Reactome Pathway Database

Schema > Reaction > Entries

TLE tetramers bind TCF/LEF at WNT promoters Show undefined attributes

category binding

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10521880

displayName TLE tetramers bind TCF/LEF at WNT promoters

eventOf

[Pathway:R-SSC-4641265] Repression of WNT target genes - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-8944349] TLE tetramers bind TCF/LEF at WNT promoters - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

TLE tetramers bind TCF/LEF at WNT promoters

output

[Complex:R-SSC-8944351] 'canonical' WNT target gene:TCF/LEF:TLE tetramer [nucleoplasm]

precedingEvent

[Reaction:R-SSC-4641229] TLE oligomerizes - Sus scrofa

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-8944349

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-4641265] Repression of WNT target genes

(inferredTo)

[Reaction:R-HSA-8944349] TLE tetramers bind TCF/LEF at WNT promoters

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