Reactome Pathway Database

Schema > Reaction > Entries

Sequestration of BAD protein by 14-3-3 Show undefined attributes

category binding

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10603480] Weiser, Joel, 2025年08月27日

dbId 10610698

displayName Sequestration of BAD protein by 14-3-3

eventOf

[Pathway:R-XTR-111447] Activation of BAD and translocation to mitochondria - Xenopus tropicalis

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-XTR-139906] Activation of BAD by calcineurin - Xenopus tropicalis

inferredFrom

[Reaction:R-HSA-139899] Sequestration of BAD protein by 14-3-3 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Sequestration of BAD protein by 14-3-3

output

[Complex:R-XTR-139904] 14-3-3 proteins:p-S99-BAD complex [cytosol]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:205621] Xenopus tropicalis

stId R-XTR-139899

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-XTR-111447] Activation of BAD and translocation to mitochondria

(precedingEvent)

[Reaction:R-XTR-139906] Activation of BAD by calcineurin

(inferredTo)

[Reaction:R-HSA-139899] Sequestration of BAD protein by 14-3-3

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