Reactome Pathway Database

Schema > Reaction > Entries

5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol Show undefined attributes

catalystActivity

[CatalystActivity:10615110] alcohol dehydrogenase (NADP+) activity of Aldo-keto reductase family [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10603480] Weiser, Joel, 2025年08月27日

dbId 10615428

displayName 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol

eventOf

[Pathway:R-XTR-193775] Synthesis of bile acids and bile salts via 24-hydroxycholesterol - Xenopus tropicalis

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-193758] 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol
5beta-cholestan-7alpha,24(S)-diol-3-one+ NADPH + H+ => 5beta-cholestan-3alpha,7alpha,24(S)-triol + NADP+

output

precedingEvent

[Reaction:R-XTR-193746] 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one - Xenopus tropicalis

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:205621] Xenopus tropicalis

stId R-XTR-193758

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-XTR-193775] Synthesis of bile acids and bile salts via 24-hydroxycholesterol

(inferredTo)

[Reaction:R-HSA-193758] 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol

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