Description:
Phosphorylation of S2789 and S2793 adjacent to the EBH-binding motif of Adenomatous polyposis coli protein (APC), by , respectively, gradually reduces the affinity of its interaction with Microtubule-associated protein RP/EB family member 1 (MAPRE1).
Participants:
(1) Adenomatous polyposis coli protein (APC)
(2) Microtubule-associated protein RP/EB family member 1 (MAPRE1)
(1) Structural insights into the EB1-APC interaction.
Honnappa et al. EMBO J. (2005)
(2) An EB1-binding motif acts as a microtubule tip localization signal.
Honnappa et al. Cell (2009)
Other switches involving participants
Microtubule-associated protein RP/EB family member 1 (MAPRE1) - 2 more (view)
Other switches involving interfaces
LIG_SxIP_EBH_1 - 2 more (view)
EB1-like C-terminal motif - 2 more (view)
