Reactome Pathway Database

Schema > Reaction > Entries

PC carboxylates PYR to OA Show undefined attributes

catalystActivity

[CatalystActivity:10604666] pyruvate carboxylase activity of PC tetramer [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:10603480] Weiser, Joel, 2025年08月27日

dbId 10604668

displayName PC carboxylates PYR to OA

eventOf

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

goBiologicalProcess [GO_BiologicalProcess:15002] gluconeogenesis

inferredFrom

[Reaction:R-HSA-70501] PC carboxylates PYR to OA - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

PC carboxylates PYR to OA
PC catalyzes the carboxylation of PYR to form OA
ATP + hydrogencarbonate + pyruvate => ADP + H(+) + oxaloacetate + phosphate

output

precedingEvent

regulatedBy

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:205621] Xenopus tropicalis

stId R-XTR-70501

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-70501] PC carboxylates PYR to OA

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