UniProt:P49771 FLT3LG

chain
  • signal peptide:1-26
  • chain:27-235
checksum 73B95BF693B4CECF
comment
  • FUNCTION Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. Required for the development of B cells, and dendritic cells (DCs).SUBUNIT Homodimer (isoform 2).INTERACTION The disease may be caused by variants affecting the gene represented in this entry.
crossReference
databaseName UniProt
dbId 54890
description
  • recommendedName: Fms-related tyrosine kinase 3 ligand shortName: Flt3 ligand shortName: Flt3L alternativeName: SL cytokine
displayName UniProt:P49771 FLT3LG
geneName
  • FLT3LG
identifier P49771
isSequenceChanged false
keyword
  • 3D-structure
  • Alternative splicing
  • Cell membrane
  • Cytokine
  • Disulfide bond
  • Glycoprotein
  • Membrane
  • Proteomics identification
  • Reference proteome
  • Secreted
  • Signal
  • Transmembrane
  • Transmembrane helix
moleculeType Protein
name
  • FLT3LG
otherIdentifier
  • 1067_at
  • 1068_g_at
  • 11730099_a_at
  • 11730100_x_at
  • 11744800_x_at
  • 11748850_a_at
  • 16864129
  • 206980_PM_s_at
  • 206980_s_at
  • 210607_PM_at
  • 210607_at
  • 2323
  • 36314_at
  • 3838557
  • 3838558
  • 3838559
  • 3838560
  • 3838561
  • 3838562
  • 3838563
  • 3838564
  • 3838565
  • 3838566
  • 3838567
  • 3838568
  • 3838569
  • 3838570
  • 3838571
  • 3838573
  • 3838574
  • 8030339
  • A_14_P106481
  • A_23_P78742
  • GE81025
  • GE88850
  • GO:0002376
  • GO:0005102
  • GO:0005125
  • GO:0005515
  • GO:0005576
  • GO:0005615
  • GO:0005829
  • GO:0005886
  • GO:0007165
  • GO:0008284
  • GO:0009986
  • GO:0016020
  • GO:0030154
  • GO:0030183
  • GO:0030971
  • GO:0032819
  • GO:0035162
  • GO:0048018
  • GO:0048856
  • GO:0097028
  • GO:0098772
  • HMNXSV003035875
  • HMNXSV003050235
  • ILMN_2091412
  • PH_hs_0000051
  • TC19002605.hg
  • U03858_at
  • U04806_s_at
  • g4503750_3p_a_at
  • g494978_3p_at
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • FLT3L_HUMAN
  • A0AVC2
  • B9EGH2
  • Q05C96
sequenceLength 235
stId uniprot:P49771
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