Reactome Pathway Database

Schema > Reaction > Entries

CYP11B2 oxidises 11DCORST to CORST Show undefined attributes

catalystActivity

[CatalystActivity:10615458] steroid 11-beta-monooxygenase activity of Cytochrome P450 (CYP11B1 based) [mitochondrial inner membrane]

category transition

compartment

created [InstanceEdit:10603480] Weiser, Joel, 2025年08月27日

dbId 10615462

displayName CYP11B2 oxidises 11DCORST to CORST

eventOf

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-XTR-193995] CYP11B2 18-hydroxylates CORST to 18HCORST - Xenopus tropicalis

inferredFrom

[Reaction:R-HSA-194017] CYP11B2 oxidises 11DCORST to CORST - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

CYP11B2 oxidises 11DCORST to CORST
21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced (adrenodoxin) => corticosterone + H2O + 2 oxidized (adrenodoxin)
11-deoxycorticosterone + NADPH + H+ + O2 => corticosterone + H2O + NADP+

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:205621] Xenopus tropicalis

stId R-XTR-194017

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

(precedingEvent)

[Reaction:R-XTR-193995] CYP11B2 18-hydroxylates CORST to 18HCORST

(inferredTo)

[Reaction:R-HSA-194017] CYP11B2 oxidises 11DCORST to CORST

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