Reactome Pathway Database

Schema > Reaction > Entries

O-atom dealkylation of dextromethorphan Show undefined attributes

catalystActivity

[CatalystActivity:10608353] monooxygenase activity of Cytochrome P450 (CYP2D6 based) [endoplasmic reticulum membrane]

category transition

compartment

created [InstanceEdit:10603480] Weiser, Joel, 2025年08月27日

dbId 10608355

displayName O-atom dealkylation of dextromethorphan

eventOf

[Pathway:R-XTR-211981] Xenobiotics - Xenopus tropicalis

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-76456] O-atom dealkylation of dextromethorphan - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

O-atom dealkylation of dextromethorphan

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:205621] Xenopus tropicalis

stId R-XTR-76456

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-XTR-211981] Xenobiotics

(inferredTo)

[Reaction:R-HSA-76456] O-atom dealkylation of dextromethorphan

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