| Reference | Species | Other Genes Addressed |
|---|
Miyazaki T, et al. (2025) Mechanisms of multidrug resistance caused by an Ipi1 mutation in the fungal pathogen Candida glabrata. Nat Commun 16(1):1023 CGD Papers Entry Pubmed Entry Web Supplement Data | C. glabrata | |CDR1 |CNA1 |CNB1 |IPI1 |IPI3 |PDH1 |PDR13 |RIX1 |SLT2 |SSB1 |SSB2 |
Gale AN, et al. (2023) Redefining pleiotropic drug resistance in a pathogenic yeast: Pdr1 functions as a sensor of cellular stresses in Candida glabrata. mSphere :e0025423 CGD Papers Entry Pubmed Entry Web Supplement Data | C. glabrata | |ATP1 |ATP2 |CAGL0J00297g |CAGL0L03828g |CDR1 |CIN5 |DAP1 |ERG11 |LSC2 |RPL28 |TRP1 |TRP2 |UPC2A |
Okamoto M, et al. (2023) In Candida glabrata, ERMES Component GEM1 Controls Mitochondrial Morphology, mtROS, and Drug Efflux Pump Expression, Resulting in Azole Susceptibility. J Fungi (Basel) 9(2) CGD Papers Entry Pubmed Entry | C. glabrata | |CDR1 |GEM1 |MDM10 |MDM12 |MDM34 |MMM1 |PDH1 |
Bhakt P, et al. (2022) The SET-domain protein CgSet4 negatively regulates antifungal drug resistance via the ergosterol biosynthesis transcriptional regulator CgUpc2a. J Biol Chem 298(10):102485 CGD Papers Entry Pubmed Entry Web Supplement Data | C. glabrata | |ARO10 |AUS1 |CDR1 |ERG11 |ERG3 |ERG4 |ERG5 |FKS2 |PDH1 |ROX1 |SET1 |SET2 |SET3 |SET4 |MORE |
Gaspar-Cordeiro A, et al. (2022) Zap1 is required for Candida glabrata response to fluconazole FEMS Yeast Res CGD Papers Entry Pubmed Entry | C. glabrata | |CDR1 |ZAP1 |
Tian Y, et al. (2020) A gain-of-function mutation in PDR1 of Candida glabrata decreases EPA1 expression and attenuates adherence to epithelial cells through enhancing recruitment of the Mediator subunit Gal11A. Microbiol Res 239:126519 CGD Papers Entry Pubmed Entry | C. glabrata | |EPA1 |GAL11A |
Paul S, et al. (2014) Identification of genomic binding sites for Candida glabrata Pdr1 transcription factor in wild-type and rho0 cells. Antimicrob Agents Chemother 58(11):6904-12 CGD Papers Entry Pubmed Entry Reference LINKOUT | C. albicans | |CDR1 |
| C. glabrata | |ATF2 |CAGL0A01650g |CAGL0B02101g |CAGL0C02937g |CAGL0E05588g |CAGL0I02574g |CAGL0I07249g |CAGL0J05852g |CAGL0K05819g |CAGL0K09702g |CDR1 |IPT1 |LAF1 |MEC3 |MORE |
Shahi P and Moye-Rowley WS (2009) Coordinate control of lipid composition and drug transport activities is required for normal multidrug resistance in fungi. Biochim Biophys Acta 1794(5):852-9 CGD Papers Entry Pubmed Entry Reference LINKOUT | C. albicans | |CDR1 |CDR1 |
| C. glabrata | |PDH1 |
Tsai HF, et al. (2006) Candida glabrata PDR1, a transcriptional regulator of a pleiotropic drug resistance network, mediates azole resistance in clinical isolates and petite mutants. Antimicrob Agents Chemother 50(4):1384-92 CGD Papers Entry Pubmed Entry Reference LINKOUT | C. glabrata | |CDR1 |PDH1 |
Vermitsky JP, et al. (2006) Pdr1 regulates multidrug resistance in Candida glabrata: gene disruption and genome-wide expression studies. Mol Microbiol 61(3):704-22 CGD Papers Entry Pubmed Entry Reference LINKOUT Reference LINKOUT | C. glabrata | |AMT1 |ATF2 |BMT2 |CAGL0A01650g |CAGL0A02816g |CAGL0A04543g |CAGL0B01078g |CAGL0B01969g |CAGL0B02343g |CAGL0B02981g |CAGL0B03014g |CAGL0B03355g |CAGL0C02981g |CAGL0D00946g |MORE |