Figure 2: MF chimeras showed delayed sexual maturity and a prolonged oestrous cycle.
From: A genetically female brain is required for a regular reproductive cycle in chicken brain chimeras
(a) Onset of ovulation was significantly delayed in the MF chimeras as compared with FF chimeras and F controls. (b) MF chimeras produced fewer eggs. (c) The interval of ovulation was prolonged even in the constant light condition in the MF chimeras. Circles indicate the mean values of 10 days observation of individual animals. (d) Development of oocytes in the ovary. At 13–15 months (upper panels), MF chimeras had over-developed follicles (arrow) as well as necrotic follicles (arrowheads). Similarly, at about 24 months (lower panels), necrotic follicles were observed in MF chimeras. Scale bar, 10 mm. *P<0.05, ANOVA with Fisher’s PLSD. The numbers of animals used are indicated in the columns for a and b. Quantified data are presented as mean±s.e.m.