| Reference | Species | Genes Addressed |
|---|
Basrani S, et al. (2025) Repurposing of quinine as an antifungal antibiotic: Identification of molecular targets in Candida albicans. Folia Microbiol (Praha) CGD Papers Entry Pubmed Entry | C. albicans | |ALS1 |CAP1 |CAT1 |KRE9 |MCA1 |SOD1 |SOD2 |
Bila NM, et al. (2025) Trichophyton rubrum inhibits Candida albicans filamentation and its gene expression when grown in biofilms in vitro. Mem Inst Oswaldo Cruz 120:e240221 CGD Papers Entry Pubmed Entry | C. albicans | |CPH1 |EFG1 |HWP1 |
Buonanno A, et al. (2025) The Biotherapeutic Potential of a Novel Probiotic Kluyveromyces marxianus Isolated from a Sourdough Starter Against Vaginal Candida albicans Strains. J Fungi (Basel) 11(2) CGD Papers Entry Pubmed Entry | C. albicans | |SAP2 |SAP6 |
Chavez JF, et al. (2025) Virulence Factors and Molecular Identification of Candida Species Causing Candidemia in Honduras. J Fungi (Basel) 11(7) CGD Papers Entry Pubmed Entry | C. albicans | |ITS1 |ITS2 |
Chougule S, et al. (2025) Alpha-bisabolol inhibits yeast to hyphal form transition and biofilm development in Candida albicans: in vitro and in silico studies. In Silico Pharmacol 13(1):53 CGD Papers Entry Pubmed Entry | C. albicans | |CST20 |RAS1 |TUP1 |
Consuegra-Asprilla JM, et al. (2025) Virulence of Candida spp. Isolates From Patients With Recurrent Vulvovaginal Candidosis Is Associated With the Number of Episodes. Mycoses 68(2):e70031 CGD Papers Entry Pubmed Entry | C. albicans | |PRA1 |
Costa TL, et al. (2025) Preventing Oral Dual Biofilm Development with Innovative Bioactive Varnishes. J Funct Biomater 16(2) CGD Papers Entry Pubmed Entry |
Czucz Varga J, et al. (2025) Mixed Candida albicans-Staphylococcus aureus Biofilm Is Reduced by Light-Activated Nanocomposite with Phloxine B. J Fungi (Basel) 11(8) CGD Papers Entry Pubmed Entry | C. albicans | |ALS3 |HWP1 |
Dias LM, et al. (2025) Unlocking Histatin Potential against Candida albicans and Streptococcus mutans Biofilms: Targeting the Extracellular Matrix While Preserving Oral Cell Integrity. ACS Omega 10(25):27011-27022 CGD Papers Entry Pubmed Entry |
El Hady R, et al. (2025) Phenotypic and genotypic characterization of Candida parapsilosis complex isolates from a Lebanese hospital. Sci Rep 15(1):4853 CGD Papers Entry Pubmed Entry | C. parapsilosis | |ALS6 |ALS7 |CDR1 |ERG11 |ERG6 |SAP7 |SAP9 |SAPP3 |UPC2 |
Eshimy R, et al. (2025) A novel clotrimazole selenium nano-composite for combating deep dermal Candida albicans infections and virulence genes. J Antibiot (Tokyo) CGD Papers Entry Pubmed Entry | C. albicans | |ALS1 |CDR1 |ERG11 |PLB1 |
Fayed B, et al. (2025) Comparative evaluation of biologically and chemically synthesized zinc oxide nanoparticles for preventing Candida auris biofilm. Biometals CGD Papers Entry Pubmed Entry | C. auris | |ALS5 |CDR1 |CSA1 |ERG11 |ERG2 |FKS1 |IFF4 |MDR1 |
Fleres G, et al. (2025) Blood cultures contain populations of genetically diverse Candida albicans strains that may differ in echinocandin tolerance and fitness. J Infect Dis CGD Papers Entry Pubmed Entry | C. albicans | |NRG1 |
Guo YD, et al. (2025) Hyssopus cuspidatus Boriss Volatile Extract (SXC): A Dual-Action Antioxidant and Antifungal Agent Targeting Candida albicans Pathogenicity and Vulvovaginal Candidiasis via Host Oxidative Stress Modulation and Fungal Metabolic Reprogramming. Antioxidants (Basel) 14(9) CGD Papers Entry Pubmed Entry | C. albicans | |ALS3 |CYR1 |ECE1 |EFG1 |HWP1 |PDE2 |RAS1 |TUP1 |UME6 |
Jia H, et al. (2025) Discovery of novel azole derivatives with benzanilide-containing hydrophobic side chains for the treatment of drug-resistant fungal infections. RSC Adv 15(13):10170-10182 CGD Papers Entry Pubmed Entry | C. albicans | |CDR1 |ERG11 |
Jiang L, et al. (2025) Triazine amine compounds synergistically enhance the efficacy against fluconazole-resistant Candida albicans with fluconazole by inhibiting cell wall synthesis. Biochem Pharmacol 241:117181 CGD Papers Entry Pubmed Entry | C. albicans | |CHS1 |CHS8 |GSC1 |GSL1 |HOG1 |WSC1 |WSC2 |
Jin HW and Eom YB (2025) Potent anti-biofilm properties of plumbagin against fluconazole-resistant Candida auris. J Tradit Complement Med 15(2):140-146 CGD Papers Entry Pubmed Entry | C. auris | |CDR1 |ERG11 |KRE6 |
Jothi R, et al. (2025) Lupeol mitigates biofilm formation and attenuates virulence dimorphism in Candida albicans. Microb Pathog 208:107989 CGD Papers Entry Pubmed Entry | C. albicans | |CPH1 |EFG1 |HWP1 |RAS1 |TUP1 |UME6 |
Karami-Feli M, et al. (2025) Antifungal Potential of Streptomyces-Derived Metabolites Against Fluconazole-Resistant Oral Candida albicans: In vitro Evaluation and Mechanistic Insights. Iran Biomed J CGD Papers Entry Pubmed Entry | C. albicans | |ERG11 |HWP1 |SAP1 |SAP2 |
Kim YG, et al. (2025) Targeting biofilm formation in Candida albicans with halogenated pyrrolopyrimidine derivatives. Eur J Med Chem 290:117528 CGD Papers Entry Pubmed Entry | C. albicans | |ALS3 |CDR11 |CSR1 |ECE1 |GST3 |HWP1 |IFD1 |IFD6 |UCF1 |UME6 |YWP1 |
Kumar AC, et al. (2025) Targeting fungal biofilms: design, synthesis, biological and in silico studies of novel N-(5-undecyl-1,3,4-oxadiazol-2-yl)benzamide derivatives against Candida albicans. Bioorg Med Chem 131:118425 CGD Papers Entry Pubmed Entry | C. albicans | |ALS1 |ALS3 |EFG1 |HWP1 |
Lee S, et al. (2025) Candida albicans biofilm extracellular vesicles deliver candidalysin to epithelial cell membranes and induce host cell responses. Infect Immun 93(5):e0040424 CGD Papers Entry Pubmed Entry | C. albicans | |ECE1 |
Li Y, et al. (2025) In vitro evaluation of tolerance ability of cross-kingdom biofilm towards oral dynamic fluctuations. BMC Oral Health 25(1):1216 CGD Papers Entry Pubmed Entry | C. albicans | |ALS1 |ALS3 |CAT1 |HWP1 |SOD1 |TRX1 |
Liang T, et al. (2025) Discovery of New Pyrazolone Carbothioamide Derivatives as Potent Antifungal Agents for the Treatment of Candidiasis and Cryptococcosis. J Med Chem CGD Papers Entry Pubmed Entry | C. albicans | |CAT1 |GPX1 |SOD1 |TRR1 |TRX1 |TSA1 |
| C. glabrata | |PDR1 |
Liu Y, et al. (2025) Activity of 6-methoxydihydrosanguinarine from Hylomecon japonica against wild-type and fluconazole-resistant Candida albicans biofilms. J Asian Nat Prod Res :1-12 CGD Papers Entry Pubmed Entry | C. albicans | |CYR1 |EFG1 |RAS1 |TPK2 |
Mendonca Dias L, et al. (2025) Salivary Proteins-Enhanced Antimicrobial Photodynamic Therapy: Overcoming Three Distinct Cultures of Resistant Mixed Biofilms. J Dent :105778 CGD Papers Entry Pubmed Entry |
Mezni G, et al. (2025) New Curcumin Analogue (PAC) Inhibits Candida albicans Virulence, Restricts Its Adhesion Potential, and Relieves Oral Epithelial Cell Inflammation and Defense Mechanisms. Antibiotics (Basel) 14(5) CGD Papers Entry Pubmed Entry | C. albicans | |EAP1 |HWP1 |SAP1 |SAP2 |SAP3 |SAP4 |SAP5 |SAP6 |SAP7 |SAP8 |SAP9 |
Mishra AP, et al. (2025) Characterization and enhanced antibiofilm activity of Annona muricata extract in combination with fluconazole against Candida albicans. Drug Target Insights 19:1-10 CGD Papers Entry Pubmed Entry | C. albicans | |SAP3 |
Nikoomanesh F, et al. (2025) Exploring the Antifungal Potential of Lawsone-Loaded Mesoporous Silica Nanoparticles Against Candida albicans and Candida glabrata: Growth Inhibition and Biofilm Disruption. J Fungi (Basel) 11(6) CGD Papers Entry Pubmed Entry | C. glabrata | |EPA1 |
| C. albicans | |ALS1 |
Nouraei H, et al. (2025) Overexpression of efflux pump and biofilm associated genes in itraconazole resistant Candida albicans isolates causing onychomycosis. Sci Rep 15(1):31292 CGD Papers Entry Pubmed Entry | C. albicans | |ALS1 |ALS3 |CDR1 |CDR2 |MDR1 |