Reactome Pathway Database

Schema > Reaction > Entries

RET tyrosine phosphorylation Show undefined attributes

catalystActivity

[CatalystActivity:10516359] transmembrane receptor protein tyrosine kinase activity of 2x RET:GFRA:GDNF complexes [plasma membrane]

category transition

compartment

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10516361

displayName RET tyrosine phosphorylation

eventOf

[Pathway:R-SSC-8853659] RET signaling - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-8853792] RET tyrosine phosphorylation - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

RET tyrosine phosphorylation

output

precedingEvent

[Reaction:R-SSC-8853762] RET dimerizes - Sus scrofa

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-8853792

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-8853659] RET signaling

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-8853792] RET tyrosine phosphorylation

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