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Entrez Programming Utilities Help
Introduction to the E-utilities
- Please see the E-utilities Introduction video for a brief introduction.
- Please see the Release Notes for details and changes.
The Entrez Programming Utilities (E-utilities) are a set of eight server-side programs that provide a stable interface into the Entrez query and database system at the National Center for Biotechnology Information (NCBI). The E-utilities use a fixed URL syntax that translates a standard set of input parameters into the values necessary for various NCBI software components to search for and retrieve the requested data. The E-utilities are therefore the structured interface to the Entrez system, which currently includes 38 databases covering a variety of biomedical data, including nucleotide and protein sequences, gene records, three-dimensional molecular structures, and the biomedical literature.
Contents
- E-utilities Quick Start Created: December 12, 2008; Last Update: October 24, 2018.
- Release Notes
- Announcement
- Introduction
- Searching a Database
- Uploading UIDs to Entrez
- Downloading Document Summaries
- Downloading Full Records
- Finding Related Data Through Entrez Links
- Getting Database Statistics and Search Fields
- Performing a Global Entrez Search
- Retrieving Spelling Suggestions
- Demonstration Programs
- For More Information
- A General Introduction to the E-utilities Created: May 26, 2009; Last Update: November 17, 2022.
- Sample Applications of the E-utilities Created: April 24, 2009; Last Update: November 1, 2017.
- Introduction
- Basic Pipelines
- ESearch – ESummary/EFetch
- EPost – ESummary/EFetch
- ELink – ESummary/Efetch
- ESearch – ELink – ESummary/EFetch
- EPost – ELink – ESummary/EFetch
- EPost – ESearch
- ELink – ESearch
- Application 1: Converting GI numbers to accession numbers
- Application 2: Converting accession numbers to data
- Application 3: Retrieving large datasets
- Application 4: Finding unique sets of linked records for each member of a large dataset
- Demonstration Programs
- For More Information
- The E-utilities In-Depth: Parameters, Syntax and More Created: May 29, 2009; Last Update: November 30, 2022.
- The E-utility Web Service (SOAP) Created: January 21, 2010; Last Update: January 23, 2015.
- Entrez Direct: E-utilities on the Unix Command Line Created: April 23, 2013; Last Update: March 25, 2025.