Back to Journals » Local and Regional Anesthesia » Volume 18

Original Research

The Diagonal Vector (DIVE) Approach for Lumbar Plexus Block – A Comparison with Chayen’s Technique

Authors Dumps C, Nothofer S , Weiss M, Hoelz W, Litz RJ, Bocher R, Kies F, Funk R, Heller AR, Simon P

Received 12 March 2025

Accepted for publication 22 July 2025

Published 19 August 2025 Volume 2025:18 Pages 67—76

DOI https://doi.org/10.2147/LRA.S527808

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Stefan Wirz



Christian Dumps,1 Stefanie Nothofer,1 Manfred Weiss,1 Wolfgang Hoelz,1 Rainer J Litz,2 Robert Bocher,2 Felicitas Kies,2 Richard Funk,3 Axel Rüdiger Heller,1,2 Philipp Simon1

1Anesthesiology and Operative Intensive Care, Faculty of Medicine, University of Augsburg, Bavaria, Germany; 2Department of Anesthesiology and Intensive Care Medicine, Medical Faculty Carl Gustav Carus, TU- Dresden, Saxony, Germany; 3Institute of Anatomy, Medical Faculty Carl Gustav Carus, TU Dresden, Saxony, Germany

Correspondence: Christian Dumps, Anesthesiology and Operative Intensive Care, Faculty of Medicine, University of Augsburg, Stenglinstrasse 2, 86156 Augsburg, Bavaria, Germany, Tel +49 0821 400 161492, Fax +49 0821 400 2198, Email [email protected]

Purpose: Substantial understanding of anatomic landmarks remains mandatory for regional anesthesia procedures of the lower limbs, even in times of ultrasound-guided techniques. Theoretically, applying a diagonal vector (DIVE) from the posterior superior iliac spine towards the spinous process of lumbar vertebra 3 leads to a higher error tolerance and closer nerve approximation when compared to Chayen’s approach. The purpose of this study was to compare both techniques regarding clinical applicability, accuracy and risk profile.
Patients and Methods: Lumbar plexus block was performed bilaterally according to Chayen’s technique and the DIVE method in embalmed bodies donated to science. The posterior medial half of the psoas major muscle was predefined as the puncture target area. Essential anatomical landmarks were labelled, photographed and a computer-aided analysis of the images was conducted. Both approaches were compared regarding the puncture success rate, spatial nerve approximation and complications such as vessel or kidney punctures.
Results: Both techniques were applied bilaterally on 34 embalmed bodies (50% male, mean age ± standard deviation 82 ± 8 years, height 167 ± 10cm) and led to similar success rates of a psoas muscle hit (Chayen vs DIVE 86.3% vs 82.8%). DIVE punctures were more often localized in the medial third of the psoas (p< 0.001), whereas the risk for vessel or kidney punctures was similar (p=0.473; p=0.367, respectively).
Conclusion: Punctures according to the DIVE method resulted in a higher puncture accuracy compared to Chayen’s technique with comparable practicability and risk profile. When using the DIVE Block, a window for a successful puncture can be expected between a quarter and a third of the PSIS- L3SP distance.

Keywords: regional anesthesia, lumbar plexus block, lower limb surgery, peripheral nerve block, local anesthetics

Introduction

Peripheral nerve block (PNB) techniques such as the posterior lumbar plexus block (LPB) play a crucial role in postoperative pain management after hip procedures such as total arthroplasty.1–5 Regional anesthesia enables early mobilisation active support in therapy, faster rehabilitation with good functional outcome and comparable pain control with fewer side effects, including neurologic and opioid-induced complications6–12 The LPB, also referred to as “psoas compartment block”, represents the most proximal peripheral approach for blocking the lumbar plexus (femoral, obturator and lateral cutaneous femoral nerve) mandatory for anesthesia of the lower extremity by a single puncture or injection.13,14 After Winnie first described an anterior perivascular (“3 in 1”) approach to the lumbar plexus in 1973 and later a posterior approach at the level of L4/L5, Chayen introduced a posterior L4 approach based on a loss of resistance in 1976.15–17 Even though several ultrasound-based approaches have been reported in body donors as well as in patients since then,18,19 broad understanding of relevant anatomical landmarks remains a fundamental aspect of all regional anaesthesia procedures, as this can prove beneficial when ultrasound guided approaches reach their limits.20–22 In 2009, Heller et al implemented the DIVE method by constructing a diagonal vector (DIVE) from the posterior superior iliac spine (PSIS) towards the spinous process (SP) of L3 (L3SP). In theory, the DIVE method is less dependent on individual anatomical variations and might lead to a higher error tolerance as well as closer spatial nerve approximation compared to previous approaches.23 However, there is currently no direct comparison of this method with one of the landmark-based approaches such as Chayen’s technique.

Thus, the objective of this prospective, experimental study was to evaluate the applicability, accuracy and risk profile of the DIVE method compared to Chayen’s clinically established approach to the LPB in human anatomical specimens.

Materials and Methods

Ethical Aspects

The bodies had been donated to the Department of Anatomy of the Medical Faculty Carl Gustav Carus of the Technical University Dresden under the Anatomical Donation Program, approved by the Technical University of Dresden. All body donors provided written informed consent to the conduct of studies and the use of the generated data for research purposes during their lifetime. The study was conducted in accordance with the Declaration of Helsinki adopted by the World Medical Association in October 2024.24

Preparation of Body Donors

Bodies were eviscerated, postured in a strict right lateral position and the LPB punctures were carried out bilaterally from posterior. To provide standardized spatial conditions and minimize projection errors or unwanted needle deviations, the bodies were positioned so that the body-related frontal plane was aligned exactly perpendicular to the horizontal plane of the table surface. Essential anatomical reference points were marked at the ventral and dorsal side of the bodies for photo documentation and subsequent analysis. LPB punctures were performed bilaterally with Chayen’s technique and with the DIVE method in each prepared body. The puncture sites were identified according to the respective landmarks in the lumbar region as originally described by Heller et al and Chayen et al16,23 The puncture depth was recorded with a centimeter-scaled (Contiplex Braun® 18G 110mm) needle at its exit point from the ventral surface of the psoas major muscle. For both approaches, the target area was predefined as the posterior medial half of the psoas major muscle in the frontal plane, since the true position of the lumbar plexus can be approximated at the border between the medial and the medium psoas third.23 Details regarding the puncture method, marking of essential anatomical reference points, photo documentation and the calculation of spatial distances are available in the Supplementary .

Statistical Analysis

All values are presented as mean ± standard deviation (SD). For comparisons of continuous variables between the two approaches of a posterior LPB two tailed, paired t-tests were performed. Levene’s test was used to check continuous variables for Gaussian distribution. Categorial variables were compared with the Chi2-test or, in case of expected cell frequencies <5, with the Fisher’s exact test. A polynomial fit procedure was performed to create an approximation curve and to calculate the closest proximity of the DIVE vector to the path of the nerve as represented at the respective curve minimum. SPSS software (IBM SPSS statistics, version 21.0.0.0, Armonk, NY, USA) was used for all calculations. A p-value of <0.05 was considered statistically significant.

Results

Body Donors

34 bodies donated to science and embalmed with 10% standard formalin solution were dissected and investigated. One body was excluded from further analysis due to severe scoliosis. A total of 132 punctures were carried out bilaterally in the remaining 33 bodies, with 66 according to Chayen’s approach and 66 by applying the DIVE method. General biometric data as well as parameters describing the anatomical configuration of the 33 specimens (17 female/ 16 male) were collected from both sides of the body to gain 66 side-specific anatomical datasets. The overall mean (± standard deviation) age was 82.1 ± 8.0 years (range 65–99 years), the mean body height was 167.2 ± 9.5cm (range 148–183cm). There was no difference regarding sex, height and age between the groups.

Comparison of the DIVE Method and Chayen’s Approach

We developed a two-dimensional scheme of the average anatomical configuration within a Cartesian coordinate system by integrating the mean positions of the SPs of L3, L4 and L5 the PSIS, the psoas major muscle and the caudal kidney pole in relation to the median longitudinal body axis and the intercristal line (Tuffier’s line, ICL). The average proximity of the needle insertion points on the DIVE vector to the lumbar plexus nerves was then calculated based on the acquired measurements (Figure 1a). The range of highest spatial approximation (< 9mm), given as the relation of the actual puncture vector to the DIVE vector was 0.1 to 0.33, corresponding to an average distance of the needle insertion point from the PSIS of 10–29mm. Unsuccessful punctures due to hitting osseous structures occurred in 21.2% of Chayen’s punctures and in 12.1% of DIVE punctures. Successful needle passages passing by osseous structures as well as potential osseous hindrances in the path of the DIVE vector are presented in Figures 1b and 2. An overview of the average DIVE vector length documented in case of a successful needle passage as well as the distances from the needle insertion point to relevant anatomical reference points is given in Table 1. All needle insertion points according to Chayen’s technique and their relation to anatomical reference points are shown in Figure 3a, those according to the DIVE method in Figure 3b. Figure 4a and b each show a dorsal view of a cadaver specimen with the needle insertion points according to the DIVE method and Chayen’s approach. Figure 4c presents a ventral view of the anatomical landmarks and puncture sites according to the DIVE and Chayen approaches, illustrated on a cadaver specimen. Punctures according to both techniques showed some degree of variability in relation to the median longitudinal body axis and the average ICL position. There was no difference in passing the needle into any part of the psoas muscle (Chayen vs DIVE: 78,8% vs 87,9%, p=0.243), however the DIVE punctures were more often localized within the medial third (33.3% vs 65.5%, p<0.001) as well as the medial half (47.1% vs 69.0%, p=0.032) of the psoas major muscle (see Table 2). For both methods, neither the side of the body nor sex had a significant influence on whether a puncture was placed within any part of the psoas major muscle. The mean approximation of the needle to the lumbar plexus was 7.1 ± 5.5mm with the DIVE method and 7.8 ± 6.4mm with Chayen’s approach (p=0.560). No accidental puncture of the kidneys occurred with the DIVE method. All five cases (4 according to DIVE, 1 according to Chayen) of unintentional paravertebral vessel punctures were located on the right side of the body. The average distance of the needle towards the parenchyma of the kidney was 52 ± 16mm with the DIVE method, which is larger than the average distance for Chayen’s punctures of 46 ± 16 mm (p=0.019).

Table 1 Average DIVE Vector Lengths and Distance to Anatomical Reference Points

Table 2 Comparison of Hit-Rates of Chayen’s and DIVE Approach

Figure 1 Theoretical and graphical representation of the DIVE vector. (a) Approximation curve of the DIVE vector to the lumbar plexus. Data are presented as mean ± standard error of the mean. The line connecting the posterior superior iliac spine (PSIS) with the tip of the spinous process of L3 is called DIVE vector (shown in Figure 1b). The x-axis depicts puncture entry points on the DIVE vector, given as a fraction from 0.1 to 0.5 (for example: if the total line measures 10 cm, 0.3 corresponds to a puncture point on this line at 3 cm from PSIS in direction to the spinous process of L3). The y-axis depicts the resulting distance of the needle tip to the presumed path of the lumbar plexus measured in mm. The calculated curve shows that punctures between 0.1 to 0.4 of the DIVE vector result in close proximity (8–9 mm) of the needle tip to the lumbar plexus. (b) Graphical representation of the DIVE vector. The DIVE vector (black dashed line) runs from the posterior superior iliac spine (PSIS) to the spinous process of lumbar vertebra 3 (L3SP). The red numbers depict puncture entry points on the DIVE vector, given as a fraction from 0.1 to 1.0 starting from the PSIS.

Abbreviations: SP; spinous process; TP; transverse process. TPL3, transverse process of lumbar vertebra 3; TPL4, transverse process of lumbar vertebra 4; TPL5, transverse process of lumbar vertebra 5; S, sacrum; L4SP, spinous process of lumbar vertebra 4; L5SP, spinous process of lumbar vertebra 5.

Figure 2 DIVE vector puncture points and corresponding osseous hindrances. The line connecting the posterior superior iliac spine (PSIS) with the tip of the spinous process of L3 (L3SP) is called DIVE vector (shown in Figures 1b and 3b). The y-axis depicts puncture entry points on the DIVE vector, given as fraction from 0.1 to 0.5 (for example: if the total line measures 10 cm, 0.3 corresponds to a puncture point on this line at 3 cm from PSIS in direction to L3SP). Red and Orange vertical chart bars show low success rates at these needle entry points due to osseous hindrances. Green bars demonstrate the numbers of successful punctures without osseous contact. L5: lumbar vertebra 5; TPL5: transverse process of lumbar vertebra 5.

Figure 3 Distribution of Punctures Using Chayen’s Approach and the DIVE Method. (a) Dispersion of punctures according to Chayen’s approach. Dispersion of the particular ventral exit sites of the needle with a successful puncture (x) in full frontal plane following Chayen’s approach (n = 52) with a depiction of the corresponding fixed metric measurements as well as the presumed path of the targeted neuronal structure (yellow lines) at the borderline between the medial and the medium third within the psoas major muscle (red lines). The dashed-dotted horizontal line represents the intercristal line, the vertical line the median longitudinal body axis. The grey ovals represent the left and right kidney. (b) Dispersion of punctures according to the DIVE method. Dispersion of the particular ventral exit sites of the needle with a successful puncture (x) in full frontal plane following the diagonal vector method (n=58) with a depiction of the corresponding fixed metric measurements as well as the presumed path of the targeted neuronal structure (yellow lines) at the borderline between the medial and the medium third within the psoas major muscle (red lines). The diagonal vector (DIVE vector), ie the line connecting the posterior superior iliac spine (PSIS) with the tip of the spinous process of L3, is indicated by a black arrow. The dashed-dotted horizontal line represents the intercristal line, the vertical line the median longitudinal body axis. The grey ovals represent the left and right kidney.

Figure 4 Anatomical views of LPB puncture sites: DIVE method vs Chayen’s approach in cadaver specimens. (a) Dorsal view of the LPB puncture using the DIVE method. Dorsal view of a cadaver torso in a craniocaudal orientation, positioned on its left side with the lateral side of the body at the top and the spine at the bottom. The blue needle on the left side towards the cranium represents the spinous process of the vertebral body of L3 and the blue needle on the right side towards the caudal pole represents the right posterior superior spina iliaca on the right side of the body. The yellow line represents the DIVE vector from PSIS to L3SP and the needle insertion point demonstrates a puncture according to the DIVE method. (b) Dorsal view of of LPB puncture using Chayen’s approach. Dorsal view of a cadaver torso (specimen No. 3) with the lateral side positioned at the top and the spine at the bottom in craniocaudal position with the cranium towards the right side and the caudal pole towards the left side of the picture. The blue needles represent the spinous processes of the vertebral bodies of L5 (L5SP), L4 (L4SP) and L3 (L3SP, left to right). The yellow arrows demonstrate the approach to the needle insertion point by marking a point 3 cm caudad (horizontal line) to L4 and from there 5 cm lateral. The insertion point of the green needle demonstrates a puncture according to Chayen’s approach. (c) Ventral view of the puncture sites according to the DIVE and Chayen’s approaches as well as relevant anatomical landmarks. Ventral view of a specimen’s abdominal retroperitoneal cavity with the cranium at the top and the lower body towards the bottom of the picture. The anatomical lancet represents the intercristal line. The aorta abdominalis anterior lies behind the lancet, dividing into the common iliac arteries below. The left and right lower kidney Poles are marked with blue needles. The green cannulas represent the projection of the posterior superior iliac spine (PSIS) on both sides and the yellow cannulas represent the vertical and horizontal borders of the promotorium of the sacral bone. The relevant anatomical landmarks are shown at the levels of L3 (red), L4 (yellow), and L5 (green), each from medial to lateral: the spinous process of L3 (L3 SP), L4 (L4 SP) and L5 (L5 SP), the lateral border of the vertebral body, and the lateral edge of the psoas muscle. Puncture sites according to the DIVE technique are marked in black, and those according to Chayen’s approach are marked in white. Note that a puncture following Chayen’s approach was not possible on the right side of the body due to persistent bony contact.

Discussion

This prospective experimental study is the first to examine the practicability and accuracy of the DIVE method in human specimens. The main finding of the present study is that an LPB puncture according to the DIVE method results in a higher spatial approximation to the lumbar plexus as well as a higher puncture accuracy with a similar risk profile and practicability compared to Chayen’s technique.

The DIVE method is based on the concept that using two anatomical reference points instead of just one as in Chayen’s technique increases lumbar plexus approximation and reduces errors in determining the correct insertion point as well as any associated complications due to interindividual anatomical variability and methodical imprecision.25–31 This theoretical advantage of the DIVE method was validated by the significantly higher precision and puncture accuracy within the target area being the medial half and median third of the psoas muscle (Figure 3a and b) as well as a lower failure rate due to a hit of osseous hindrances.23 Approximately 80% of successful punctures without any bone contact were localized within a range of 0.2 to 0.33 on the average DIVE vector in relation to its total length from PSIS to L3SP, as shown in Figure 3b, which coincidentally lay within the area of highest spatial approximation (< 9mm) of the DIVE vector towards the lumbar plexus, between 0.1 and 0.33 (Figure 1a). Based on these results, conducting a posterior LPB by using the DIVE method should be attempted primarily between 0.2 and 0.33 on the DIVE vector with a strictly perpendicular needle advancement.

When comparing the DIVE method with the established Chayen’s technique in terms of clinical practicality, aspects such as safety, complication potential and feasibility have to be considered. As the main nerves arising from the lumbar plexus relevant to lumbar plexus block run in the medial half of the psoas muscle, a more medial puncture according to the DIVE method potentially results in a higher success rate and a lower probability of organ damage compared to the more lateral Chayen’s approach. We observed a higher frequency of accidental major iliac and lumbar vessel punctures with the DIVE method, which run medial to the psoas muscle and supply paravertebral and back muscles. Even though the accidental vessel puncture rates in both approaches were not significantly different, it should be noted that LPB according to the DIVE method potentially increases the risk of accidental vessel punctures, especially on the right side, or unintended epidural local anesthetic spread due to the medial needle trajectory and the close anatomical relation to the intervertebral neuroforamina.32 The greater approximation of the DIVE vector to the path of the lumbar plexus in comparison with Chayen’s approach further implies that the lumbar plexus may be successfully localized within less time when applying the DIVE method under clinical circumstances in combination with ultrasound guidance. The higher proximity of the needle tip to the lumbar plexus nerves could potentially result in a more rapid onset of anesthesia after local anesthetic injection with a reduced amount of required local anesthetic. When combined with color doppler or power doppler ultrasound, the risk of accidental vessel punctures should, at least in theory, be minimized. However, since this study was carried out in body donors, we could not verify such a hypothesis.

Owing to recent technological advancements and widespread availability, ultrasound-based techniques are increasingly preferred in clinical practice. While ultrasound-guided techniques rightfully hold a prominent position when it comes to PNB techniques, previous studies have also pointed out important limitations, including the inability to visualize target nerves due to their intramuscular course and the limited spatial resolution associated with the low ultrasound frequencies required for these techniques.33,34 Therefore, landmark-based PNB techniques might offer several advantages and are essential, particularly in settings where ultrasound guidance reaches its limitations and is not feasible.35 They do not require specialized equipment, can often be performed more quickly by experienced practitioners and are not affected by poor image quality, which can be a major limitation in patients with obesity, altered anatomy or for unexperienced anesthesiologists. In this context, landmark-based techniques may present a steeper learning curve for trainees, allowing them to focus on anatomical and palpation skills before engaging with the complexity of ultrasound image interpretation.36 The present cadaveric study demonstrates the expected theoretical superiority of the DIVE method in terms of higher puncture accuracy, with a similar risk profile and practicability compared to Chayen’s technique, thereby contributing to improved patient care and safety.

There are some limitations to this experimental study. The clinical applicability of the results is limited by the three-dimensional tissue shrinkage caused by the chemical fixation of the bodies and the advanced mean age of 82 years which goes along with tissue trophism, increased calcification levels and size reduction of the psoas muscle.37,38 Additionally, the tissue layers of the cutis and subcutis had already been removed within the lumbar region, hence the presented puncture depths on the DIVE vector might be somewhat lower than they would be in living patients. Along with age and age-related changes of tissue composition, anatomical variations should be considered and systematically evaluated in a larger, broader and more diverse cohort of living subjects to assess the clinical applicability of the DIVE method. Regarding the anatomical limitations of the DIVE method, unsuccessful puncture attempts at the inferior limit of the DIVE vector are most probable due to contact with either the iliac crest or the sacrum. Punctures closer to L3SP occur due to osseous contact with the transverse process of L5 or potentially the vertebral body L5 (Figures 1b and 2). Punctures between 0.22 and 0.32, ie between a quarter and a third of the PSIS- L3SP distance, therefore, represent a window for a successful puncture. The lower success rate, which was observed at exactly 0.28 of the DIVE vector length, can only be explained as a random observation.

Conclusion

LPB by means of a puncture on the DIVE vector resulted in a closer approximation to the lumbar plexus and higher puncture accuracy with similar practicability and risk profile compared to Chayen’s technique. A window for successful puncture can be expected between a quarter and a third of the PSIS- L3SP distance. The DIVE method might offer the advantage of a higher success rate in patients or situations where ultrasound-guided approaches reach their limits and overall contribute to an improved quality, effectiveness and efficiency of this regional anesthetic procedure within modern perioperative patient care regimens.

Abbreviations

DIVE, diagonal vector; ICL, intercristal line (Tuffier’s line); L3SP, spinous process of the third lumbar vertebra; LPB, lumbar plexus block; PNB, peripheral nerve block; PSIS, posterior superior iliac spine; SP, spinous process.

Disclosure

The authors report no conflicts of interest in this work.

References

1. Fillingham YA, Hannon CP, Kopp SL, et al. The efficacy and safety of regional nerve blocks in total hip arthroplasty: systematic review and direct meta-analysis. J Arthroplasty. 2022;37(10):1922–1927e2. doi:10.1016/j.arth.2022年04月03日5

2. Migliorini F, Betsch M, Bardazzi T, et al. Management of postoperative pain following primary total knee arthroplasty: a level I evidence-based bayesian network meta-analysis. Pharmaceuticals. 2025;18(4):556. doi:10.3390/ph18040556

3. Raimer C, Priem K, Wiese AA, et al. Continuous psoas and sciatic block after knee arthroplasty: good effects compared to epidural analgesia or i.v. opioid analgesia: a prospective study of 63 patients. Acta Orthop. 2007;78(2):193–200. doi:10.1080/17453670710013672

4. Turker G, Uckunkaya N, Yavascaoglu B, Yilmazlar A, Ozcelik S. Comparison of the catheter-technique psoas compartment block and the epidural block for analgesia in partial Hip replacement surgery. Acta Anaesthesiol Scand. 2003;47(1):30–36. doi:10.1034/j.1399-6576.2003.470106.x

5. Lee JJ, Choi SS, Lee MK, Lim BG, Hur W. Effect of continuous psoas compartment block and intravenous patient controlled analgesia on postoperative pain control after total knee arthroplasty. Korean J Anesthesiol. 2012;62(1):47–51. doi:10.4097/kjae.2012621.47

6. Anger M, Valovska T, Beloeil H, et al. PROSPECT guideline for total Hip arthroplasty: a systematic review and procedure-specific postoperative pain management recommendations. Anaesthesia. 2021;76(8):1082–1097. doi:10.1111/anae.15498

7. Grinman L, Elmore B, Ardon AE, et al. Use of peripheral nerve blocks for total hip arthroplasty. Curr Pain Headache Rep. 2024;28(11):1113–1121. doi:10.1007/s11916-024-01287-7

8. Horlocker TT, Kopp SL, Pagnano MW, Hebl JR. Analgesia for total Hip and knee arthroplasty: a multimodal pathway featuring peripheral nerve block. J Am Acad Orthop Surg. 2006;14(3):126–135. doi:10.5435/00124635-200603000-00003

9. Fowler SJ, Symons J, Sabato S, Myles PS. Epidural analgesia compared with peripheral nerve blockade after major knee surgery: a systematic review and meta-analysis of randomized trials. Br J Anaesth. 2008;100(2):154–164. doi:10.1093/bja/aem373

10. Stein BE, Srikumaran U, Tan EW, Freehill MT, Wilckens JH. Lower-extremity peripheral nerve blocks in the perioperative pain management of orthopaedic patients: AAOS exhibit selection. J Bone Joint Surg Am. 2012;94(22):e167. doi:10.2106/JBJS.K.01706

11. Siddiqui ZI, Cepeda MS, Denman W, Schumann R, Carr DB. Continuous lumbar plexus block provides improved analgesia with fewer side effects compared with systemic opioids after Hip arthroplasty: a randomized controlled trial. Reg Anesth Pain Med. 2007;32(5):393–398. doi:10.1016/j.rapm.200704008

12. AlMutiri WA, AlMajed E, Alneghaimshi MM, et al. Efficacy of continuous lumbar plexus blockade in managing post-operative pain after hip or femur orthopedic surgeries: a systematic review and meta-analysis. J Clin Med. 2024;13(11). doi:10.3390/jcm13113194

13. Enneking FK, Chan V, Greger J, Hadzic A, Lang SA, Horlocker TT. Lower-extremity peripheral nerve blockade: essentials of our current understanding. Reg Anesth Pain Med. 2005;30(1):4–35. doi:10.1016/j.rapm.200410002

14. Sim IW, Webb T. Anatomy and anaesthesia of the lumbar somatic plexus. Anaesth Intensive Care. 2004;32(2):178–187. doi:10.1177/0310057X0403200204

15. Singelyn FJ, Capdevila X. Regional anaesthesia for orthopaedic surgery. Curr Opin Anaesthesiol. 2001;14(6):733–740. doi:10.1097/00001503-200112000-00022

16. Chayen D, Nathan H, Chayen M. The psoas compartment block. Anesthesiology. 1976;45(1):95–99. doi:10.1097/00000542-197607000-00019

17. Winnie A, Ramamurthy S, Durrani Z. Plexus blocks for lower extremity surgery. Anesthesiology Rev. 1974;1:11–16.

18. Karmakar MK, Li JW, Kwok WH, Soh E, Hadzic A. Sonoanatomy relevant for lumbar plexus block in volunteers correlated with cross-sectional anatomic and magnetic resonance images. Reg Anesth Pain Med. 2013;38(5):391–397. doi:10.1097/AAP.0b013e31829e52cc

19. Wang X, Zhang H, Chen Y, et al. The anesthetic efficacy of ultrasound-guided lumbar plexus combined with quadratus lumborum block with Shamrock approach in total Hip arthroplasty: study protocol for a randomized controlled trial. Trials. 2023;24(1):596. doi:10.1186/s13063-023-07619-z

20. Karmakar MK, Ho AM, Li X, Kwok WH, Tsang K, Ngan Kee WD. Ultrasound-guided lumbar plexus block through the acoustic window of the lumbar ultrasound trident. Br J Anaesth. 2008;100(4):533–537. doi:10.1093/bja/aen026

21. Steinfeldt T, Schwemmer U, Volk T, et al. Nerve localization for peripheral regional anesthesia. Recommendations of the German Society of Anaesthesiology and Intensive Care Medicine. Anaesthesist. 2014;63(7):597–602. doi:10.1007/s00101-014-2343-6

22. McLeod GA, Reina MA, Boezaart AP. High-definition ultrasound in regional anesthesia. Curr Opin Anaesthesiol. 2025. doi:10.1097/ACO.0000000000001534

23. Heller AR, Fuchs A, Rossel T, et al. Precision of traditional approaches for lumbar plexus block: impact and management of interindividual anatomic variability. Anesthesiology. 2009;111(3):525–532. doi:10.1097/ALN.0b013e3181af64b6

24. World Medical A. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2024;310(20):2191–2194. doi:10.1001/jama.2013.281053.

25. Snider KT, Snider EJ, Degenhardt BF, Johnson JC, Kribs JW. Palpatory accuracy of lumbar spinous processes using multiple bony landmarks. J Manipulative Physiol Ther. 2011;34(5):306–313. doi:10.1016/j.jmpt.201104006

26. Robinson R, Robinson HS, Bjorke G, Kvale A. Reliability and validity of a palpation technique for identifying the spinous processes of C7 and L5. Man Ther. 2009;14(4):409–414. doi:10.1016/j.math.200806002

27. Manolakos K, Zygogiannis K, Mousa C, Demesticha T, Protogerou V, Troupis T. Anatomical variations of the iliohypogastric nerve: a systematic review of the literature. Cureus. 2022;14(5):e24910. doi:10.7759/cureus.24910

28. Reske AW, Reske AP, Meier V, Wiegel M. Periphere Nervenblockaden an der unteren Extremitat. Klinisch-praktische Aspekte. [Peripheral nerve blocks of the lower extremities. Clinical and practical aspects]. Anaesthesist. 2009;58(10):1055–70;quiz1071. doi:10.1007/s00101-009-1610-4

29. Borghi B, Tognu A, White PF, et al. Soft tissue depression at the iliac crest prominence: a new landmark for identifying the L4-L5 interspace. Minerva Anestesiol. 2012;78(12):1348–1356.

30. Volk T, Engelhardt L, Spies C, et al. Infektionsinzidenz von Katheterverfahren zur Regionalanasthesie: erste Ergebnisse aus dem Netzwerk von DGAI und BDA. [Incidence of infection from catheter procedures for regional anesthesia: first results from the network of DGAI and BDA]. Anaesthesist. 2009;58(11):1107–1112. doi:10.1007/s00101-009-1636-7

31. Chakraverty R, Pynsent P, Isaacs K. Which spinal levels are identified by palpation of the iliac crests and the posterior superior iliac spines? J Anat. 2007;210(2):232–236. doi:10.1111/j.1469-7580.2006.00686.x

32. Gadsden JC, Lindenmuth DM, Hadzic A, Xu D, Somasundarum L, Flisinski KA. Lumbar plexus block using high-pressure injection leads to contralateral and epidural spread. Anesthesiology. 2008;109(4):683–688. doi:10.1097/ALN.0b013e31818631a7

33. Wiessner D, Litz RJ, Vicent O, Koch T, Heller AR. Psoas compartment block using ultrasonic guidance by a lateral view in patients-A451. Eur J Anaesthesiol. 2004;21:109–110. doi:10.1097/00003643-200406002-00398

34. Kirchmair L, Entner T, Wissel J, Moriggl B, Kapral S, Mitterschiffthaler G. A study of the paravertebral anatomy for ultrasound-guided posterior lumbar plexus block. Anesth Analg. 2001;93(2):477–81,4thcontentspage. doi:10.1097/00000539-200108000-00047

35. Dohlman LE, Kwikiriza A, Ehie O. Benefits and barriers to increasing regional anesthesia in resource-limited settings. Local Reg Anesth. 2020;13:147–158. doi:10.2147/LRA.S236550

36. Kessler P. Ultraschallgesteuerte Regionalanasthesie bei Adipositas. [Ultrasound-Guided Regional Anaesthesia in Obesity]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2019;54(4):268–281. doi:10.1055/a-0636-2759

37. Buford TW, Lott DJ, Marzetti E, et al. Age-related differences in lower extremity tissue compartments and associations with physical function in older adults. Exp Gerontol. 2012;47(1):38–44. doi:10.1016/j.exger.201110001

38. Zullo A, Fleckenstein J, Schleip R, Hoppe K, Wearing S, Klingler W. Structural and functional changes in the coupling of fascial tissue, skeletal muscle, and nerves during aging. Front Physiol. 2020;11:592. doi:10.3389/fphys.2020.00592

Creative Commons License © 2025 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, 4.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Recommended articles