Drug-drug interaction between prescription and medication statement

@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
# - resource -------------------------------------------------------------------
[a fhir:DetectedIssue ;
 fhir:nodeRole fhir:treeRoot ;
 fhir:id [ fhir:v "ddi"] ; # 
 fhir:text [
 fhir:status [ fhir:v "generated" ] ;
 fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n <p><b>Severity: High</b> - Risk of internal bleeding</p>\n <p>Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding.</p>\n <ul>\n <li><a href=\"MedicationStatement/tylenol\">500 mg Acetaminophen tablet 1/day, PRN since 2010</a></li>\n <li><a href=\"MedicationRequest/warfarin\">Warfarin 1 MG TAB prescribed Jan. 5, 2014</a></li>\n </ul>\n <p>Mitigation: Jan 5, 2014 by Dr. Adam Careful: </p>\n <p>Asked patient to discontinue regular use of Tylenol and to consult with clinician if they need to resume to allow appropriate INR monitoring</p>\n </div>"
 ] ; # 
 fhir:status [ fhir:v "final"] ; # 
 fhir:category ( [
 fhir:coding ( [
 fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v3-ActCode"^^xsd:anyURI ] ;
 fhir:code [ fhir:v "DRG" ] ;
 fhir:display [ fhir:v "Drug Interaction Alert" ]
 ] )
 ] ) ; # 
 fhir:code [
 fhir:coding ( [
 fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v3-ActCode"^^xsd:anyURI ] ;
 fhir:code [ fhir:v "DRG" ] ;
 fhir:display [ fhir:v "Drug Interaction Alert" ]
 ] )
 ] ; # 
 fhir:severity [ fhir:v "high"] ; # 
 fhir:subject [
 fhir:reference [ fhir:v "Device/example" ]
 ] ; # 
 fhir:identified [ fhir:v "2014年01月05日"^^xsd:date] ; # 
 fhir:implicated ( [
 fhir:reference [ fhir:v "MedicationStatement/example001" ] ;
 fhir:display [ fhir:v "500 mg Acetaminophen tablet 1/day, PRN since 2010" ]
 ] [
 fhir:reference [ fhir:v "MedicationRequest/medrx0331" ] ;
 fhir:display [ fhir:v "Warfarin 1 MG TAB prescribed Jan. 15, 2015" ]
 ] ) ; # 
 fhir:detail [ fhir:v "Risk of internal bleeding. Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding."] ; # 
 fhir:mitigation ( [
 fhir:action [
 fhir:coding ( [
 fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v3-ActCode"^^xsd:anyURI ] ;
 fhir:code [ fhir:v "13" ] ;
 fhir:display [ fhir:v "Stopped Concurrent Therapy" ]
 ] ) ;
 fhir:text [ fhir:v "Asked patient to discontinue regular use of Tylenol and to consult with clinician if they need to resume to allow appropriate INR monitoring" ]
 ] ;
 fhir:date [ fhir:v "2014年01月05日"^^xsd:date ] ;
 fhir:author [
 fhir:reference [ fhir:v "Practitioner/example" ] ;
 fhir:display [ fhir:v "Dr. Adam Careful" ]
 ]
 ] )] . # 
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