Reactome Pathway Database

Schema > Reaction > Entries

Benzene is hydroxylated to phenol Show undefined attributes

catalystActivity

[CatalystActivity:10431001] monooxygenase activity of Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane]

category transition

compartment

[Compartment:17960] smooth endoplasmic reticulum

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10431016

displayName Benzene is hydroxylated to phenol

eventOf

[Pathway:R-SSC-211999] CYP2E1 reactions - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:11828] benzene metabolic process

inferredFrom

[Reaction:R-HSA-76416] Benzene is hydroxylated to phenol - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Benzene is hydroxylated to phenol
Benzene + O₂ + NADPH + H⁺ -> Phenol + H₂O + NADP⁺

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-76416

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-211999] CYP2E1 reactions

(inferredTo)

[Reaction:R-HSA-76416] Benzene is hydroxylated to phenol

© 2025 Reactome

Cite Us!