Reactome Pathway Database

Schema > Reaction > Entries

HAO1 tetramer oxidizes glycolate to glyoxylate Show undefined attributes

catalystActivity

[CatalystActivity:10622337] (S)-2-hydroxy-acid oxidase activity of HAO1 tetramer [peroxisomal matrix]

category transition

compartment

[Compartment:17951] peroxisomal matrix

created [InstanceEdit:10603480] Weiser, Joel, 2025年08月27日

dbId 10622339

displayName HAO1 tetramer oxidizes glycolate to glyoxylate

eventOf

[Pathway:R-XTR-389661] Glyoxylate metabolism and glycine degradation - Xenopus tropicalis

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-389842] HAO1 tetramer oxidizes glycolate to glyoxylate - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

HAO1 tetramer oxidizes glycolate to glyoxylate
glycolate + O2 => glyoxylate + H2O2

output

precedingEvent

[Reaction:R-XTR-389826] glyoxylate + NADPH + H+ => glycolate + NADP+ - Xenopus tropicalis

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:205621] Xenopus tropicalis

stId R-XTR-389842

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-XTR-389661] Glyoxylate metabolism and glycine degradation

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-389842] HAO1 tetramer oxidizes glycolate to glyoxylate

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