthogonal Labeling of Chitin in Native Pathogenic Candida Species via the Chitin Scavenge Pathway. J Am Chem Soc CGD Papers Entry Pubmed Entry | C. albicans | |HXK1 |NGT1 |
Zhang H, et al. (2025) 2-Chloromethyl anthraquinone inhibits Candida albicans biofilm formation by inhibiting the Ras1-cAMP-Efg1 pathway. Res Microbiol :104280 CGD Papers Entry Pubmed Entry | C. albicans | |ALS1 |BCR1 |CPH1 |CYR1 |ECE1 |HWP1 |RAC1 |TEC1 |TPK2 |UME6 |
Zhang M, et al. (2025) Lanosterol 14alpha-Demethylase (CYP51)/Heat Shock Protein 90 (Hsp90) Dual Inhibitors for the Treatment of Invasive Candidiasis. J Med Chem CGD Papers Entry Pubmed Entry | C. albicans | |ACE2 |ALS3 |BCR1 |CPH1 |CSR1 |EAP1 |EFG1 |ERG11 |ERG25 |ERG26 |ERG27 |ERG3 |ERG6 |HSP90 |MORE |
Zhang Y, et al. (2025) Adaptive evolution of Candida albicans through modulating TOR signaling. MBio :e0394724 CGD Papers Entry Pubmed Entry Web Supplement Data | C. albicans | |HYR1 |SAP6 |TOR1 |UME6 |
Zhu S, et al. (2025) Chemical Composition of the Traditional Chinese Medicine Compound (ICAM), its Antifungal Effects against Candida albicans, and the Underlying Mechanisms: Therapeutic Potential and Safety Evaluation for Vulvovaginal Candidiasis. J Ethnopharmacol :119844 CGD Papers Entry Pubmed Entry | C. albicans | |ALS3 |CDC24 |CEK1 |CHT2 |CSH1 |ECE1 |GFA1 |GRP2 |HGC1 |HST7 |HWP1 |MSB2 |PMM1 |PMT1 |MORE |
Basrani ST, et al. (2024) Antifungal Activity of Mefloquine Against Candida albicans Growth and Virulence Factors: Insights Into Mode of Action. Curr Microbiol 81(7):213 CGD Papers Entry Pubmed Entry | C. albicans | |ALS1 |KRE9 |MCA1 |SOD1 |SOD2 |
Basrani ST, et al. (2024) Hydroxychloroquine an Antimalarial Drug, Exhibits Potent Antifungal Efficacy Against Candida albicans Through Multitargeting. J Microbiol CGD Papers Entry Pubmed Entry | C. albicans | |CAP1 |CTN1 |CYR1 |HWP1 |MCA1 |RAS1 |SOD1 |SOD2 |TEC1 |
Bekirian C, et al. (2024) beta-1,6-Glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall. Elife 13 CGD Papers Entry Pubmed Entry | C. albicans | |CHS1 |CHS2 |CHS3 |KRE1 |KRE5 |KRE6 |KRE62 |MNN2 |MNN21 |MNN22 |MNN23 |MNN24 |MNN26 |MNN9 |MORE |
Chao W, et al. (2024) Antifungal Tetrahydrocarbazole Compound CAR-8 Induces Endoplasmic Reticulum Stress in Candida albicans. ACS Infect Dis CGD Papers Entry Pubmed Entry | C. albicans | |CDC48 |HAC1 |IRE1 |PRE2 |PRE3 |RPN2 |UBC15 |
Chen M, et al. (2024) Heterologous expression of the insect SVWC peptide WHIS1 inhibits Candida albicans invasion into A549 and HeLa epithelial cells. Front Microbiol 15:1358752 CGD Papers Entry Pubmed Entry | C. albicans | |ALS1 |ALS3 |ALS5 |CSR1 |ECE1 |EFG1 |HGC1 |HWP1 |SAP6 |
Chen Y, et al. (2024) Anti-Biofilm Activity of Assamsaponin A, Theasaponin E1, and Theasaponin E2 against Candida albicans. Int J Mol Sci 25(7) CGD Papers Entry Pubmed Entry | C. albicans | |ALS1 |ALS3 |CPH1 |DEF1 |EAP1 |EFG1 |HGC1 |HWP1 |HYR1 |PLB1 |RAS1 |SAP5 |UME6 |
Chougule S, et al. (2024) Zingerone effect against Candida albicans growth and biofilm production. J Mycol Med 35(1):101527 CGD Papers Entry Pubmed Entry | C. albicans | |BCY1 |CAP1 |CAT1 |CEK1 |CPH1 |ECE1 |EFG1 |HST7 |HWP1 |MCA1 |MIG1 |NRG1 |PDE2 |SOD1 |MORE |
Fong JL, et al. (2024) Biochemical Characterization of Recombinant Enterococcus faecalis EntV Peptide to Elucidate Its Antihyphal and Antifungal Mechanisms against Candida albicans. ACS Infect Dis CGD Papers Entry Pubmed Entry | C. albicans | |SPA2 |
Gayatri M, et al. (2024) Novel thiazolinyl-picolinamide-based palladium(II) complex extenuates the virulence and biofilms of vulvovaginal candidiasis (VVC) causing Candida. Int Microbiol CGD Papers Entry Pubmed Entry | C. albicans | |EFG1 |ERG1 |HGC1 |UME6 |
Ji Y, et al. (2024) The antimicrobial property of JY-1, a complex mixture of Traditional Chinese Medicine, is linked to it abilities to suppress biofilm formation and disrupt membrane permeability. Microb Pathog :106573 CGD Papers Entry Pubmed Entry | C. albicans | |ALS3 |HWP1 |
Khan MA, et al. (2024) In Silico and In Vitro Studies to Explore the Effect of Thymoquinone on Isocitrate Lyase, Biofilm Formation, and the Expression of Some Virulence Genes in Candida albicans. Curr Issues Mol Biol 46(11):12951-12967 CGD Papers Entry Pubmed Entry | C. albicans | |ALS1 |HWP1 |ICL1 |