Reactome Pathway Database

Schema > Pathway > Entries

IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation Show undefined attributes

compartment

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10539211

displayName IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation

eventOf

[Pathway:R-SSC-975138] TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

hasDiagram false

hasEHLD false

hasEvent

inferredFrom

[Pathway:R-HSA-975163] IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation - Homo sapiens

isInDisease false

isInferred true

maxDepth 2

name

IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:49633] Sus scrofa

stId R-SSC-975163

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-975138] TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation

(inferredTo)

[Pathway:R-HSA-975163] IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation

© 2025 Reactome

Cite Us!