Reactome Pathway Database

Schema > Reaction > Entries

Ceramide synthases transfer acyl-CoA onto sphingoid Show undefined attributes

catalystActivity

[CatalystActivity:10624116] sphingosine N-acyltransferase activity of Ceramide synthases [endoplasmic reticulum membrane]

category transition

compartment

created [InstanceEdit:10603480] Weiser, Joel, 2025年08月27日

dbId 10624118

displayName Ceramide synthases transfer acyl-CoA onto sphingoid

eventOf

[Pathway:R-XTR-1660661] Sphingolipid de novo biosynthesis - Xenopus tropicalis

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Ceramide synthases transfer acyl-CoA onto sphingoid
sphingoid + acyl-CoA => dihydroceramide + CoASH

output

precedingEvent

[Reaction:R-XTR-428123] KDSR reduces 3-ketosphingoid - Xenopus tropicalis

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:205621] Xenopus tropicalis

stId R-XTR-428185

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-XTR-1660661] Sphingolipid de novo biosynthesis

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-428185] Ceramide synthases transfer acyl-CoA onto sphingoid

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